| Hoole Project Solutions Limited | Professional & scientific | 2019 |
| HOP Forward Ltd | Manufacturing | 2018 |
| Hopkins Drive Limited | Hospitality | 2023 |
| Hotel Catering (New Brighton) Ltd | Hospitality | 2024 |
| House of Care Ltd | Health & social care | 2022 |
| House of Satin Sleepwear Ltd | Professional & scientific | 2020 |
| Howbeck Property Management Limited | Households | 1967 |
| Hoxter Ltd | Information & communication | 2025 |
| HR Onsite Limited | Professional & scientific | 2020 |
| HSE Projects Ltd | Professional & scientific | 2023 |
| Hsrw Consulting Limited | Professional & scientific | 2023 |
| Hume Limited | Hospitality | 2023 |
| Hutchinson Therapy Ltd | Health & social care | 2025 |
| HVQ Limited | Hospitality | 2025 |
| Hydrix Ltd | Information & communication | 2025 |
| I & M Roofing & Building Contractors Ltd | Construction | 2025 |
| IAN Carney Limited | Arts & recreation | 2014 |
| Icare Solutions Wirral Ltd | Health & social care | 2019 |
| Icolux Sport Ltd | Wholesale & retail | 2024 |
| IJP Building Supplies Ltd | Manufacturing | 2025 |
| Illuma Limited | Manufacturing | 2017 |
| Illuxium Ltd | Information & communication | 2024 |
| Imagen Archive Systems Limited | Information & communication | 2001 |
| Improve Mind Ltd | Health & social care | 2022 |
| Impulse Electrical North West Limited | Construction | 2021 |
| IN Demand Decades Ltd | Information & communication | 2024 |
| IN Demand Events Limited | Extraterritorial | 2024 |
| IN Demand Global Limited | Arts & recreation | 2021 |
| IN Demand Music Limited | Information & communication | 2015 |
| IN Demand Productions Ltd | Information & communication | 2015 |
| IN Demand Radio Limited | Information & communication | 2018 |
| IN Demand Technologies Ltd | Information & communication | 2024 |
| IN Demand Tickets Limited | Administrative & support | 2020 |
| IN Demand Training Limited | Education | 2021 |
| IN Spire Coffee Bar CIC | Hospitality | 2016 |
| Inclusive Designs Ltd | Professional & scientific | 2014 |
| Indentilam Technology Ltd | Wholesale & retail | 2024 |
| Infodial Limited | Professional & scientific | 2000 |
| Inglecray Insulation Co. Limited | Construction | 1983 |
| Inglenook Financial Services Limited | Financial services | 2006 |
| Inglenook Properties Ltd | Real estate | 2020 |
| Inkbyte Ltd | Information & communication | 2023 |
| Inner Room Building Control Limited | Construction | 2025 |
| Inntent PUB Co Limited | Hospitality | 2013 |
| Inpark Limited | Hospitality | 2024 |
| Inprint (Wirral) Ltd | Administrative & support | 2009 |
| Inside Story Marketing Ltd | Professional & scientific | 2024 |
| Insta Company North West Ltd | Wholesale & retail | 2020 |
| Institution of Electronics(The) | Professional & scientific | 1935 |
| Integrated Power International Limited | Professional & scientific | 2019 |
| Integre Building Services Limited | Manufacturing | 2011 |
| Integritas Care Ltd | Health & social care | 2024 |
| International Corporate Consultancy Services Limited | Professional & scientific | 1997 |
| International Learning Alliance Limited | Education | 2016 |
| Intubuild Ltd | Construction | 2018 |
| Invara Systems Ltd | Information & communication | 2026 |
| Invest ML Ltd. | Real estate | 2017 |
| Invision Northwest Ltd | Manufacturing | 2015 |
| ISTORE4LESS Ltd | Wholesale & retail | 2013 |
| IT Classic Cars Limited | Wholesale & retail | 2021 |
| IT Syntrix Ltd | Information & communication | 2025 |
| It'Sa Frame Ltd | Manufacturing | 2024 |
| Ivanty Dresses Ltd | Wholesale & retail | 2023 |
| IVY19 Limited | Real estate | 2021 |
| J and J Local Store Ltd | Wholesale & retail | 2025 |
| J Architectural Services Limited | Professional & scientific | 2019 |
| J J Mech Limited | Professional & scientific | 2013 |
| J Knox Ltd | Manufacturing | 2026 |
| J Leighton Ltd | Wholesale & retail | 2012 |
| J Lewis Property Assets Ltd | Real estate | 2024 |
| J Lewis Property Ltd | Households | 2023 |
| J P Fire and Safety Ltd | Manufacturing | 2024 |
| J P Personal Training Ltd | Other services | 2024 |
| J&J Joinery and Building Ltd | Construction | 2022 |
| J&K Travel Ltd | Other services | 2017 |
| J&M Cleaners Wirral Ltd | Administrative & support | 2025 |
| J&M Laundry Services Ltd | Administrative & support | 2025 |
| J&M Property Management Group Limited | Administrative & support | 2025 |
| J. Cubbin & Sons Limited | Wholesale & retail | 1947 |
| J. Houghton Catering Limited | Hospitality | 2017 |
| J.A.H Property Services Limited | Real estate | 2026 |
| J.D.M Rail Ltd | Professional & scientific | 2012 |
| Jacks Engineering Ltd | Manufacturing | 2021 |
| Jackson's of Seacombe Limited | Wholesale & retail | 2010 |
| Jadoonz Logistics Ltd | Transport & logistics | 2026 |
| JAF34 Property Ltd | Real estate | 2026 |
| Jalali (Bangladesh) Ltd | Hospitality | 2015 |
| James Rutland Marine Ltd | Transport & logistics | 2018 |
| JAN & Sobi Best Solutions Ltd | Construction | 2018 |
| JAN Plumbing Ltd | Construction | 2025 |
| Jan's Little Learners Ltd | Education | 2024 |
| Jarocki & Co Ltd | Professional & scientific | 2021 |
| Jascon Ltd | Professional & scientific | 2009 |
| Jason Management Limited | Real estate | 2000 |
| Jayne Kennedy Marketing Ltd | Professional & scientific | 2026 |
| Jayso Construction Products Ltd | Wholesale & retail | 2024 |
| JB Properties (Wirral) Ltd | Real estate | 2016 |
| JC Ecology Limited | Professional & scientific | 2018 |
| JC Waste Solutions Ltd | Water & waste | 2025 |
| JCK Investment Solutions Limited | Financial services | 2024 |