| Dynamic Food Ltd | Hospitality | 2016 |
| Dynamic Hearing Limited | Wholesale & retail | 2022 |
| Dyson & SON Electrical Ltd | Construction | 2016 |
| DZ Bespoke Installations Limited | Construction | 2015 |
| DZC Consulting Ltd | Professional & scientific | 2016 |
| E 2 M (UK) Limited | Construction | 2005 |
| E Green Animal Physiotherapy Limited | Professional & scientific | 2014 |
| E M D Parkinson Limited | Other services | 1923 |
| E OCU Transport Limited | Transport & logistics | 2018 |
| E&D Properties (Lettings) Limited | Real estate | 2024 |
| E&D Properties Limited | Real estate | 2012 |
| E&N Jepson Limited | Administrative & support | 2013 |
| E&S Installers Ltd | Construction | 2023 |
| E-Com Properties Limited | Real estate | 2016 |
| E-Stahl Limited | Professional & scientific | 2003 |
| E.H. Services (Wakefield) Ltd | Construction | 2025 |
| E.Simms & Co. Limited | Wholesale & retail | 1948 |
| E17 Engineering Limited | Professional & scientific | 2017 |
| E2 Property Investment Corporation Limited | Extraterritorial | 2020 |
| E2 Specialist Consultants Limited | Other services | 2008 |
| E2E Software Solutions Ltd | Information & communication | 2020 |
| E9 Contracts Limited | Construction | 2020 |
| Eagle Car Centre Limited | Wholesale & retail | 2010 |
| Eagle Corp Ltd | Construction | 2024 |
| Eagle EYE Security 24/7 Ltd | Administrative & support | 2020 |
| Eaglecad Limited | Construction | 2009 |
| Earguru Limited | Health & social care | 2018 |
| Earles Family Solutions Limited | Administrative & support | 2022 |
| Early Days Baby Scan Ltd | Health & social care | 2016 |
| Earth Sign Enterprises Ltd | Education | 2016 |
| Earth Tech Construction Management Limited | Construction | 2024 |
| Earth Tech Consulting Limited | Professional & scientific | 2004 |
| Earth Tech Developments Limited | Construction | 2024 |
| Earth Tech Easington Limited | Real estate | 2024 |
| Earth Tech Estates Limited | Real estate | 2024 |
| Earth Tech Holdings Limited | Financial services | 2022 |
| Earth Tech Wintersett Limited | Real estate | 2019 |
| Earthaware Ltd | Wholesale & retail | 2018 |
| Earthed Electrical Supplies Ltd | Wholesale & retail | 2022 |
| Earthgb Limited | Construction | 2000 |
| Earthmover Tyres (Wakefield) Limited | Wholesale & retail | 2013 |
| East Coast Property Holdings Ltd | Real estate | 2023 |
| East Leeds Block 1 Residents Management Company Limited | Households | 2024 |
| East Leeds Blocks 2 & 3 Residents Management Company Limited | Households | 2024 |
| East Leeds Residents Management Company Limited | Households | 2024 |
| Easthorpe Panel Limited | Professional & scientific | 1990 |
| Eastmoor Amateur Sports Club Limited | Arts & recreation | 1974 |
| Eastmoor Community Project Limited | Health & social care | 2002 |
| Eastmoor Healthcare Ltd | Wholesale & retail | 2026 |
| Easy Bathrooms Limited | Wholesale & retail | 2019 |
| Easy Catering Services Ltd | Information & communication | 2018 |
| Easy Hygiene Limited | Extraterritorial | 2008 |
| EASY2DISPLAY Limited | Administrative & support | 2006 |
| Easymedal Limited | Wholesale & retail | 1992 |
| Easymind Limited | Professional & scientific | 2012 |
| Easypmo Ltd | Professional & scientific | 2024 |
| Easyreaduk Limited | Professional & scientific | 2017 |
| EAT 88 Limited | Hospitality | 2014 |
| EAT the Frog Consultancy Ltd | Construction | 2018 |
| Eazee Payment Solutions Limited | Financial services | 2024 |
| EBI Barza Limited | Real estate | 2022 |
| EBR Property Services Limited | Construction | 2020 |
| ECB 2022 Ltd | Real estate | 2022 |
| ECB Coaching Ltd | Other services | 2022 |
| Echofy Ltd | Professional & scientific | 2025 |
| Ecigs Direct Ltd | Wholesale & retail | 2022 |
| Ecklands Development Ltd | Construction | 2025 |
| Eclipse ALL Sports Ltd | Wholesale & retail | 2013 |
| Eclipse Cricket Ltd | Extraterritorial | 2020 |
| Eclipse Rentals Limited | Administrative & support | 2016 |
| Ecnite Innovations Ltd | Professional & scientific | 2018 |
| Eco Food Group Limited | Hospitality | 2024 |
| Eco Garden Ltd | Wholesale & retail | 2020 |
| Eco-Smart Construction Limited | Construction | 2006 |
| Ecocell Ltd | Construction | 2014 |
| Ecoclean Leeds Limited | Administrative & support | 2022 |
| Econ Electrical Ltd | Construction | 2021 |
| Econ Property Ltd | Real estate | 2023 |
| Ecospec Ltd | Construction | 2023 |
| ECT Holdings Limited | Financial services | 2019 |
| Edban Ltd | Real estate | 2026 |
| Edbwn Limited | Information & communication | 2023 |
| Edco Holdings Ltd | Financial services | 2026 |
| Edco Search Ltd | Administrative & support | 2026 |
| Eddison & Wanless Limited | Manufacturing | 1989 |
| Eden Fine China Ltd | Manufacturing | 2015 |
| Eden Mill Property Limited | Real estate | 2020 |
| Eden Soleil Ltd | Wholesale & retail | 2025 |
| Eden Vale Food Ingredients Limited | Professional & scientific | 1942 |
| Eden-Poppy Ceramics Ltd | Manufacturing | 2023 |
| Edenthorpe Projects (Pontefract) Limited | Real estate | 2018 |
| Edge DEV Studio Ltd | Information & communication | 2024 |
| Edgeineering Innovations Ltd | Manufacturing | 2020 |
| Edghill Consultancy Ltd | Professional & scientific | 2026 |
| Edifice (Yorkshire) Ltd | Construction | 2019 |
| Edmlo Group Limited | Real estate | 2017 |
| Edres Mahmud Ltd | Administrative & support | 2016 |
| Edtp Services Ltd | Arts & recreation | 2024 |
| Educating Earth Ltd | Education | 2018 |
| Education 707 LP | | 2011 |