| Priory Hill Property & Investment Co. Limited | Real estate | 1957 |
| Proaction Consulting Limited | Professional & scientific | 2015 |
| Produco Ltd | Financial services | 2019 |
| Progredi Holdings Limited | Financial services | 2017 |
| Proof of Work Studio Ltd | Professional & scientific | 2024 |
| Protea Derivatives Limited | Financial services | 2010 |
| Purtek Limited | Administrative & support | 2006 |
| Pyrogem Limited | Professional & scientific | 2021 |
| Quantum UK UW Ltd | Financial services | 2025 |
| Queensland Place RTM Company Limited | Households | 2023 |
| Quest for Nature Ltd | Information & communication | 2026 |
| Quillay Ltd | Real estate | 2026 |
| Quotemycaravan Limited | Financial services | 2008 |
| R&R Optical Ltd | Manufacturing | 2019 |
| RAY Lodge RTM Company Limited | Households | 2026 |
| RB SE26 RTM Company Limited | Households | 2026 |
| RBK Marketing Ltd | Professional & scientific | 2018 |
| RDG Advisory Ltd | Professional & scientific | 2026 |
| Recruiter on Demand Ltd | Administrative & support | 2020 |
| Red Holdings Group Limited | Financial services | 2024 |
| Rendercare Limited | Construction | 2014 |
| Research Vision Limited | Financial services | 1993 |
| River Lodge Management Limited | Households | 1998 |
| River Trading Ltd | Professional & scientific | 2026 |
| Riverview Court (CF5) RTM Company Limited | Households | 2024 |
| RM Retail Solutions Ltd | Wholesale & retail | 2025 |
| Robin Beckham Images Limited | Other services | 2006 |
| Rock Robin ROW Residents Association Limited | Professional & scientific | 2006 |
| Rokie Ltd | Hospitality | 2024 |
| Rootsbuds Limited | Construction | 2018 |
| Rosa REU Limited | Wholesale & retail | 2024 |
| Rosebay RTM Company Limited | Households | 2025 |
| Ross Management Consultancy Limited | Professional & scientific | 2010 |
| Roxanne Nazrudeen Limited | Professional & scientific | 2010 |
| RSA Taxi Limited | Transport & logistics | 2009 |
| Rubble Development Ltd | Real estate | 2025 |
| S & D Commercials Ltd. | Wholesale & retail | 2012 |
| S. Hayes Engineering Design Limited | Professional & scientific | 2007 |
| Safer-Idd CIC | Health & social care | 2024 |
| Sapore Coffee Ltd | Wholesale & retail | 2023 |
| SB 10 Construction Limited | Construction | 2013 |
| SB 10 Homes Limited | Construction | 2020 |
| Scream Retail Limited | Manufacturing | 1995 |
| SDR Autos Limited | Wholesale & retail | 2004 |
| Securafit Limited | Extraterritorial | 2012 |
| Sedgwick Company Management Limited | Administrative & support | 2014 |
| Sellitbetter Limited | Information & communication | 2009 |
| Sellons Avenue RTM Company Limited | Households | 2025 |
| SG Gardening Services Ltd Ltd | Administrative & support | 2022 |
| Sheppy Industries Limited | Real estate | 1887 |
| Sheppy Limited | Real estate | 1981 |
| Shift Construction Ltd | Education | 2023 |
| Siamo Sarto Ltd | Professional & scientific | 2020 |
| Sign-Tec Services Limited | Wholesale & retail | 2000 |
| Silly Ghillie Limited | Wholesale & retail | 2022 |
| Silverhill Restaurants Ltd | Hospitality | 2024 |
| SK Brothers Limited | Health & social care | 2015 |
| Skinner Site Management Ltd | Construction | 2026 |
| Skyline Central One RTM Company Limited | Households | 2023 |
| Smart Bits Telephone Accessories Limited | Wholesale & retail | 2017 |
| Smart Building Management Systems Ltd | Financial services | 2023 |
| Smart Chap Limited | Other services | 2025 |
| Smash Management Limited | Administrative & support | 2013 |
| Snövia Limited | Wholesale & retail | 2025 |
| Social Lift Marketing Ltd | Professional & scientific | 2023 |
| Solanum Engineering Limited | Professional & scientific | 2015 |
| South Eastern Equestrian Services Ltd. | Arts & recreation | 1993 |
| Southborough Scaffold Services Ltd | Construction | 1998 |
| Spice Cottage (UK) Ltd | Hospitality | 2007 |
| Spur Creative Investments Limited | Extraterritorial | 2017 |
| Spur Creative Limited | Arts & recreation | 2009 |
| ST Helens (Broadstairs) RTM Company Limited | Households | 2023 |
| ST Hilary (SS9) RTM Company Limited | Households | 2026 |
| ST Kathryns Place RTM Company Limited | Households | 2026 |
| ST Pauls (Broadstairs) RTM Company Limited | Households | 2023 |
| ST Stephens (Broadstairs) RTM Company Limited | Households | 2023 |
| St.Clair Bishop Ltd. | Information & communication | 2016 |
| Stannary Place RTM Company Limited | Households | 2024 |
| Start Then Scale Limited | Professional & scientific | 2025 |
| Station Garage Hassocks Ltd | Wholesale & retail | 2008 |
| Stephanie Greenland Consulting Ltd | Professional & scientific | 2022 |
| Stewart Brothers Concrete Limited | Manufacturing | 2017 |
| Stonebridge Talent Ltd | Professional & scientific | 2024 |
| Stonegate Court Management Limited | Households | 1985 |
| Stowe Lodge RTM Company Limited | Households | 2022 |
| Sussex Consultant Solutions Ltd. | Information & communication | 2026 |
| Sussex Seasons Ltd | Administrative & support | 2017 |
| Sussex Underwriting Management Limited | Financial services | 2016 |
| Sustainable Meat Eater Ltd | Wholesale & retail | 2022 |
| Swan Residential Limited | Real estate | 2024 |
| Sweetwater Resources Limited | Professional & scientific | 2003 |
| Swift Interiors & Facilities Ltd | Construction | 2010 |
| Tate & Tonbridge Automation Limited | Construction | 2019 |
| Tate and Tonbridge Fencing Limited | Manufacturing | 2015 |
| Tate Fencing Limited | Manufacturing | 2008 |
| Taylan Carpentry & Construction Ltd | Construction | 2018 |
| Taylorbrooks Metalworks Ltd | Manufacturing | 2014 |
| Teklima Limited | Construction | 1983 |
| THE 56 RTM Company Limited | Households | 2026 |
| THE Bowers Investment Company Limited | Administrative & support | 2017 |