| Securevalue Limited | Professional & scientific | 2019 |
| SEM Electrical Contractors Limited | Construction | 2015 |
| Sernya Ltd | Professional & scientific | 2024 |
| Seven Bays Lettings Limited | Hospitality | 2016 |
| Sgar Consultancy Limited | Administrative & support | 2015 |
| Shark Steel Services Ltd | Extraterritorial | 2006 |
| Sharp's Brewery Limited | Manufacturing | 2003 |
| She's Worth IT CIC | Education | 2013 |
| Siteworks Retail Limited | Construction | 2013 |
| Skyblueproperties (Cornwall) Ltd | Real estate | 2012 |
| Skylight Trading Limited | Real estate | 2002 |
| Slipper Rock Ltd | Professional & scientific | 2015 |
| Smarthouse Audio Visual Ltd | Construction | 2021 |
| Soch EOD Limited | Administrative & support | 2018 |
| Solera Associates Ltd | Construction | 1996 |
| Solve Web Media Ltd | Information & communication | 2015 |
| South East Architecture and Design Ltd | Professional & scientific | 2019 |
| South West Design Studio Limited | Information & communication | 2006 |
| Southernwood Services Limited | Professional & scientific | 2006 |
| Southwestern Distillery Limited | Manufacturing | 2012 |
| SP Civil Design Limited | Administrative & support | 2007 |
| Specbuild Ltd | Construction | 2014 |
| Specialist BIO Services Limited | Professional & scientific | 2024 |
| Sperry Fabric Architecture UK Ltd | Professional & scientific | 2016 |
| Spray Station Limited | Construction | 2016 |
| Spring Meadow Limited | Construction | 2003 |
| Springfield House (Wadebridge) Management Limited | Administrative & support | 2001 |
| Spyrys Limited | Wholesale & retail | 2012 |
| SSL (Surrey) Property Ltd | Real estate | 2025 |
| ST Eval Area Community Action Forum (Seacaf) CIC | Wholesale & retail | 2011 |
| ST Eval Candle Co Ltd | Manufacturing | 2002 |
| ST Eval Community Land Project CIC | Arts & recreation | 2023 |
| ST Eval Kart Circuit Limited | Extraterritorial | 2024 |
| ST Minver CLT Limited | Professional & scientific | 2006 |
| ST. Eval Stores Limited | Wholesale & retail | 2013 |
| ST. Giles House (Management) Limited | Households | 1978 |
| ST. Teath Homes Limited | Construction | 2009 |
| Stanchura Ltd | Construction | 2015 |
| Stanley (Residents) Limited | Hospitality | 1996 |
| Stansol Limited | Energy | 2013 |
| Stay Create Cornwall Ltd | Hospitality | 2025 |
| Step Engineering Limited | Professional & scientific | 2019 |
| Stitch'In Kernow CIC | Education | 2020 |
| Stockdale Accountants Limited | Professional & scientific | 2013 |
| Storer Consultants Ltd | Professional & scientific | 2018 |
| STORM80 Ltd | Wholesale & retail | 2026 |
| Strong Adolfos Limited | Hospitality | 2016 |
| Studio Number SIX Ltd | Information & communication | 2025 |
| Sugar Spice U.K. Limited | Manufacturing | 2008 |
| Sunstone Advisory Limited | Professional & scientific | 2024 |
| Supatrade Limited Liability Company | | 1992 |
| Surf's UP! Surf Co Limited | Arts & recreation | 2008 |
| Surfit Limited | Arts & recreation | 2005 |
| SW Fire Risk Assessments Ltd | Professional & scientific | 2025 |
| Swift Financial Planning Limited | Financial services | 2014 |
| Talk Feel Change Ltd | Information & communication | 2019 |
| TAP Gateway Ltd | Information & communication | 2019 |
| Tapper Wilson Creative Limited | Information & communication | 2014 |
| Tasteofcornwall Ltd | Wholesale & retail | 2021 |
| TDQ Services Ltd | Hospitality | 2026 |
| Teleproject UK Limited | Information & communication | 2009 |
| Tevi LAB Ltd | Professional & scientific | 2025 |
| THE Camel Buggy Company Limited | Transport & logistics | 2021 |
| THE Cornish Sign Company Limited | Manufacturing | 1991 |
| THE Cornwall Kitchen Company Ltd | Professional & scientific | 2019 |
| THE Cornwall Laser & Skin Clinic Ltd | Other services | 2019 |
| THE Dogs Code Ltd | Education | 2018 |
| THE Drawing Board Communications LLP | | 2005 |
| THE Future of Compliance Ltd | Information & communication | 2025 |
| THE GAP Cornwall C.I.C. | Hospitality | 2026 |
| THE Half Moon Soap Company Limited | Manufacturing | 2026 |
| THE Holmbush Inn Ltd | Hospitality | 2022 |
| THE London BUS Theatre CIC | Education | 2006 |
| THE Marine Surveying Society Limited | Professional & scientific | 2010 |
| THE Milk Shed Ltd | Hospitality | 2013 |
| THE Museum of Magic and Witchcraft Limited | Extraterritorial | 2009 |
| THE Museum of Witchcraft & Magic Limited | Arts & recreation | 1996 |
| THE Museum of Witchcraft Limited | Extraterritorial | 2009 |
| THE North Coast PUB Company Ltd | Hospitality | 2026 |
| THE Old Ship Hotel Limited | Hospitality | 2008 |
| THE Peckish Pony Ltd | Hospitality | 2023 |
| THE Present Drawer Limited | Wholesale & retail | 2019 |
| THE Prime Partnership (UK) Limited | Professional & scientific | 2009 |
| THE Road to Happiness Limited | Arts & recreation | 2012 |
| THE Seascape (Polzeath) Limited | Households | 2006 |
| THE Tuck Truck Limited | Hospitality | 2024 |
| THE Vault Arcade Ltd | Arts & recreation | 2024 |
| THE Wadebridge WE Want C.I.C. | Public administration | 2025 |
| THE Warrior Tribe Limited | Arts & recreation | 2019 |
| THE Wonky Agency Ltd | Professional & scientific | 2017 |
| THE Wonky Donkey Bar Ltd | Hospitality | 2023 |
| Thematic Solutions Limited | Financial services | 2018 |
| Thewhiteboard Ltd | Administrative & support | 2014 |
| THS Garden Care Limited | Administrative & support | 2021 |
| Thvcs Limited | Professional & scientific | 2025 |
| Tidal Estuary Property Management Ltd | Households | 2025 |
| Tides Psychology Services Limited | Health & social care | 2014 |
| TIM Walton Builders Wadebridge Ltd. | Construction | 2011 |
| Time World Services Limited | Other services | 2021 |
| Tintagel Brewing Company Ltd | Manufacturing | 2024 |