| RJS Lettings Limited | Real estate | 2017 |
| RJS247 Limited | Construction | 2015 |
| RM Horticulture Ltd | Administrative & support | 2021 |
| Robert Fowler and Associates Limited | Professional & scientific | 2004 |
| Robert Reay Landscaping Limited | Administrative & support | 2014 |
| Robin Sharphouse Limited | Professional & scientific | 2021 |
| Rossall Rentals Ltd | Hospitality | 2026 |
| Rossall Roofing Ltd | Construction | 2022 |
| Roundhills Kennels Limited | Other services | 2021 |
| Roundhills Properties Limited | Real estate | 2026 |
| RSJ Lettings Ltd | Real estate | 2021 |
| Rudy's Workshop Ltd | Manufacturing | 2026 |
| Rusland Chiropody Limited | Health & social care | 2003 |
| Rusland Valley Horticultural Society Limited | Other services | 2019 |
| S & E Whitaker Limited | Other services | 2006 |
| S & H Barclay Limited | Professional & scientific | 2018 |
| S & J Mcmullen Limited | Professional & scientific | 2018 |
| S & SA Webster Ltd | Agriculture & fishing | 2014 |
| S L Hospitality Limited | Hospitality | 2013 |
| S.G. Oils Limited | Water & waste | 2004 |
| S.L.P.Building Maintenance Limited | Construction | 2011 |
| S2F Limited | Manufacturing | 2000 |
| Sagemile Limited | Hospitality | 1987 |
| SAM Shaw Kilburn Stonework Limited | Manufacturing | 2019 |
| Samantha Morgan Limited | Other services | 2006 |
| Samosc Ltd | Professional & scientific | 2012 |
| SC Property Durham Ltd | Extraterritorial | 2023 |
| SC Smith ENG Limited | Construction | 2015 |
| Scandic House Limited | Hospitality | 2022 |
| Scenic Acoustic and Vibration Engineering Limited | Professional & scientific | 2007 |
| School Mews Ulverston Management Company Limited | Real estate | 2012 |
| Screpta Limited | Extraterritorial | 2001 |
| Seager Engineering Design Limited | Administrative & support | 2013 |
| Selfish Lingerie Limited | Wholesale & retail | 2024 |
| Sequoia Law Limited | Professional & scientific | 2024 |
| Sgrl Limited | Hospitality | 2019 |
| Shed 1 Distillery Ulverston. Limited | Manufacturing | 2016 |
| Shellys Drinks Limited | Wholesale & retail | 2017 |
| Shindig Furness C.I.C. | Administrative & support | 2024 |
| Ship Inn Go Ltd | Hospitality | 2026 |
| Shire Yard Events Ltd | Arts & recreation | 2025 |
| Sigma Bird Limited | Information & communication | 2025 |
| Simon Robinson Electrical Contractor Limited | Construction | 2013 |
| Singing Surf Limited | Professional & scientific | 2018 |
| SJ Agriculture Ltd | Agriculture & fishing | 2023 |
| SJM Consultancy (NW) Limited | Construction | 2026 |
| SK & AB Ltd | Professional & scientific | 2022 |
| Skiprat Design Ltd | Professional & scientific | 2022 |
| Skygaze Drone Services Limited | Professional & scientific | 2018 |
| SL Brighton Limited | Professional & scientific | 2017 |
| Slade Plumbing, Heating and Renewables Limited | Construction | 2014 |
| Smart Methane Limited | Wholesale & retail | 2023 |
| Smart-Home Cctv & Security Limited | Information & communication | 2022 |
| Soji Property Investment Limited | Real estate | 2021 |
| Soldat Schmidt Ltd | Arts & recreation | 2020 |
| Soulby House Management Company Limited | Households | 2005 |
| Sound Intervention Limited | Arts & recreation | 2008 |
| Soutergate Environmental Limited | Professional & scientific | 2002 |
| South Cumbria Rivers Trust Limited | Administrative & support | 2006 |
| South Lakes Canine Hydrotherapy Limited | Other services | 2015 |
| South Lakes Cleaning Services Limited | Administrative & support | 2025 |
| South Lakes Getaways Limited | Hospitality | 2022 |
| South Lakes Lawncare Ltd | Administrative & support | 2019 |
| South Lakes Sparkle and Shine Ltd | Administrative & support | 2025 |
| South Lakes Tree Services Limited | Agriculture & fishing | 2021 |
| South Lakes Tree Surgeons & Landscapes Limited | Agriculture & fishing | 2005 |
| South Lakes Tuition Ltd | Education | 2025 |
| Spanner Limited | Information & communication | 1997 |
| Spanner Monkey Ltd | Manufacturing | 2023 |
| Spear Freehold Ltd | Financial services | 2021 |
| Spear Holdings Ltd | Real estate | 2021 |
| Splc Ltd | Professional & scientific | 2024 |
| Spled Limited | Administrative & support | 2012 |
| Sportive Lakes Ltd | Arts & recreation | 2013 |
| Spray Plaster Systems Limited | Manufacturing | 2020 |
| Spruce Interiors Ltd | Professional & scientific | 2022 |
| SPW 21 Ltd | Administrative & support | 2009 |
| ST Andrews Garden Bar Ltd | Extraterritorial | 2018 |
| ST Helens Eats Ltd | Hospitality | 2020 |
| ST Marys Mount Guest House Limited | Hospitality | 2024 |
| Stables Engineering Ltd | Professional & scientific | 2022 |
| Stanyan Lodge Management Company Limited | Households | 1986 |
| STAR5TRAVEL Limited | Administrative & support | 2025 |
| Stephen Hargreaves Properties Ltd | Financial services | 2005 |
| Stephen Marshall Construction Limited | Manufacturing | 2021 |
| Steven Martin & Associates Limited | Professional & scientific | 2006 |
| Steven Smith Joinery (Ulverston) Limited | Construction | 2005 |
| Still Life Art House Limited | Wholesale & retail | 2022 |
| Stillingpoint Limited | Professional & scientific | 2025 |
| Sting in the Tail Limited | Wholesale & retail | 2024 |
| Stockbridge Court Limited | Households | 2004 |
| Strategic Oriental Limited | Financial services | 2020 |
| Sub-Tech Systems Management Limited | Professional & scientific | 1999 |
| Summer Hill House Management Company Limited | Households | 2011 |
| Sunderland City Eats Limited | Hospitality | 2021 |
| Super Specs Ltd | Wholesale & retail | 2021 |
| Superior Contractor Accommodation Ltd | Real estate | 2021 |
| Sure 2 Save Limited | Financial services | 2003 |
| Suryanamaskar Limited | Other services | 2022 |
| Sustain Collective @ Evermore Limited | Wholesale & retail | 2011 |