| Development in Partnership Ltd | Construction | 2026 |
| Devpuja Infotech Limited | Information & communication | 2010 |
| DFW Contracting Limited | Professional & scientific | 2023 |
| DGH GAS Ltd | Construction | 2015 |
| DGM Construction Services Limited | Construction | 2020 |
| Dgod Consulting Ltd | Professional & scientific | 2026 |
| Dhillon GB Investments Ltd | Real estate | 2024 |
| Dhillon Housing Group Ltd | Construction | 2020 |
| Dhillon UK Investments Ltd | Real estate | 2023 |
| Dhruv Heating and Plumbing Ltd | Construction | 2023 |
| Dhyan Group Limited | Wholesale & retail | 2017 |
| DI Giulio Limited | Construction | 2009 |
| Dialogue Press Ltd | Information & communication | 2010 |
| Diffal Ltd | Construction | 2023 |
| Digidisruptor Limited | Information & communication | 2022 |
| Digital Accountancy Media Limited | Administrative & support | 2018 |
| Digital Network Security Ltd | Information & communication | 2025 |
| Digital Solution Technology Ltd | Information & communication | 2020 |
| Digory Price Recording Limited | Information & communication | 2025 |
| Dimedis Associated Laboratories UK Ltd | Wholesale & retail | 2021 |
| Dinance Consulting Limited | Professional & scientific | 2015 |
| Dinghar Ltd | Real estate | 2023 |
| Dioom Limited | Wholesale & retail | 2024 |
| Direct Consulting Ltd | Real estate | 2018 |
| Direct Support Limited | Information & communication | 2001 |
| Discoveree Software Ltd | Information & communication | 2026 |
| Display Block Limited | Administrative & support | 2014 |
| District Construction Ltd | Administrative & support | 2019 |
| Ditsy & Stitch Limited | Extraterritorial | 2023 |
| Diva Food and Wine Limited | Wholesale & retail | 2016 |
| Divine Films Limited | Information & communication | 2016 |
| DK Retail Limited | Extraterritorial | 2012 |
| DK Stained & Leaded Glass Ltd | Manufacturing | 2023 |
| Dkyk Limited | Wholesale & retail | 2018 |
| DL Contractor Services Limited | Construction | 2024 |
| DLB Accounts at Your Hands Ltd | Extraterritorial | 2020 |
| DLC Consulting Limited | Professional & scientific | 2023 |
| DLN Services Ltd | Administrative & support | 2019 |
| DM Exports Limited | Administrative & support | 2016 |
| DNA Finishes Limited | Construction | 2016 |
| DND Facades Ltd | Construction | 2019 |
| DNS Trade Limited | Wholesale & retail | 2024 |
| Do-Ri-Me Ltd. | Information & communication | 2014 |
| Dog Tooth Productions Ltd | Information & communication | 2025 |
| Dolan & Associates Limited | Professional & scientific | 1994 |
| Dollys Donuts Ltd | Hospitality | 2024 |
| DOM Solutions Ltd | Information & communication | 2012 |
| DON Weekend Limited | Administrative & support | 2016 |
| Don'T BE Doin' That Limited | Information & communication | 2002 |
| Donald Alexander Ltd | Manufacturing | 2019 |
| Doodle Development Limited | Administrative & support | 2021 |
| Door Thirty Five Limited | Professional & scientific | 2026 |
| Doors 4 Garages Ltd | Construction | 2018 |
| Dorchester Mews Management Company Ltd | Households | 2026 |
| Dorroy Limited | Real estate | 2015 |
| Doubellix Advisory Ltd | Information & communication | 2026 |
| Double Deli Ltd | Wholesale & retail | 2021 |
| Dovecote Enterprises Ltd | Extraterritorial | 2022 |
| Doveguard Construction Services Limited | Households | 2009 |
| Down Syndrome Swimming Great Britain | Administrative & support | 2016 |
| Downside Family Holdings Limited | Professional & scientific | 2025 |
| Dpconnections Ltd | Construction | 2024 |
| DPM Twenty Four Seven Care Services Ltd | Health & social care | 2022 |
| DR. Whisky Limited | Manufacturing | 2020 |
| DRG Medical Limited | Health & social care | 2014 |
| DRH Management and Consultancy Services Limited | Professional & scientific | 2008 |
| Drinks Distro Group Ltd | Wholesale & retail | 2025 |
| DRM Building Contractors Limited | Construction | 2021 |
| Droclo Limited | Information & communication | 2025 |
| Drone Approach Ltd | Professional & scientific | 2020 |
| Drone Inspection Company Limited | Professional & scientific | 2017 |
| Droproot Product LAB Ltd | Information & communication | 2025 |
| DRS Electrical Ltd | Construction | 2026 |
| Drysure Roofing London Ltd | Construction | 2025 |
| DS22 Property Investment Ltd | Real estate | 2017 |
| DS365 Ecommerce Ltd | Wholesale & retail | 2021 |
| Dsignature Interiors Ltd | Manufacturing | 2022 |
| DSS (Soho) Limited | Hospitality | 2022 |
| Dtdc Courier & Cargo (UK) Limited | Transport & logistics | 2006 |
| DTK Construction Limited | Construction | 2021 |
| DTN Consulting Ltd | Information & communication | 2011 |
| DUE Passi Ltd | Hospitality | 2011 |
| Duiker Limited | Hospitality | 2014 |
| Duka Limited | Real estate | 2002 |
| Dunfionn Ventures Limited | Professional & scientific | 2018 |
| DUO Design Ltd | Professional & scientific | 2021 |
| Durable GTM Ltd | Professional & scientific | 2026 |
| Durban Cowboy Limited | Information & communication | 2018 |
| Durvesh Ltd | Manufacturing | 2021 |
| DVI Decor Ltd | Construction | 2014 |
| DW Holdco Ltd | Financial services | 2025 |
| Dynamic Perspectives Ltd | Professional & scientific | 2025 |
| DZ Build Limited | Construction | 2017 |
| E Dexter Systems Ltd | Professional & scientific | 2026 |
| E Smart Electrical Solutions Ltd | Construction | 2026 |
| E W S Consulting Limited | Professional & scientific | 2015 |
| E-Z-Tek Couplings Limited | Professional & scientific | 2008 |
| EAS22 Ltd | Hospitality | 2019 |
| Easn Limited | Wholesale & retail | 2023 |
| East River Development Ltd | Real estate | 2017 |