| Studio Mercer Limited | Professional & scientific | 2025 |
| Studio Monthan Ltd | Professional & scientific | 2022 |
| Studio N Dance Limited | Arts & recreation | 2016 |
| Studio Thirteen Salon Limited | Other services | 2022 |
| Studio Welkin Ltd | Professional & scientific | 2024 |
| Studiomade Limited | Professional & scientific | 2016 |
| Stumpfle Medical Limited | Health & social care | 2021 |
| Stun Investments Limited | Administrative & support | 2015 |
| Sturdy Ltd | Professional & scientific | 2018 |
| Sturgeon's (Civil Engineering) Limited | Construction | 2012 |
| Sturgeons Assets LLP | | 2018 |
| Sturgeons Holdings Limited | Financial services | 2018 |
| STW Fabrications Limited | Construction | 2005 |
| SUB Connect Ltd | Other services | 2024 |
| Substantial Films Ltd | Information & communication | 2010 |
| Substatic Ltd | Information & communication | 2025 |
| Success Coach RF Limited | Professional & scientific | 2022 |
| Success Media Limited | Professional & scientific | 2007 |
| Such Agency Ltd | Professional & scientific | 2019 |
| Suchitra Enterprises Limited | Hospitality | 2001 |
| Sugak Consulting Ltd | Professional & scientific | 2025 |
| Sugar & Splice Limited | Information & communication | 2016 |
| Sugar Loaf Farm Ltd | Hospitality | 2025 |
| Sugar Loaf Yard Ltd | Administrative & support | 2025 |
| Sugar Loaf Yardspace Ltd | Administrative & support | 2025 |
| Sugar Marketing Limited | Professional & scientific | 2008 |
| Sugarbird Solutions Limited | Extraterritorial | 2013 |
| Sugarbush Promotions Limited | Information & communication | 2015 |
| SUM Quod SUM Limited | Professional & scientific | 2010 |
| Summation Limited | Professional & scientific | 2019 |
| Summerseries Limited | Arts & recreation | 2025 |
| Sun Central Ltd | Other services | 2022 |
| Sun Jellies Limited | Manufacturing | 2013 |
| Sun SKP Limited | Wholesale & retail | 2015 |
| Sunbeam Hats Ltd | Wholesale & retail | 2020 |
| Sunday Productions Ltd | Arts & recreation | 2013 |
| Sunflour Power Limited | Hospitality | 2021 |
| Sunley (Chilton Manor) Residents Limited | Households | 1987 |
| Sunnset Homes Ltd | Real estate | 2022 |
| Sunnyside Hall, Rusthall | Administrative & support | 2003 |
| Sunnyside Road Management Company Limited | Real estate | 2008 |
| Sunpint Ltd | Professional & scientific | 2015 |
| Sunrise Grove Montessori Ltd | Health & social care | 2025 |
| Sunseeker Marine Management Ltd | Transport & logistics | 2014 |
| Sunshine & Tiger Limited | Real estate | 2016 |
| Sunshine Advisory Ltd | Information & communication | 2026 |
| Superior Interiors & Exteriors Ltd | Construction | 2020 |
| Superlet Management Limited | Construction | 2023 |
| Supermax Estate Limited | Real estate | 2025 |
| Supreme Networks Limited | Wholesale & retail | 2024 |
| Surefoot Studio Ltd | Wholesale & retail | 2019 |
| Surplies Limited | Extraterritorial | 2008 |
| Surprisingly Ltd | Information & communication | 2021 |
| Surrey Golf LAB Limited | Arts & recreation | 2019 |
| Surrey Scaffold Limited | Construction | 2009 |
| Sushi Works Ltd | Hospitality | 2025 |
| Sussex Shaw Limited | Households | 1967 |
| Sussex Yacht Services (UK) LLP | | 2015 |
| Sustainable Packaging Limited | Administrative & support | 2017 |
| SV Event Consulting Limited | Other services | 2015 |
| Swallows Oast Limited | Hospitality | 2001 |
| Swaminarayana Limited | Wholesale & retail | 2025 |
| Swan Contracting Services Ltd | Construction | 2006 |
| Swan Labels Ltd | Wholesale & retail | 2023 |
| Swan Web Ltd | Information & communication | 2026 |
| SWANS5 Limited | Professional & scientific | 2023 |
| Swarbourne Consultants Limited | Financial services | 2025 |
| Swarm Creative & Film Ltd | Information & communication | 2018 |
| Swastik Spice Fusion Ltd | Hospitality | 2025 |
| Swatlands Limited | Administrative & support | 2014 |
| SWC Partnership Ltd | Professional & scientific | 2014 |
| Sweeter Limited | Administrative & support | 2010 |
| Swift Ideas Ltd | Information & communication | 2012 |
| Swift Tech Ltd | Information & communication | 2023 |
| Swiftdean Ltd | Professional & scientific | 2019 |
| Swiftech Limited | Information & communication | 2013 |
| Swiftech Tonbridge Ltd | Wholesale & retail | 2017 |
| Swim Collective Limited | Arts & recreation | 2011 |
| Swimon Ltd | Manufacturing | 2026 |
| Switch-It Limited | Extraterritorial | 2020 |
| SY Pulse Group Ltd | Arts & recreation | 2025 |
| Sycamore Cottages Residents Limited | Real estate | 1982 |
| Sylco Store Ltd | Wholesale & retail | 2025 |
| Sylvacore Consultancy Limited | Administrative & support | 2026 |
| Sylvagen Limited | Agriculture & fishing | 2017 |
| SYM Music Company Limited | Arts & recreation | 1986 |
| Symmetry Events Ltd | Administrative & support | 2004 |
| Synchpoint Limited | Information & communication | 2009 |
| Synergee Limited | Professional & scientific | 2003 |
| Synergise Tech Limited | Information & communication | 2025 |
| Synopcare Ltd | Information & communication | 2025 |
| Synoptra Engineering Ltd | Professional & scientific | 2026 |
| Syntaxio Ltd | Information & communication | 2022 |
| Synthex Limited | Information & communication | 2023 |
| Systemgrand Limited | Households | 1995 |
| Systems Thinking UK Limited | Extraterritorial | 2005 |
| Systemsmanaged Ltd | Information & communication | 2006 |
| T & F Catering Limited | Extraterritorial | 2018 |
| T & I Executive Travel Service Ltd | Transport & logistics | 2018 |
| T & N Browne Limited | Health & social care | 2012 |