| Skinny BOY Boxing Club Limited | Arts & recreation | 2021 |
| Skint Media Limited | Administrative & support | 2016 |
| Skip N TIP Recycling Ltd | Water & waste | 2026 |
| Skipaway Limited | Water & waste | 2022 |
| Skycrane Technologies Limited | Information & communication | 2014 |
| Skylar Design Limited | Other services | 2012 |
| Skylex Label Company Ltd | Wholesale & retail | 2019 |
| Skyline International Limited | Wholesale & retail | 2025 |
| Skyoworld Ltd | Administrative & support | 2017 |
| Slats & Wills Films PTY Ltd | Administrative & support | 2004 |
| Sleeping and Breathing Limited | Health & social care | 2014 |
| Slicreal (UK) Limited | Real estate | 2021 |
| Slicsoft (UK) Limited | Information & communication | 2013 |
| SLR Services Limited | Administrative & support | 2023 |
| SM Terra Investment Limited | Real estate | 2023 |
| SM Terra Limited | Real estate | 2026 |
| SM Terra Property Management LLP | | 2023 |
| Smak Projects Ltd | Real estate | 2025 |
| Small Boutique Hotels Limited | Extraterritorial | 2018 |
| Small Cars 4U Limited | Wholesale & retail | 2006 |
| Smart Chaps Male Grooming Limited | Other services | 2019 |
| Smart Creativity Limited | Professional & scientific | 2024 |
| Smart Epos Solutions Limited | Wholesale & retail | 2013 |
| Smart Marketing Ltd | Professional & scientific | 2020 |
| Smart Move Home Search Limited | Real estate | 2017 |
| Smartchip Solutions Limited | Professional & scientific | 2024 |
| Smartchoice Driveways Ltd | Construction | 2021 |
| Smartcock UK Limited | Wholesale & retail | 2026 |
| Smartdo Ltd | Wholesale & retail | 2014 |
| Smarter Clicks Financial Services Ltd | Professional & scientific | 2017 |
| Smarthome Electrical Sevenoaks Limited | Manufacturing | 2021 |
| Smartstyle Interiors Limited | Other services | 2006 |
| Smile Outdoors Limited | Education | 2024 |
| Smiles Superfood Ltd | Wholesale & retail | 2013 |
| Smiley JIM Ltd | Professional & scientific | 2015 |
| Smith & Western (Addlestone) Limited | Hospitality | 2018 |
| Smith & Western (Boxhill) Limited | Hospitality | 2019 |
| Smith & Western (Chichester) Limited | Hospitality | 1997 |
| Smith & Western (Horsham) Limited | Hospitality | 2019 |
| Smith & Western (Tilgate) Ltd | Hospitality | 2011 |
| Smith & Western (Tunbridge Wells) Ltd | Hospitality | 2008 |
| Smith & Western Lingfield Ltd | Hospitality | 2007 |
| Smith & Western Restaurants Ltd | Hospitality | 2007 |
| Smith and Gale Therapy Limited | Health & social care | 2016 |
| Smith Promotions Ltd | Arts & recreation | 2026 |
| Smith's Patisserie Ltd | Manufacturing | 2026 |
| Smoke & Oakum Ltd | Hospitality | 2024 |
| Smoke Busters Ltd | Construction | 2024 |
| Snag-A-Bite Limited | Hospitality | 2024 |
| Snave Property Services Ltd. | Households | 2024 |
| SNC Cars Limited | Transport & logistics | 2003 |
| Snowfish Limited | Information & communication | 2021 |
| SO Sussex Limited | Hospitality | 2009 |
| Sob-Pol Ltd | Transport & logistics | 2022 |
| Social Fireworks Ltd. | Professional & scientific | 2017 |
| Social Value Network Limited | Professional & scientific | 2026 |
| Socialkomb Ltd | Information & communication | 2021 |
| Sociosell Ltd | Professional & scientific | 2023 |
| Soho Square Ltd. | Hospitality | 1998 |
| Sojorn CIC | Education | 2024 |
| Solar (LBP) Ltd. | Other services | 2021 |
| Solar Spectrum Limited | Construction | 2010 |
| Sole Memories Limited | Arts & recreation | 2012 |
| Soleil Marketing Ltd | Professional & scientific | 2023 |
| Solid Software Limited | Information & communication | 2010 |
| Solidbase Limited | Information & communication | 2001 |
| Soliser Global Limited | Wholesale & retail | 2012 |
| Solta Ltd | Manufacturing | 2026 |
| Soluble Limited | Wholesale & retail | 2013 |
| Solutions in Healthcare Limited | Health & social care | 2015 |
| Solutions Onchip Ltd | Manufacturing | 2018 |
| Somerhill Consulting Services Limited | Professional & scientific | 2007 |
| Songhurst Caravans Limited | Other services | 2002 |
| Sonrie Aesthetics Ltd | Health & social care | 2021 |
| Sophos Solutions Limited | Professional & scientific | 2024 |
| Soprano Property Ltd | Real estate | 2022 |
| Soprano Wine Bar Limited | Hospitality | 2006 |
| Sorg Limited | Health & social care | 2016 |
| Sorg Services Limited | Health & social care | 2021 |
| Sorrell Decorating Ltd | Construction | 2020 |
| Soteria Art Risk Management Ltd | Financial services | 2026 |
| Soulkit Ltd | Wholesale & retail | 2020 |
| Soulramen Ltd | Hospitality | 2026 |
| Sound ACT Ltd | Information & communication | 2019 |
| Sound Partner Limited | Information & communication | 2002 |
| Soundray Investments Limited | Real estate | 1996 |
| Souper Juice Limited | Hospitality | 2013 |
| Sourdough Camden Ltd | Hospitality | 2020 |
| South African Congregation | Other services | 2013 |
| South Court (Tunbridge Wells) Residents' Association Limited | Households | 1990 |
| South East Climbing Limited | Arts & recreation | 2013 |
| South East Homes and Land Ltd | Real estate | 2020 |
| South Frith Management Limited | Households | 1986 |
| South-East Rail Limited | Transport & logistics | 1994 |
| Southborough & District Wheelers Limited | Arts & recreation | 2022 |
| Southborough Court Management Company Limited | Households | 1961 |
| Southborough MOT Centre Limited | Wholesale & retail | 2000 |
| Southborough Pet Groomers Ltd | Other services | 2022 |
| Southeast Block Management Ltd | Real estate | 2010 |
| Southeastern Europe Power Limited | Energy | 2016 |