| Dunholm Capital Ltd | Professional & scientific | 2010 |
| Dunn Financial Management Limited | Financial services | 2017 |
| Dunorlan Buildings Residents Company Limited | Real estate | 2005 |
| Dunorlan Park Store Ltd | Wholesale & retail | 2023 |
| Dunstan Hill House Limited | Households | 2024 |
| Dunstan Road Management Company Limited | Households | 2008 |
| DUO Milia Design Ltd | Professional & scientific | 2025 |
| DUO Sound Research Ltd | Professional & scientific | 2023 |
| Dupen Ltd | Administrative & support | 2013 |
| Durfort UK Holdings Limited | Financial services | 2020 |
| Durnell Marketing Limited | Professional & scientific | 1996 |
| Durr and Company Ltd | Professional & scientific | 2010 |
| Dusklight Films Limited | Information & communication | 2008 |
| Dutton Properties Limited | Real estate | 2014 |
| Dutylinks Healthcare Ltd | Public administration | 2024 |
| Duxburys Solicitors Limited | Professional & scientific | 2010 |
| DV Rusholme Holdings Ltd | Financial services | 2024 |
| Dvkr Ltd | Information & communication | 2024 |
| DVN Holdings Limited | Financial services | 2006 |
| Dwhp Holdings Limited | Financial services | 2018 |
| Dwhp Limited | Construction | 2002 |
| DWM Developments (Kent) Limited | Construction | 2025 |
| Dynamic Air Engineering UK Limited | Manufacturing | 2009 |
| Dynamo Maritime Ltd | Public administration | 2026 |
| Dzuk Ltd | Financial services | 2015 |
| E K Nunn Ltd | Professional & scientific | 2024 |
| E M Poli Contracting Limited | Professional & scientific | 2015 |
| E-Tec Interconnect (UK) Limited | Manufacturing | 1993 |
| E.C. Parker & Company Limited | Financial services | 1949 |
| E.C.A Property Innovation Ltd | Administrative & support | 2023 |
| E.F.Guthrie Limited | Real estate | 1935 |
| E.R. Hickmott & SON Funeral Directors Limited | Other services | 2024 |
| E8T Developments Ltd | Information & communication | 2021 |
| Eagle & Woods Limited | Wholesale & retail | 2025 |
| Eagle View Homes Ltd | Real estate | 2024 |
| Eagles Leisure Limited | Arts & recreation | 2026 |
| Earlswood Chase Ltd | Financial services | 2024 |
| Early Edge Learning Ltd | Education | 2025 |
| Earth Island Publishing Limited | Information & communication | 2012 |
| Earthlight Ltd | Real estate | 2019 |
| Earthshine Ltd | Professional & scientific | 2023 |
| Easecommerce Ltd | Wholesale & retail | 2025 |
| East Natural Therapy Ltd | Health & social care | 2025 |
| East of England Regional Executive Limited | Other services | 2003 |
| East Point Management Company Limited | Households | 1991 |
| East Quay Boat Yard Ltd | Transport & logistics | 2023 |
| East Quay Boatyard Anchorage Ltd | Transport & logistics | 2026 |
| East West Ales Limited | Wholesale & retail | 1991 |
| Eastern Barn Limited | Hospitality | 2026 |
| Easy Reading Limited | Education | 2003 |
| Easybook Training Ltd | Professional & scientific | 2009 |
| Eazy Group Ltd | Wholesale & retail | 2023 |
| EB Design Management Ltd | Extraterritorial | 2012 |
| EBA Properties Ltd | Real estate | 2020 |
| Ebor Project Consultants Ltd | Professional & scientific | 2018 |
| Ebsworth Burgers Ltd | Hospitality | 2022 |
| Ec&I Management Limited | Professional & scientific | 2026 |
| Eclare Management Limited | Professional & scientific | 2016 |
| Eco Abode Ltd | Construction | 2020 |
| Eco Hideaways Ltd | Agriculture & fishing | 2022 |
| Ecogenica Ltd | Wholesale & retail | 2023 |
| Ecom Hub Ltd | Other services | 2019 |
| ECOM180 Ltd | Professional & scientific | 2024 |
| Econbadge Limited | Households | 1984 |
| Ecotrade Online Ltd | Wholesale & retail | 2026 |
| Edart Limited | Information & communication | 2000 |
| Edbury Estates Limited | Real estate | 1992 |
| Edcas Investments Limited | Administrative & support | 2013 |
| Eden B Studio Ltd | Wholesale & retail | 2022 |
| Eden Chase Management Limited | Households | 2010 |
| Eden House Residents Association Limited | Households | 1970 |
| EDEN22 Limited | Information & communication | 2020 |
| EDG IT Consulting Ltd | Information & communication | 2023 |
| Edition Design Limited | Construction | 2025 |
| Edmh Solutions Limited | Professional & scientific | 2020 |
| Edmondson Conservatories Limited | Construction | 2002 |
| Edmondsons Doors Ltd | Construction | 2022 |
| Edro Limited | Professional & scientific | 1995 |
| Edtech Experts Limited | Information & communication | 2019 |
| Eduan Weiss Limited | Real estate | 2015 |
| Education Advocacy Service Ltd | Other services | 2022 |
| Education Development Partnerships Limited | Professional & scientific | 2016 |
| Edugarden International Culture Exchange Co Ltd | Education | 2014 |
| Edutalent Group Ltd | Administrative & support | 2024 |
| Edward Shaw Ltd | Professional & scientific | 2022 |
| Edward Street Residents' Association Limited | Households | 1971 |
| EE Farming Ltd | Agriculture & fishing | 2025 |
| Efandef Ltd | Hospitality | 2025 |
| EFC Limited | Professional & scientific | 2005 |
| Effective Code Ltd | Professional & scientific | 2013 |
| Efsaas Limited | Information & communication | 2026 |
| Eglantine Catering Limited | Hospitality | 1994 |
| EHC Systems Limited | Extraterritorial | 2009 |
| Ehkq Propco Ltd | Real estate | 2020 |
| Eidos Advisory Ltd | Professional & scientific | 2013 |
| Eight Arms Limited | Information & communication | 2011 |
| Eight Plus Four Ltd | Professional & scientific | 2024 |
| EIS Software UK Ltd. | Information & communication | 2021 |
| Ekimetrics UK Limited | Professional & scientific | 2013 |
| EKR Lighting Limited | Administrative & support | 2014 |