| Riverside Melksham Ltd | Wholesale & retail | 2017 |
| Riverway MOT Centre Limited | Wholesale & retail | 2011 |
| RJ and Sons Tyres Ltd | Manufacturing | 2025 |
| RJ Properties (SW) Ltd | Real estate | 2025 |
| RNL Holdings Limited | Financial services | 2025 |
| Roadhog Catering Limited | Hospitality | 2014 |
| Roaming Events Ltd | Arts & recreation | 2022 |
| Roast ‘N’ Toast Ltd | Hospitality | 2024 |
| Robert Duncan Consultancy Limited | Professional & scientific | 2011 |
| Robinsons Traditional Fish and Chips (Hilperton) Limited | Real estate | 2012 |
| Robinsons Traditional Retail Limited | Hospitality | 2023 |
| Rochester Tate Ltd | Professional & scientific | 2008 |
| Rocks Bridge Limited | Wholesale & retail | 2023 |
| Rode Haulage Limited | Transport & logistics | 2006 |
| Rogers Poultry Services Limited | Agriculture & fishing | 2017 |
| Rolcor Investments Ltd | Financial services | 2018 |
| Rolcor Serviced Accommodation Ltd | Real estate | 2022 |
| Roman Bidco Limited | Wholesale & retail | 2015 |
| Roman Group Topco Limited | Wholesale & retail | 2015 |
| Roman West Interiors Limited | Construction | 2003 |
| Romney House Limited | Health & social care | 2013 |
| Rood Rampage Events Ltd | Professional & scientific | 2024 |
| Rooted Vegetarian Cafe Limited | Hospitality | 2018 |
| Rosewood 71 Limited | Real estate | 2017 |
| Ross Pike Heating Services Limited | Construction | 2019 |
| Ross Portfolio Management Limited | Real estate | 2016 |
| Roundstone Mews Management Company Limited | Households | 2018 |
| Roundstone Street Management Company Limited | Households | 2018 |
| ROYA1 Barber Shop Ltd | Other services | 2026 |
| Royanne Limited | Administrative & support | 2014 |
| RPM Home Renovation Limited | Construction | 2025 |
| RS Commercial Finance Limited | Financial services | 2021 |
| RS Food Services Limited | Hospitality | 2019 |
| Rsfa (UK) Ltd | Other services | 2020 |
| RSV Refinishers Limited | Wholesale & retail | 2002 |
| Ruari Mears Solutions Ltd | Professional & scientific | 2024 |
| Rudecki Property Ltd | Real estate | 2025 |
| Rumie Limited | Health & social care | 2021 |
| Rushmead Park Management Company Limited | Households | 2005 |
| Russell Whatley Heating Services Limited | Construction | 2017 |
| Rusty Cactus Holdings Limited | Financial services | 2025 |
| S D Instrumentation Limited | Manufacturing | 2007 |
| S F J Software Limited | Extraterritorial | 2012 |
| S T Body Repairs Limited | Wholesale & retail | 2012 |
| S Z Electrical Limited | Construction | 2014 |
| S&A Unigardens Ltd | Construction | 2015 |
| S&C International Logistics Ltd | Transport & logistics | 2020 |
| S&J Property Group (South West) Ltd | Real estate | 2025 |
| S&M Auto Solution Ltd | Wholesale & retail | 2025 |
| S. Simmonds & SON Limited | Wholesale & retail | 1972 |
| S.Harper Vision Limited | Health & social care | 2014 |
| S.J. Gibbins Limited | Construction | 1999 |
| S.K.Fruits Limited | Wholesale & retail | 1983 |
| S7VEN Group Ltd | Professional & scientific | 2022 |
| SA Group Ltd | Information & communication | 2009 |
| SA Group Trustees Limited | Administrative & support | 2021 |
| Safe Care (Wiltshire) Limited | Extraterritorial | 2010 |
| Safety on Site Compliance Limited | Construction | 2017 |
| Saffin Hygiene Ltd | Wholesale & retail | 2015 |
| Sage Tuition Ltd | Education | 2026 |
| Saint Augustine's Catholic College | Education | 2011 |
| Salter House Management Company Limited | Real estate | 2000 |
| Saltus Trustees Limited | Extraterritorial | 2017 |
| SAM Allison Official Consultancy Limited | Professional & scientific | 2025 |
| Samrex Ltd | Wholesale & retail | 2026 |
| Sandridge House Melksham Resident's Association Limited | Households | 1969 |
| Sandringham Properties Limited | Hospitality | 2017 |
| Sandwick Consulting Limited | Real estate | 2016 |
| Sara Home Ltd | Real estate | 2017 |
| Saren Limited | Health & social care | 2006 |
| Sass Circus Ltd | Arts & recreation | 2022 |
| Sass Events Ltd | Arts & recreation | 2021 |
| Saxon Mews Limited | Households | 2006 |
| Scarlet Seaward Limited | Information & communication | 2011 |
| Schneider Design Ltd | Professional & scientific | 2020 |
| Scitec Instruments Limited | Manufacturing | 1980 |
| Scorestone Limited | Professional & scientific | 2024 |
| Scott ALL Electrical Ltd | Construction | 2025 |
| Scott Portsmouth Ltd | Construction | 2014 |
| Scotties Hair Designs Limited | Other services | 2010 |
| Scout and Sage Spirits Limited | Manufacturing | 2016 |
| SD Construction Ltd | Real estate | 2018 |
| Sea Export Limited | Wholesale & retail | 2017 |
| Sea Site Investment Ltd | Real estate | 2021 |
| Seagrove Bay Ltd | Extraterritorial | 2023 |
| Seahawk Marine Foods (London) Limited | Wholesale & retail | 2007 |
| Seahawk Seafoods Limited | Extraterritorial | 2003 |
| Seating Services Limited | Manufacturing | 2008 |
| SEB Transportation Ltd | Transport & logistics | 2018 |
| Second Mountain Comms Ltd | Professional & scientific | 2020 |
| Sedcomm Limited | Administrative & support | 2011 |
| Selwood Devco Limited | Construction | 2014 |
| Selwood Housing Society Limited | Real estate | 2001 |
| Sendnest Limited | Information & communication | 2026 |
| Sensibly Priced Performance Ltd | Manufacturing | 2020 |
| Sensorimotor Psychotherapy United Kingdom Ltd | Education | 2025 |
| Seven Media Group Ltd | Information & communication | 2018 |
| Seven Smile Limited | Health & social care | 2023 |
| Severn James Recruitment Ltd | Administrative & support | 2024 |
| Severnside 268 Limited | | 1992 |