| Reach Access Services Ltd | Construction | 2025 |
| Realms Seed AI Ltd | Information & communication | 2025 |
| Reframe & Regulate Ltd | Health & social care | 2026 |
| Reilly&Co Ltd | Professional & scientific | 2025 |
| Retail Stocktaking Ltd. | Administrative & support | 2008 |
| Reywood Construction Limited | Construction | 1989 |
| RF Slight Joinery Ltd. | Construction | 2010 |
| RF Slight Property Ltd. | Real estate | 2014 |
| RF Slight Timber Supplies Ltd. | Manufacturing | 2014 |
| Rhet Lothian | Education | 2002 |
| Richard Mein Wealth Management Ltd | Professional & scientific | 2021 |
| RK Business Ltd | Hospitality | 2024 |
| Rmgc Holdings Ltd | Professional & scientific | 2024 |
| Rogerson Coach Travel Limited | Transport & logistics | 2019 |
| Romtex Limited | Information & communication | 2004 |
| Rongna Trading Limited | Wholesale & retail | 2025 |
| Rosearista Ltd | Hospitality | 2020 |
| Rosehip Hideaway Ltd | Hospitality | 2020 |
| RS Crew Ltd | Construction | 2025 |
| RV Autos Limited | Wholesale & retail | 2014 |
| S J Armstrong Consulting Ltd | Information & communication | 2020 |
| S-Move Removals Ltd | Transport & logistics | 2026 |
| S-Move Technologies Ltd | Information & communication | 2026 |
| Sailors Sea Salt Ltd | Manufacturing | 2026 |
| Saint Gabriel Events Ltd | Hospitality | 2020 |
| Saltire Rental Solutions Limited | Construction | 2023 |
| Saltire Team Gymnastics | Arts & recreation | 2016 |
| Saorsa Ltd | Information & communication | 2017 |
| Saqiearth Consultancy Ltd | Extraterritorial | 2024 |
| Sbtp Properties Limited | Construction | 2010 |
| Scholarland Ltd | Information & communication | 2019 |
| Scot Chip Limited | Manufacturing | 2003 |
| Scotia Facilities Ltd | Administrative & support | 2023 |
| Scots Auto Electrics Ltd | Wholesale & retail | 2021 |
| SDH Plant Hire Ltd | Administrative & support | 2023 |
| Seacliff Building Ltd | Construction | 2021 |
| Seaview Developments (Edinburgh) Ltd. | Construction | 2015 |
| Sensoar Limited | Professional & scientific | 2024 |
| Sharon Ahern Ltd | Administrative & support | 2024 |
| Shoreside Services Limited | Financial services | 2022 |
| SJ Lothian Ltd | Professional & scientific | 2025 |
| SJS Macmerry Flyer Driver Hire Ltd | Construction | 2025 |
| Skyline Dwellings Ltd | Real estate | 2025 |
| Skyrise Civils Ltd | Administrative & support | 2025 |
| Slate Surgeons Ltd | Construction | 2022 |
| Smart Build Edinburgh Limited | Construction | 2025 |
| Smooth Competitions Ltd | Wholesale & retail | 2025 |
| SN Edin Ltd | Health & social care | 2022 |
| Soccer Stars Academy Aberdeen Ltd | Arts & recreation | 2022 |
| Soccer Stars Academy Lothians & Borders Ltd | Education | 2023 |
| Sojam Consulting Limited | Information & communication | 2024 |
| Solid Install Ltd | Construction | 2023 |
| Sons Pubs Limited | Hospitality | 2025 |
| Soul Motive Events Ltd | Hospitality | 2026 |
| Sound Bath Studio Ltd | Health & social care | 2025 |
| Spark Building Solutions Ltd | Construction | 2019 |
| Sparkles Hand Car Wash East Lothian Ltd | Administrative & support | 2018 |
| Spectrum Data Limited | Information & communication | 2016 |
| SRJ Developments Ltd | Construction | 2026 |
| SRJ Joiners Ltd | Construction | 2018 |
| ST Gabe Limited | Professional & scientific | 2011 |
| Steven Gain Electrical Limited | Construction | 2021 |
| STF Networks Ltd | Information & communication | 2017 |
| Stoneyburn Healthcare Limited | Wholesale & retail | 2006 |
| STR House Clearances Limited | Transport & logistics | 2024 |
| Student Pack and Store Ltd | Transport & logistics | 2024 |
| Studiocreates Design Ltd | Professional & scientific | 2025 |
| Sumac Taxis Limited | Professional & scientific | 2000 |
| Sunamp Limited | Professional & scientific | 2005 |
| Sunrise Development Services Ltd | Construction | 2022 |
| Sweet Haven of Tranent Ltd | Hospitality | 2016 |
| T & J Wallace Repair and Recovery Limited | Wholesale & retail | 2010 |
| Taigh Ltd | Real estate | 2017 |
| Taigh Property Investments Ltd | Real estate | 2025 |
| Task Technology (Scotland) Limited | Professional & scientific | 1991 |
| Tasty Cafe Glasgow Limited | Hospitality | 2019 |
| Tay-City Properties Limited | Construction | 1999 |
| Taylan Kennels Ltd | Agriculture & fishing | 2025 |
| TC Events Consultancy Limited | Arts & recreation | 2006 |
| THE Bubble Lounge Ltd | Other services | 2025 |
| THE BUS Stop Ltd | Hospitality | 2017 |
| THE Deodoriser Ltd | Wholesale & retail | 2012 |
| THE Edinburgh Natural Skincare Company (Retail Shops) Limited | Manufacturing | 2010 |
| THE Edinburgh Natural Skincare Company Limited | Other services | 2013 |
| THE HQ TP Ltd | Other services | 2022 |
| THE Old Sawmill Limited | Real estate | 2006 |
| THE Pink Roofer Ltd | Construction | 2020 |
| THE Playbark Ltd | Other services | 2023 |
| THE Potter’S HUT Limited | Arts & recreation | 2026 |
| THE Virtual Miracle Company Limited | Information & communication | 2008 |
| THE Wallpaper Company Limited | Wholesale & retail | 2024 |
| Theheat Ltd | Construction | 2008 |
| Thistle Bar Solutions Ltd | Hospitality | 2019 |
| Thistle Floors Ltd | Construction | 2025 |
| Thomas Crooks Global Ltd | Administrative & support | 2024 |
| Thon Solutions Ltd | Professional & scientific | 2022 |
| Thorburn Joinery Limited | Construction | 2025 |
| Thorburn Roofing and Building Ltd | Professional & scientific | 2019 |
| Tillcroft Ventures L.P. | | 2009 |
| Timber Bush Associates Ltd. | Professional & scientific | 1997 |