| Resolute Heating Solutions Ltd. | Construction | 2022 |
| Retinaspecialist Limited | Health & social care | 2011 |
| Reussir Enterprises Limited | Real estate | 2004 |
| Reynolds Rescue & Recovery Ltd | Transport & logistics | 2021 |
| RFT Equine Ltd | Agriculture & fishing | 2026 |
| Rhino Academy Ltd | Education | 2026 |
| Rhino Construction Solutions Ltd | Construction | 2019 |
| Rhino Plumbing Ltd | Construction | 2022 |
| Rhino Sports Academy Limited | Arts & recreation | 2019 |
| Rhino Waste Machinery Ltd | Manufacturing | 2026 |
| Rhubarb FOX Limited | Administrative & support | 2012 |
| Rice & Curry House Limited | Hospitality | 2024 |
| Richard Baker Limited | Real estate | 2014 |
| Richard Horsley & Co Limited | Professional & scientific | 1997 |
| Richmond Road (Freehold) Management Company Limited | Extraterritorial | 2015 |
| Rickeast Group Ltd | Transport & logistics | 2024 |
| Ridge Crest Consulting Limited | Information & communication | 2025 |
| Rignall Farm Livery Limited | Agriculture & fishing | 2015 |
| Rise & Grind Fitness Ltd | Wholesale & retail | 2023 |
| Risk Assessment Associates Limited | Professional & scientific | 2001 |
| River ODP Ltd | Construction | 2022 |
| Riverine Limited | Professional & scientific | 2016 |
| Riverside Tennis Club Limited | Arts & recreation | 2026 |
| Rivista Group Limited | Information & communication | 2024 |
| Rixille Clothing Company Ltd | Wholesale & retail | 2025 |
| RKF Investment Company | Financial services | 2019 |
| RMS Commercial Landscapes Limited | Administrative & support | 2022 |
| Roaz Ltd | Real estate | 2025 |
| Robertson Ness Limited | Professional & scientific | 2013 |
| Robertsons Consulting Ltd | Professional & scientific | 2010 |
| Robinson Fields Ltd | Real estate | 2019 |
| Rocco & Co. Hairdressing Ltd | Other services | 2010 |
| Rockall Holdings Limited | Financial services | 2020 |
| Rois Indelible Ltd | Wholesale & retail | 2024 |
| Roka Civils Limited | Construction | 2023 |
| Rollaz & Movaz Ltd | Manufacturing | 2026 |
| Rollmop Designs Limited | Professional & scientific | 2017 |
| Room to Relax Limited | Other services | 2012 |
| Root Investments Ltd | Real estate | 2019 |
| Rose & Daisy Properties Ltd | Real estate | 2016 |
| Rosemullion Investments Ltd | Real estate | 2024 |
| Roseth Ltd | Professional & scientific | 2016 |
| Ross Osborne Group Ltd | Financial services | 2015 |
| Rothbury Grove Ltd | Administrative & support | 2024 |
| Rotzler (U.K.) Limited | Wholesale & retail | 1980 |
| Rozo Real Estate Limited | Real estate | 2021 |
| Rpgl Bards Walk Ltd | Real estate | 2020 |
| Rpgl Carrs Lane Ltd | Real estate | 2025 |
| Rpgl Digbeth Ltd | Real estate | 2023 |
| Rpgl Eyre Street Ltd | Construction | 2024 |
| Rpgl Holdco Ltd | Financial services | 2023 |
| RSG Carpentry & Building Ltd | Manufacturing | 2025 |
| Rubicbit Ltd | Information & communication | 2021 |
| Rudolf Steiner College Limited | Extraterritorial | 2018 |
| Run & GUN Media Holdings Limited | Real estate | 2023 |
| Run & GUN Media Limited | Information & communication | 2016 |
| Russell & Sons Roofing Contractors Ltd | Extraterritorial | 2013 |
| Russell Reptiles Ltd | Wholesale & retail | 2012 |
| RZA Consultancy Ltd | Professional & scientific | 2024 |
| S & W Funerals Ltd | Other services | 2015 |
| S J E Commercial Services Ltd | Wholesale & retail | 2022 |
| S J Williams Transport Limited | Transport & logistics | 2021 |
| S&J Ceramic Tiling Limited | Construction | 2010 |
| S&S Lettings & Sales Ltd | Real estate | 2019 |
| S. Daveson Meats Ltd | Wholesale & retail | 2001 |
| SA Projects Limited | Arts & recreation | 2011 |
| Sa.Ab Developments Ltd | Manufacturing | 2019 |
| Safebydesign Ltd | Professional & scientific | 2007 |
| Safety Steps Ltd | Administrative & support | 2025 |
| Saleskick Consulting Ltd | Information & communication | 2021 |
| SALON58 Ltd | Wholesale & retail | 2025 |
| Sanctuary Homes R2R Ltd | Real estate | 2024 |
| Sandwell UK Holdings Limited | Manufacturing | 2021 |
| Sandwell UK Limited | Manufacturing | 2001 |
| Sanital Medical Ltd | Professional & scientific | 2020 |
| Sapling Consulting Ltd | Information & communication | 2009 |
| Sarah Glover Consulting Limited | Professional & scientific | 2023 |
| Sarju Mehta Limited | Health & social care | 2024 |
| Sarsen Group Ltd | Wholesale & retail | 2025 |
| Savience Limited | Information & communication | 2001 |
| Savvy Lets Ltd | Administrative & support | 2013 |
| Savvy Storage Ltd | Transport & logistics | 2017 |
| Sb&As Properties Ltd | Real estate | 2018 |
| SC Holdings (Northampton) Limited | Professional & scientific | 2024 |
| Scarlet HR Consulting Limited | Administrative & support | 2014 |
| Scarlets (Properties) Limited | Professional & scientific | 2019 |
| SCI Northampton Ltd | Construction | 2022 |
| Sconey Finance Ltd | Professional & scientific | 2008 |
| SE Traders Limited | Wholesale & retail | 2021 |
| Sea Reach Services Ltd | Professional & scientific | 2018 |
| Seamless Digital Holdings Limited | Financial services | 2023 |
| Seamless Digital Ltd | Information & communication | 2022 |
| Sean Finnegan Associates (Expert Witness) Limited | Other services | 2020 |
| Seawell Grounds Limited | Agriculture & fishing | 1981 |
| Secondi Limited | Professional & scientific | 2026 |
| Sejat Ltd | Information & communication | 2017 |
| Selby Barns Commercial Estate Limited | Construction | 2014 |
| Select Groundworks Ltd | Other services | 2018 |
| Self Storage Towcester Ltd | Real estate | 2019 |
| Senator Towcester Limited | Households | 1987 |