| Totnes Kayaks Limited | Other services | 2009 |
| Totnes Mill Lane Management Limited | Households | 2014 |
| Totnes Physio Clinic Limited | Health & social care | 2025 |
| Totnes Progressive School Ltd | Education | 2014 |
| Totnes Rugby Football Club (Trading) Limited | Arts & recreation | 2016 |
| Totnes Rugby Football Club Limited | Arts & recreation | 2016 |
| Totnes School of Guitar Making Limited | Education | 2002 |
| Totnes Tile and Bath Limited | Wholesale & retail | 2014 |
| Totnes Trust | Administrative & support | 1985 |
| Totnes Vape Co Ltd | Wholesale & retail | 2021 |
| Totnes Wine and Fine Food Ltd | Wholesale & retail | 2024 |
| Town Anywhere C.I.C. | Arts & recreation | 2025 |
| Townsend Developments (Devon) Limited | Construction | 2015 |
| TQ Print & Design Limited | Manufacturing | 2017 |
| TQ9 Partnership LLP | | 2006 |
| TQF Limited | Financial services | 2018 |
| Trading Cards Galore Ltd | Wholesale & retail | 2023 |
| Training Hand Limited | Education | 1996 |
| Transfixus Creative Ltd | Information & communication | 2025 |
| Transformedia Culture C.I.C. | Information & communication | 2011 |
| Transition Homes Community Land Trust | Construction | 2011 |
| Transition Town Totnes Ltd | Other services | 2007 |
| Traumatology Ltd | Health & social care | 2023 |
| Treasure Trove Traders Limited | Wholesale & retail | 2025 |
| Tregaron Management Company Limited | Households | 1993 |
| Tregelles and Seager Limited | Construction | 2007 |
| Trehane Farms Ltd. | Agriculture & fishing | 1989 |
| Triambic Ltd | Financial services | 2025 |
| Triformis Limited | Professional & scientific | 2008 |
| True Street House Management Company Limited | Administrative & support | 2011 |
| Ttkb Limited | Wholesale & retail | 2021 |
| Tuna Gear UK Ltd | Wholesale & retail | 2022 |
| Turbo ZEN Ltd | Professional & scientific | 2018 |
| Tushingham Sails Limited | Extraterritorial | 2016 |
| Tushingham Sales Limited | Wholesale & retail | 2016 |
| Two Potts LLP | | 2025 |
| Two Swallows Properties Ltd | Financial services | 2023 |
| Tyrrell Sports Coaching and Education Ltd | Arts & recreation | 2017 |
| UK History Finders Ltd | Other services | 2019 |
| UK Innovation Pioneers Limited | Professional & scientific | 2018 |
| UK Sire Services Limited | Agriculture & fishing | 2001 |
| Umbel Studios Ltd | Professional & scientific | 2022 |
| Uncle Matt’S Limited | Wholesale & retail | 2023 |
| UNI Stewards Ltd | Administrative & support | 2023 |
| Uni-Thread Limited | Wholesale & retail | 2003 |
| UNO Street Foods Co Ltd | Hospitality | 2025 |
| Untangle Education CIC | Education | 2023 |
| Upton Property Limited | Real estate | 2017 |
| Valhalla Garden Care Ltd | Administrative & support | 2020 |
| Valley Enterprises (SW) Limited | Real estate | 2004 |
| Vanbeekdodge Complex Care Ltd | Health & social care | 2021 |
| Velatrix Limited | Real estate | 2012 |
| Venton Court Management Limited | Households | 2003 |
| Venton Enterprises Limited | Arts & recreation | 2012 |
| Venturi Film Factual Ltd | Information & communication | 2021 |
| Venturi Film Ltd | Information & communication | 2019 |
| Veon Ltd | Construction | 2013 |
| Veracity Trading Limited | Manufacturing | 2009 |
| VHL Accounting Ltd | Professional & scientific | 2014 |
| Vian Marketing Limited | Professional & scientific | 2015 |
| Vikas Bloom | Education | 2025 |
| Viking NU Limited | Wholesale & retail | 2008 |
| Village Makers Developments Limited | Real estate | 2016 |
| Vineyard Property Management Company Limited | Real estate | 2012 |
| Vire Engineering Limited | Manufacturing | 1987 |
| Virtual Insurance Products Limited | Financial services | 2001 |
| Visyoo Ltd | Information & communication | 2020 |
| Vita Revive Ltd | Other services | 2025 |
| Vocal Advocacy | Other services | 2006 |
| Voco Veritas Consulting Ltd | Information & communication | 2018 |
| W G F & D W Hunt Ltd | Agriculture & fishing | 2016 |
| W R Frost & Co Limited | Professional & scientific | 2005 |
| Wallis & Beard Ltd | Construction | 2001 |
| Wan-Ai Ltd | Information & communication | 2019 |
| Warrenfield Property Limited | Real estate | 2017 |
| Watch House Devon Limited | Hospitality | 2025 |
| Waterborn Hub CIC | Arts & recreation | 2025 |
| Waterhead Projects Limited | Construction | 2017 |
| Waterman Tree Company Limited | Administrative & support | 2022 |
| Watermans Arms PUB Company Ltd | Hospitality | 2025 |
| Waters Reach (Staverton) Limited | Real estate | 2007 |
| WE ARE Grounded Ltd | Professional & scientific | 2026 |
| Webselect Limited | Administrative & support | 1998 |
| Weheartdigital Ltd | Information & communication | 2011 |
| Wellgevity Limited | Health & social care | 2018 |
| Wellington Pet (Devon) Limited | Wholesale & retail | 2017 |
| West Hartley Management Company Limited | Households | 2005 |
| Westlands Transport Limited | Transport & logistics | 2021 |
| Weston House (Berry Pomeroy) Management Company Limited | Households | 2004 |
| Whitch Developments Ltd | Real estate | 2023 |
| White Parks Management Company Limited | Households | 2024 |
| Widdington Hydro Ltd | Energy | 2016 |
| Wild Embers CIC | Education | 2017 |
| Wild Running Limited | Arts & recreation | 2015 |
| Wildthings Pictures Ltd | Information & communication | 2025 |
| Wildwise Events Limited | Education | 1999 |
| Wiljam Ltd | Professional & scientific | 2023 |
| Will Hoare Architect Ltd | Professional & scientific | 2016 |
| William Joshua Templeton Limited | Agriculture & fishing | 2021 |
| William Lana Limited | Financial services | 2013 |