| Pretreat Ltd | Wholesale & retail | 2006 |
| Pretty Real Ltd | Real estate | 2025 |
| Primrose Bank Holidays Limited | Hospitality | 2018 |
| Print Media Quality Ltd | Professional & scientific | 2019 |
| Printservedigital Limited | Manufacturing | 2016 |
| Prinz Environmental Services Limited | Professional & scientific | 2019 |
| Prinz Limited | Professional & scientific | 2007 |
| Pristinedent Ltd | Wholesale & retail | 2024 |
| Private ERA Limited | Wholesale & retail | 2020 |
| Professional Motorsports Limited | Arts & recreation | 2007 |
| Proflow M&E Limited | Construction | 2024 |
| Promopluse Printers Ltd | Professional & scientific | 2025 |
| Protravel Solutions Ltd | Administrative & support | 2025 |
| PTD Civils Limited | Construction | 2025 |
| Puig Puig Puig Limited | Real estate | 2022 |
| Pure Heat Pumps Ltd | Construction | 2020 |
| Pure Life Records Ltd | Information & communication | 2018 |
| Purus Homes Ltd | Construction | 2026 |
| Q & S Restaurant Ltd | Hospitality | 2024 |
| Q Hotel Todmorden Ltd | Hospitality | 2022 |
| Quadrivium Developments Limited | Construction | 2022 |
| Quiddlesticks Ltd | Arts & recreation | 2024 |
| R.A.E Roofing & Building Services Ltd | Construction | 2026 |
| Ramsden Training Limited | Education | 2025 |
| Randles Collection Travel Agency Ltd | Administrative & support | 2025 |
| Ranjit Technology & Computer Services Ltd | Information & communication | 2023 |
| Razaq Plumbing Limited | Construction | 2024 |
| Recycling Organisation for Research Opportunities | Manufacturing | 2009 |
| Reed Studio Limited | Professional & scientific | 2019 |
| Rendezvous Bistro Hebden Bridge Limited | Hospitality | 2023 |
| Revita Automation Limited | Manufacturing | 2013 |
| Revocation Limited | Professional & scientific | 1990 |
| Revolution 21 Ltd | Other services | 2025 |
| Richard Coupe Limited | Real estate | 1927 |
| Rigomi Ltd | Information & communication | 2020 |
| Rilysio Limited | Hospitality | 2020 |
| RK Consulting 2017 Limited | Administrative & support | 2017 |
| RML Associates Limited | Financial services | 2026 |
| Robert Coxon Limited | Construction | 2011 |
| Robinwood (EOT) Limited | Financial services | 2024 |
| Robinwood Electrical Services Limited | Construction | 2006 |
| Robinwood Interiors Ltd | Manufacturing | 2022 |
| Robinwood Property Limited | Real estate | 2021 |
| Roch Valley Lettings Limited | Real estate | 2019 |
| Roch Valley Self Storage Ltd | Other services | 2005 |
| Rock END Moor Gritstone Company Limited | Mining & quarrying | 2011 |
| Rock N Roll Beds.Com Ltd | Manufacturing | 2011 |
| Rooftop Investments Limited | Hospitality | 2004 |
| Rooms Todmorden Ltd | Wholesale & retail | 2023 |
| Rooting 4 Change | Agriculture & fishing | 2025 |
| Rosiemorrissey Ltd | Administrative & support | 2019 |
| Royd Farm Ltd | Real estate | 2025 |
| RS Asbestos Ltd | Construction | 2011 |
| S & a Private Limited | Hospitality | 2018 |
| S C Pipelines Ltd | Wholesale & retail | 2013 |
| S I International (UK) Limited | Information & communication | 2001 |
| S I K Car Sales Ltd | Wholesale & retail | 2026 |
| S M C Solutions Ltd | Information & communication | 2022 |
| S&A Meats Ltd | Wholesale & retail | 2023 |
| Saaslife Ltd | Administrative & support | 2023 |
| Sacred Cacao Path Community Interest Company | Health & social care | 2025 |
| Safe Heaven Organization Ltd | Administrative & support | 2024 |
| Safespaces (Cornholme) Limited | Manufacturing | 2006 |
| SAI27 Ltd | Hospitality | 2025 |
| Saker Vegetarian Foods Limited | Manufacturing | 1997 |
| Sakura Dental Ltd | Health & social care | 2022 |
| SAM Ablitt Fire Engineering Ltd | Professional & scientific | 2025 |
| Sandtree Limited | Real estate | 1976 |
| Sarah Dudley Ltd | Professional & scientific | 2010 |
| SARDAR143 Ltd | Wholesale & retail | 2025 |
| Saul Caldwell Limited | Professional & scientific | 2012 |
| School for Sustainable Living CIC | Education | 2021 |
| Scott Lowe Design Ltd | Manufacturing | 2005 |
| Search Mortgage Solutions Ltd | Extraterritorial | 2010 |
| Seloria Limited | Wholesale & retail | 2025 |
| Sensepack Ltd | Administrative & support | 2019 |
| Serenum Labs Ltd | Information & communication | 2025 |
| SF Real Ltd | Construction | 2022 |
| Shangrella Ltd | Hospitality | 2018 |
| Shaw Farm Equestrian Limited | Arts & recreation | 2014 |
| Shaw Farm Liveries Limited | Arts & recreation | 2014 |
| Shaw Farm Training Ltd | Other services | 2025 |
| Shephard & Moyes Limited | Professional & scientific | 2012 |
| Shurcrack Farm Limited | Agriculture & fishing | 2021 |
| Sibyls Properties Limited | Real estate | 2022 |
| Siloxycoat Limited | Extraterritorial | 2013 |
| Silverene Administration Ltd | Information & communication | 2014 |
| Singletrack Media Limited | Information & communication | 2014 |
| Site Restaurant Limited | Hospitality | 2014 |
| SK Excel Dental Limited | Health & social care | 2008 |
| Skatecamp CIC | Education | 2025 |
| Skhan Printing Ltd | Other services | 2022 |
| Slevnatics Ltd | Administrative & support | 2019 |
| Slipcrotire Ltd | Wholesale & retail | 2019 |
| Slyfias Ltd | Wholesale & retail | 2019 |
| Smartsight Business and Executive Consulting & Business Coaching Limited | Professional & scientific | 2022 |
| SMK Building & Joinery Contractors Ltd | Construction | 2015 |
| SMK Joinery Ltd | Manufacturing | 2023 |
| Smooth Mobility Ltd | Wholesale & retail | 2025 |
| Softnot Limited | Information & communication | 2015 |