| Programme Management Solutions Limited | Information & communication | 2000 |
| Protectaseal Limited | Manufacturing | 1994 |
| Puffer Properties Ltd | Real estate | 2026 |
| Pure Cleans Devon Ltd | Administrative & support | 2026 |
| Pyza Shop Ltd | Wholesale & retail | 2026 |
| Qualitrade Global Ltd | Wholesale & retail | 2026 |
| Quantum Games Studio Ltd | Information & communication | 2025 |
| Quarrymans Management Company Bampton Limited | Real estate | 2019 |
| R Diggle Electrical Ltd | Construction | 2026 |
| R J Mccabe Ltd | Real estate | 2024 |
| R M Property (SW) Ltd | Real estate | 2024 |
| R W Estates (Trading) Limited | Real estate | 1999 |
| R W Estates Ltd | Real estate | 1966 |
| R W Patterns Ltd | Manufacturing | 2015 |
| R. Dennis (General Builder) Limited | Construction | 2006 |
| R.T.R. Services Limited | Manufacturing | 1999 |
| Rackenford Construction Limited | Extraterritorial | 2016 |
| Radfords Fine Fudge Limited | Manufacturing | 2006 |
| Radnidge Farm Limited | Agriculture & fishing | 1965 |
| Rainbow Heat & Power Limited | Construction | 2013 |
| Rapid Edging Limited | Other services | 2009 |
| RAS Scaffolding (SW) Ltd | Construction | 2026 |
| Rawflow Barbers Ltd | Wholesale & retail | 2024 |
| RBF Holdings Limited | Financial services | 2018 |
| RC Construction South West Limited | Construction | 2021 |
| RC Doors and Shutter Solutions Ltd | Construction | 2025 |
| RCP South West Ltd | Real estate | 2026 |
| Reaper Cable Ltd | Wholesale & retail | 2020 |
| Recruitment Unlimited (SW) Ltd | Administrative & support | 2024 |
| Red Dragon Chinese Restaurant Ltd | Hospitality | 2022 |
| Redarbor Limited | Extraterritorial | 2013 |
| Redbrook Management Limited | Administrative & support | 2012 |
| Redlands Commercial Limited | Professional & scientific | 2012 |
| Redmax Speed Shop Ltd | Professional & scientific | 2013 |
| Refa Ltd | Hospitality | 2025 |
| Reflotec Solutions Ltd | Manufacturing | 2022 |
| Regal Trans Ltd | Transport & logistics | 2020 |
| Regency Properties (Tadworth) Limited | Real estate | 1980 |
| Regency Renovations (UK) Limited | Construction | 2009 |
| Rekindle Recovery CIC | Education | 2024 |
| Renewable Heat & Power Limited | Professional & scientific | 1999 |
| Replace a Part Limited | Wholesale & retail | 2000 |
| Rerooted Alternative Provision Ltd | Education | 2026 |
| Retail Computer Services Limited | Extraterritorial | 1983 |
| Retail Research & Development Limited | Information & communication | 1984 |
| Rexa Care Ltd | Administrative & support | 2026 |
| RG Process Ltd | Transport & logistics | 2020 |
| RGH Site Engineering Ltd | Professional & scientific | 2017 |
| RH Performance Ltd | Wholesale & retail | 2018 |
| Richard Allan London Limited | Wholesale & retail | 2018 |
| Richard Allan Scarves Limited | Arts & recreation | 2012 |
| Richard J Cole Transport Ltd | Transport & logistics | 2011 |
| Richmond Hill ( Properties ) Ltd | Real estate | 2019 |
| Ringstone Properties Limited | Hospitality | 2018 |
| Rivels Green Management Company Limited | Households | 2015 |
| Rivermead Dairy Limited | Wholesale & retail | 2016 |
| Riverside Sporting Limited | Arts & recreation | 2022 |
| RJM (Devon) Limited | Construction | 2015 |
| RJW Plumbing Supplies and Building Supplies Limited | Wholesale & retail | 2013 |
| RLG Lettings Limited | Real estate | 2021 |
| ROB Nicholls Limited | Professional & scientific | 2019 |
| Robert ANN Ltd | Real estate | 2025 |
| Robertcollom Ltd | Wholesale & retail | 2025 |
| Robur (SW) Limited | Agriculture & fishing | 2012 |
| Rock and Roll Transport Ltd | Transport & logistics | 2015 |
| Rocket & Rose Ltd | Manufacturing | 2012 |
| Rocknroll Jivetime Promotions Limited | Arts & recreation | 2020 |
| ROD Millman Racing Limited | Agriculture & fishing | 2002 |
| Roger Simmons Carpentry Limited | Construction | 2018 |
| Roland, Scott and White Properties Ltd | Real estate | 2022 |
| Romantica of Devon (Holdings) Ltd | Financial services | 2022 |
| Romantica of Devon Limited | Wholesale & retail | 1983 |
| Roofing Supplies (SW) Limited | Wholesale & retail | 2010 |
| Rooke Holt Limited | Professional & scientific | 1999 |
| Roots Systems Group Limited | Financial services | 2025 |
| Roots Systems Holdings Limited | Real estate | 2024 |
| Roots Systems Limited | Manufacturing | 1982 |
| Rose ASH Agricultural Limited | Agriculture & fishing | 2007 |
| Rose Hope Publishing Limited | Information & communication | 2022 |
| Rosebank Property Management Limited | Households | 1991 |
| Rotolok (Holdings) Limited | Manufacturing | 1974 |
| Rotolok Group Limited | Financial services | 2024 |
| Rotolok Limited | Manufacturing | 1986 |
| Roundtable Digital Ltd | Information & communication | 2024 |
| Rowe Office Ltd | Professional & scientific | 2026 |
| RR International Consulting Limited | Professional & scientific | 2013 |
| RS Landscape Design & Construction Ltd | Administrative & support | 2020 |
| Rspd Management Company Limited | Real estate | 2013 |
| Rumsam Meadows Management Company Limited | Real estate | 2012 |
| Rushe Consulting Ltd | Administrative & support | 2025 |
| Rushton Classic Engineering Ltd | Wholesale & retail | 2023 |
| Russh Limited | Wholesale & retail | 2025 |
| Ruxley Fields Limited | Other services | 2000 |
| S a International Shipping Ltd | Transport & logistics | 2012 |
| S J Kenshole Plastering Ltd | Construction | 2015 |
| S Key Plumbing & Heating Limited | Construction | 2010 |
| S Land Electrical Services Limited | Construction | 2013 |
| S M V Associates Limited | Professional & scientific | 2003 |
| S N Pictures Ltd. | Other services | 2011 |
| S&M Garage Services Ltd | Wholesale & retail | 2019 |