| Sheco Developments Limited | Construction | 2019 |
| Sheco Engineering Services Limited | Construction | 1983 |
| Sheco Group Limited | Extraterritorial | 1999 |
| Sheco Renewable Systems Limited | Manufacturing | 2014 |
| Sherry Nailz Limited | Other services | 2026 |
| Shifnal Balti House Ltd | Hospitality | 2024 |
| Shikishi Bijutsu Ltd | Wholesale & retail | 2026 |
| Shining Services Limited | Administrative & support | 2024 |
| Shivjot Transport Ltd | Transport & logistics | 2025 |
| Show IT OFF Productions Ltd | Arts & recreation | 2011 |
| Shreyas Patel Ltd | Real estate | 2026 |
| Shutter Rite Limited | Manufacturing | 2010 |
| Shutters and Shop Fronts Limited | Manufacturing | 2014 |
| Shvan VIP Barber Ltd | Other services | 2023 |
| SI & PHO Ltd | Wholesale & retail | 2025 |
| Sianni Ltd | Manufacturing | 2024 |
| Siccus Ltd | Manufacturing | 2019 |
| Sidhu Estate Group Ltd | Real estate | 2025 |
| Sidhu GAS Services Ltd | Construction | 2025 |
| Sidhu Highways Ltd | Transport & logistics | 2022 |
| Sie-Drive Ltd | Transport & logistics | 2015 |
| Sienna Healthcare Solutions Ltd | Health & social care | 2023 |
| Silai Limited | Arts & recreation | 2010 |
| Silvaman Group Limited | Construction | 2015 |
| Silvaman Holdings Limited | Financial services | 2021 |
| Silvaman Property Management Limited | Real estate | 2021 |
| Silvertrees Academy Trust | Education | 2013 |
| Simply Convenience Retail Ltd | Wholesale & retail | 2024 |
| Sim’S Housing 123 Limited | Real estate | 2019 |
| Sincere Services Ltd | Administrative & support | 2022 |
| Singh Express Logistics Ltd | Transport & logistics | 2024 |
| Singing Pictures Multimedia Ltd | Extraterritorial | 2021 |
| Siran Retail Ltd | Wholesale & retail | 2023 |
| Site Solutions Limited | Information & communication | 2009 |
| SIX Paths Ltd | Information & communication | 2019 |
| Sizzle&Slice Ltd | Hospitality | 2023 |
| SJD Logistics SW Ltd | Transport & logistics | 2025 |
| SJK Motors Ltd | Wholesale & retail | 2014 |
| SJM Children's Property Company Unlimited | Administrative & support | 2014 |
| SK OFF Licensed U.K. Ltd | Wholesale & retail | 2025 |
| Skinsation by Sanaa Ltd | Other services | 2022 |
| SM Courier Ltd | Transport & logistics | 2025 |
| Smart Vehicle Tech Ltd | Wholesale & retail | 2025 |
| Smart Vent Ltd | Manufacturing | 2026 |
| Smarty Pants Private Day Nursery Limited | Education | 2007 |
| Smevkey Ltd | Wholesale & retail | 2022 |
| Smikle Solutions Limited | Wholesale & retail | 2019 |
| Smlasisi UK Limited | Wholesale & retail | 2023 |
| Smoke Hub International Ltd | Wholesale & retail | 2026 |
| SNA Investments Ltd | Arts & recreation | 2018 |
| Soccer Direct FC Ltd | Wholesale & retail | 2003 |
| Sofidale Traders Ltd | Wholesale & retail | 2020 |
| Soft Adore Ltd | Wholesale & retail | 2023 |
| Soft Driving Ltd | Transport & logistics | 2020 |
| Sohal Enterprises Limited | Transport & logistics | 2022 |
| Solar Vitamins Ltd | Manufacturing | 2024 |
| Solari Close 1963 Limited | Extraterritorial | 2014 |
| Solvyra Group Ltd | Financial services | 2026 |
| Somm Scaffolding Services Limited | Construction | 2026 |
| Sonata Transport Ltd | Transport & logistics | 2024 |
| Sonatra Ltd | Transport & logistics | 2024 |
| Soul Estates Limited | Real estate | 2016 |
| Soul Holidays Ltd | Administrative & support | 2024 |
| Source and Marketing Ltd | Wholesale & retail | 2024 |
| SP Goods Transport Ltd | Transport & logistics | 2019 |
| Space Driving School Ltd | Education | 2025 |
| Space-Box Self Storage Limited | Real estate | 2006 |
| Spare Motors Ltd | Wholesale & retail | 2025 |
| Spark N Wire Ltd | Construction | 2016 |
| SPC Bearings Limited | Extraterritorial | 1989 |
| Specialist Vehicle Logistics Limited | Administrative & support | 2005 |
| Specialist Vehicle Solutions Ltd. | Transport & logistics | 2009 |
| Spectra Fusion UK Limited | Real estate | 2025 |
| Speedy Tyres Tipton Ltd | Wholesale & retail | 2024 |
| SPH Optical Ltd | Professional & scientific | 2011 |
| Spire Vehicles Ltd | Wholesale & retail | 2025 |
| Splash Refurbishments Ltd | Construction | 2019 |
| Sporty Stars Limited | Arts & recreation | 2018 |
| Sprintertrade Ltd | Wholesale & retail | 2026 |
| SPS Shot Limited | Manufacturing | 2023 |
| Spyra-Base Hardware Limited | Manufacturing | 2004 |
| Spyra-Base Products Limited | Manufacturing | 2003 |
| SR Beauty Lounge Limited | Other services | 2021 |
| SRI Lalitha Info-Tech Limited | Professional & scientific | 2014 |
| SRI Venkateshwara Solutions Limited | Information & communication | 2025 |
| Srishiva Ltd | Administrative & support | 2025 |
| Sriss Solutions Limited | Real estate | 2021 |
| SS Bajwa Ltd | Construction | 2025 |
| SS Cargo Ltd | Transport & logistics | 2023 |
| SS Construction & Developments Ltd | Construction | 2023 |
| SS Estate Solutions Ltd | Real estate | 2024 |
| SS Global PVT Ltd | Wholesale & retail | 2019 |
| SS Properties and Assets Limited | Real estate | 2025 |
| SS Singh Construction Ltd | Construction | 2024 |
| SSB Deep Renovation Limited | Construction | 2019 |
| SSB Deep Rental Properties LLP | | 2023 |
| SSB Deep UK Rental Properties Limited | Real estate | 2024 |
| SSK Business Services Ltd | Information & communication | 2012 |
| SSSOLUTIONS1 Ltd | Transport & logistics | 2025 |
| SSW Civils & Logistics Ltd | Construction | 2018 |