| Slade Publications Ltd | Information & communication | 2025 |
| Slayfits Ltd | Wholesale & retail | 2026 |
| Slick-Movess Limited | Transport & logistics | 2016 |
| Slowhorn Farm Ltd | Agriculture & fishing | 2025 |
| SM Car Group Limited | Wholesale & retail | 2022 |
| Smart Climate Solutions Ltd | Professional & scientific | 2026 |
| Smart Ledger Accountancy and Taxation Services Ltd | Professional & scientific | 2026 |
| Smarted Consultants Ltd | Administrative & support | 2022 |
| Smartidy Cleaning Services Limited | Administrative & support | 2022 |
| Smartpropertysuk Ltd | Real estate | 2025 |
| Smartpuppys Ltd | Wholesale & retail | 2026 |
| Smarttech Autocare Limited | Wholesale & retail | 2015 |
| Smbz Ltd | Professional & scientific | 2025 |
| SME Day Ltd | Information & communication | 2024 |
| Smile Clean Ltd | Administrative & support | 2014 |
| Smith & Smith Property Ltd | Real estate | 2019 |
| Smitham Lodge Estates Limited | Real estate | 2023 |
| SMJ Lettings Limited | Real estate | 2021 |
| Smoke and Pepper Direct Ltd | Hospitality | 2025 |
| Smokey & Scopy Limited | Hospitality | 2026 |
| Snezhi-M Ltd | Administrative & support | 2019 |
| SNM Autos Ltd | Wholesale & retail | 2026 |
| Snmartuk Limited | Wholesale & retail | 2025 |
| Snowclaw Ltd | Wholesale & retail | 2025 |
| SOB Story Ltd | Professional & scientific | 2024 |
| Soccer Sponsor Superstore Ltd | Information & communication | 2025 |
| Sofia EL Harrachi Ltd | Transport & logistics | 2024 |
| Solace Entertainment Ltd | Arts & recreation | 2026 |
| Solguard Management Limited | Administrative & support | 2021 |
| Soluna Traders Ltd | Construction | 2026 |
| SOM Car Service Ltd | Wholesale & retail | 2022 |
| Sonic Build Ltd | Construction | 2020 |
| Souceonspill Ltd | Wholesale & retail | 2025 |
| South London Tyre Centre Limited | Wholesale & retail | 2007 |
| Southlondonagent Ltd | Real estate | 2025 |
| Southside Healthcare Services Limited | Wholesale & retail | 2026 |
| Southsparks Rail Consultancy Ltd | Professional & scientific | 2025 |
| Southstone Properties Ltd | Real estate | 2026 |
| SP15 Limited | Wholesale & retail | 2025 |
| Spaces Home Improvements Ltd | Construction | 2025 |
| Spicelabkitchen Ltd | Hospitality | 2026 |
| Spirit of Sugar Cakes Limited | Hospitality | 2011 |
| Sports Africa Development Company Ltd | Real estate | 2021 |
| SPV 1 Evsv Ltd | Administrative & support | 2025 |
| Square Eyes Productions Ltd | Information & communication | 2026 |
| SR Accountax Ltd | Professional & scientific | 2009 |
| SR Contruction Limited | Construction | 2025 |
| Srecnidom Limited | Wholesale & retail | 2018 |
| SRS Property Investments Ltd | Real estate | 2017 |
| Ss.B Auto Limited | Manufacturing | 2025 |
| SSA Secure Ltd | Wholesale & retail | 2021 |
| Ssbe Training & Consulting Ltd | Professional & scientific | 2019 |
| Sszg Limited | Other services | 2021 |
| ST Agnes & Partners Ltd | Real estate | 2026 |
| ST Cyprian's Greek Orthodox Primary Academy | Education | 2012 |
| ST David's Trust | Health & social care | 2010 |
| ST Fresh Food Ltd | Hospitality | 2026 |
| ST Home Renovations Ltd | Construction | 2015 |
| ST. James the Great R.C. Primary and Nursery School | Education | 2012 |
| ST7 Store Limited | Wholesale & retail | 2024 |
| Stagair Limited | | 1981 |
| Staitment Ltd | Administrative & support | 2020 |
| Stanley T Healthcare Ltd | Health & social care | 2019 |
| Star Child Nursery Ltd | Education | 2005 |
| Star Construction (London) Limited | Construction | 2023 |
| Star Home Surrey Ltd | Real estate | 2022 |
| Starlight Electricals Limited | Manufacturing | 2025 |
| Starluxe Protection Services Ltd | Administrative & support | 2025 |
| Stars Car Hire Ltd | Administrative & support | 2024 |
| State Limited | Hospitality | 2017 |
| Stavrev Building Ltd | Construction | 2018 |
| Stavrin Metodiev Ltd | Mining & quarrying | 2025 |
| Stayora Properties Ltd | Real estate | 2026 |
| Steadfast Property Management Limited | Real estate | 2025 |
| Stella DOR Christian Living Ltd | Information & communication | 2006 |
| Stellar Distributes Limited | Wholesale & retail | 2024 |
| Step Academy Trust | Education | 2011 |
| Step Consultants Limited | Health & social care | 2002 |
| Step UP Services Limited | Other services | 2016 |
| Sterling Group Properties Ltd | Real estate | 2022 |
| Sterling Tuition Ltd | Education | 2025 |
| Steve 24HR Auto Rescue Limited | Transport & logistics | 2021 |
| Stns Services Ltd | Administrative & support | 2025 |
| Stonebridge Oak Ltd | Real estate | 2025 |
| Stratosphere Ventures Limited | Wholesale & retail | 2026 |
| Streamcent Limited | Professional & scientific | 2021 |
| Street Luxe Ltd | Wholesale & retail | 2025 |
| STS Enterprisers Ltd | Wholesale & retail | 2025 |
| STUDIO1621 Limited | Construction | 2024 |
| Study in Europe Ltd | Education | 2024 |
| Stushlery Limited | Manufacturing | 2012 |
| Stylush Gents Limited | Other services | 2019 |
| Sublime Consultancy Ltd. | Wholesale & retail | 2018 |
| Suganova Limited | Manufacturing | 2026 |
| Suhana Ltd | Wholesale & retail | 2024 |
| Sukhkarta Ltd | Other services | 2026 |
| Suleymaniye Restaurant Ltd | Hospitality | 2023 |
| SUM Transport Services Ltd | Transport & logistics | 2026 |
| Summer Breeze Holdings Ltd | Real estate | 2017 |
| Summer Capsule Corp 1 Ltd | Wholesale & retail | 2025 |