| Cullco Properties Limited | Real estate | 2012 |
| CWS Inspections Limited | Transport & logistics | 2022 |
| Cyntrek Technical Ltd | Construction | 2025 |
| D & M Electrical & Media Limited | Construction | 2019 |
| D & NW Properties Ltd | Real estate | 2020 |
| D Patten Engineering Limited | Professional & scientific | 2019 |
| D Stott Consulting Ltd | Professional & scientific | 2021 |
| D.P.Stawczyk Ltd | Administrative & support | 2025 |
| Dahiya Foods Ltd | Hospitality | 2024 |
| Dalcamond Property Ltd | Real estate | 2014 |
| Darren Jackson Ltd | Health & social care | 2020 |
| Datronyx Solutions Ltd | Information & communication | 2026 |
| Davac Electrical Limited | Construction | 2009 |
| Davidson Family Limited | Households | 2022 |
| Dawsons Travel Limited | Transport & logistics | 2015 |
| DB Holdings NW Ltd | Households | 2018 |
| DBS Group Ltd | Real estate | 2025 |
| Ddcp North West Limited | Construction | 2017 |
| Decipher.Study Ltd | Information & communication | 2025 |
| Defy Limited | Professional & scientific | 2014 |
| Derby Brown Ltd | Real estate | 2020 |
| Design and Online Promotions Ltd | Information & communication | 2007 |
| Desire to Rise Ltd | Wholesale & retail | 2025 |
| Develectric Services Ltd | Construction | 2024 |
| Dewhurst Smith Law Ltd | Wholesale & retail | 2015 |
| Dhruvathara London Corporation Ltd | Administrative & support | 2023 |
| Digitav Ltd | Information & communication | 2011 |
| Dillon Invest Limited | Real estate | 2015 |
| Divi Home Essentials Ltd | Wholesale & retail | 2026 |
| DJ Services (NW) Limited | Transport & logistics | 2017 |
| DJP Digital Ltd | Information & communication | 2025 |
| DLC Direct Logistics Consulting Limited | Transport & logistics | 2017 |
| DMA Accountants Limited | Professional & scientific | 2011 |
| DMB Residential Limited | Real estate | 2015 |
| DML Couriers Ltd | Transport & logistics | 2025 |
| DNO Consultancy Services Ltd. | Real estate | 2010 |
| Dog Squad Ltd | Other services | 2024 |
| DPA Transport Services Ltd | Extraterritorial | 2024 |
| DPK Blackpool Ltd | Hospitality | 2025 |
| Drangan Accountancy & Tax Services Ltd | Professional & scientific | 2020 |
| Dripdrop Vapour Ltd | Administrative & support | 2015 |
| Drivin's Cool Ltd | Education | 2003 |
| DRY Frog Holdings Ltd | Real estate | 2026 |
| DSC Logistics Ltd | Professional & scientific | 2019 |
| Dscrutiny Technologies Limited | Information & communication | 2023 |
| Duncan Square RTM Company Limited | Households | 2026 |
| DWS Lifeskills CIC | Other services | 2017 |
| E L Automotives Ltd | Wholesale & retail | 2025 |
| E P Maintenance Ltd | Administrative & support | 2014 |
| E4-3D Engineering for Additive Manufacturing Ltd | Manufacturing | 2019 |
| EAST4WEST Indian Restaurant Ltd | Hospitality | 2024 |
| Eastwood Properties (NW) Limited | Real estate | 2025 |
| Eco Delivery Partnership Ltd | Construction | 2025 |
| Eco Evaluations Ltd | Other services | 2024 |
| Edgewing Limited | Manufacturing | 2025 |
| Edutech Group Limited | Information & communication | 2021 |
| EIM Electrical Contractors Limited | Construction | 2016 |
| EJH Properties Ltd | Real estate | 2026 |
| Eldham Grange Limited | Hospitality | 2021 |
| Electratec Limited | Manufacturing | 2023 |
| Electronics Shop Limited | Wholesale & retail | 2026 |
| Element PIC Ltd | Financial services | 2023 |
| Element Property Sourcing Ltd | Administrative & support | 2023 |
| Elevate Mortgage Solutions Ltd | Financial services | 2022 |
| Elite Holdings NW Ltd | Financial services | 2026 |
| Elite Property Developments NW Ltd | Construction | 2026 |
| Elite Scaffolding (NW) Ltd | Construction | 2014 |
| Elite Vitality Clinic Ltd | Other services | 2020 |
| Elitebuild North West Ltd | Construction | 2024 |
| Elitepawz Ltd | Agriculture & fishing | 2023 |
| Ellay Management Ltd | Arts & recreation | 2024 |
| Ellis & York Ltd. | Construction | 1992 |
| Emdr Nexus Limited | Education | 2022 |
| Emrproductions Ltd | Arts & recreation | 2023 |
| Energivault Limited | Manufacturing | 2020 |
| Energy Sprinklers UK Limited | Administrative & support | 2020 |
| Engineering Consultancy Agency Ltd | Professional & scientific | 2025 |
| Enhanced Carbons Ltd | Wholesale & retail | 2023 |
| Enigma Capital Limited | Professional & scientific | 1993 |
| Enso Build Ltd | Construction | 2021 |
| Entrust EV Technology Ltd | Manufacturing | 2021 |
| Entrust Microgrid Ltd | Professional & scientific | 2018 |
| Envirokill Ltd. | Administrative & support | 2025 |
| Environmental Project Services Limited | Professional & scientific | 1994 |
| EPE Waste Brokers Ltd | Water & waste | 2022 |
| Epicurean Cloud Ltd | Hospitality | 2025 |
| Erdast Holdings Limited | Financial services | 2021 |
| ESI Electrical Ltd | Extraterritorial | 2024 |
| Estuary Gardens Residents Association Ltd | Households | 2025 |
| Event Management and Training Ltd | Education | 2016 |
| EX Catalogue Outlet Blackpool Ltd | Wholesale & retail | 2019 |
| Exhibitor Application Systems Ltd. | Information & communication | 2016 |
| Expansion Offset Limited | Transport & logistics | 2025 |
| Fairfield Construction & Maintenance Limited | Construction | 2015 |
| Fairfield Court Management (Poulton) Limited | Households | 1983 |
| Faith Hope & Shelter Limited | Real estate | 2020 |
| Fancy Frills Ltd | Wholesale & retail | 2021 |
| Farm Escapes Limited | Hospitality | 2023 |
| Fast Leisure Ltd | Hospitality | 2026 |
| FCR Electrical Ltd | Professional & scientific | 2023 |