| Radlink Limited | | 1989 |
| Ramsden Capital London Limited | Real estate | 2022 |
| Range Consultants Limited | Real estate | 1985 |
| Rarenest Ltd | Wholesale & retail | 2025 |
| Raven Music Limited | Information & communication | 2017 |
| RCW Strategic Consulting Ltd | Professional & scientific | 2025 |
| RD Cosmedics Ltd | Health & social care | 2016 |
| Reamcare Limited | Health & social care | 1999 |
| Reasonable and Informed Third Party Limited | Professional & scientific | 2021 |
| Rebecca Walker Ltd | Professional & scientific | 2018 |
| Red FOX Luxury Lifestyle Limited | Administrative & support | 2016 |
| Red TX Audio Limited | Information & communication | 2021 |
| Redlands Electrical Ltd | Manufacturing | 2013 |
| Redroofs Estates Limited | Real estate | 2011 |
| Redroofs Holdings Limited | Financial services | 2018 |
| Refresh Air Conditioning Ltd | Manufacturing | 2021 |
| Regalgate Properties Limited | Real estate | 2006 |
| Regent Services Limited | Professional & scientific | 1982 |
| Reiki Healing Angels Limited | Health & social care | 2024 |
| Renewa Formula Ltd | Wholesale & retail | 2024 |
| Reset: the Britain Project Limited | Professional & scientific | 2020 |
| Residency Rooms Limited | Real estate | 2026 |
| Responsiblerisk Ltd | Professional & scientific | 2019 |
| Rheumetec Limited | Health & social care | 2016 |
| Riemans Limited | Wholesale & retail | 2006 |
| Rise LA Ltd | Administrative & support | 2024 |
| River Avenue Partnership LLP | | 2021 |
| Rlmja Consulting Limited | Professional & scientific | 2009 |
| Rlta Limited | Information & communication | 2014 |
| Rmartensr Limited | Other services | 2026 |
| Rock Star Sushi Bar Limited | Hospitality | 2021 |
| Rogue Otter Studios Ltd | Information & communication | 2023 |
| Romilly.Com Ltd | Information & communication | 2006 |
| Rooted Productions Ltd | Information & communication | 2024 |
| Rosart Holdings Limited | Professional & scientific | 2019 |
| Rosendal Ltd | Real estate | 2026 |
| Rosie and Hugh Ltd | Arts & recreation | 2023 |
| Rosmaninho Properties Limited | Real estate | 2017 |
| Rowan Projects Limited | Other services | 2025 |
| RQL Consulting Ltd | Professional & scientific | 2018 |
| RS Business Modelling Limited | Professional & scientific | 2009 |
| Rubydream Property Co. Limited | Construction | 1992 |
| Ruddy Electrical Limited | Construction | 2015 |
| Rueckenwind Ltd | Professional & scientific | 2019 |
| Runway Coaching Limited | Professional & scientific | 2022 |
| Russell Analytics & Consulting Limited | Professional & scientific | 2017 |
| Rythe Bank Close Limited | Households | 2011 |
| S&W Pubs London Ltd | Hospitality | 2024 |
| SA London Prime Ltd | Real estate | 2025 |
| Sable Interiors Limited | Wholesale & retail | 2006 |
| Sabre Developments Ltd | Construction | 2022 |
| Safe Pair of Hands Technology Limited | Professional & scientific | 2017 |
| Saffa Scapes Ltd | Other services | 2016 |
| SAI Leela Sarp Limited | Real estate | 2025 |
| Salivie Ltd | Professional & scientific | 2025 |
| SAM & Co Constructions Ltd | Real estate | 2020 |
| Samia Aesthetics Limited | Other services | 2022 |
| Sand Strand Limited | Information & communication | 2014 |
| Sandcons Ltd | Administrative & support | 2008 |
| Santini LLP | | 2012 |
| Sarah Brooke Consulting Limited | Professional & scientific | 2018 |
| Sari Enterprises Ltd | Wholesale & retail | 2015 |
| Saskia Kate Interiors Ltd | Professional & scientific | 2021 |
| Saturne Limited | Wholesale & retail | 2019 |
| SBI EDU Courses Ltd | Information & communication | 2026 |
| SBT Consultants Limited | Wholesale & retail | 2007 |
| Scarlet-T Screen Ltd | Arts & recreation | 2001 |
| Sdjc Consulting Limited | Information & communication | 2025 |
| SDR Advisors Ltd | Professional & scientific | 2019 |
| Seraphina 22 Limited | Information & communication | 2020 |
| Serious Solar Limited | Construction | 2021 |
| Server Support R US Limited | Information & communication | 2026 |
| Sexton's Bar Ltd | Hospitality | 2020 |
| Seymour Grange (Thames Ditton) Management Company Limited | Households | 2021 |
| Sgclarity Ltd | Professional & scientific | 2025 |
| Shaheen Zaman Khan Law Limited | Professional & scientific | 2023 |
| Sharp Workshop Services (SWS) Limited | Construction | 2014 |
| Sheldon House Securities Limited | Real estate | 1967 |
| Shiroboard Ltd | Education | 2025 |
| SHL Debtco Limited | Financial services | 2018 |
| SHL Global Holdings 1 Limited | Financial services | 2018 |
| SHL Global Holdings 2 Limited | Financial services | 2018 |
| SHL Global Holdings Midco II Limited | Financial services | 2023 |
| SHL Global Holdings Midco Limited | Financial services | 2019 |
| SHL Global Management Limited | Financial services | 2018 |
| SHL India Finance Limited | Financial services | 2019 |
| SHL International Finance 1 Limited | Financial services | 2018 |
| SHL International Finance 2 Limited | Financial services | 2018 |
| SHL International Management Limited | Financial services | 2018 |
| SHL Product Ltd | Financial services | 2008 |
| SHL US Finance Limited | Financial services | 2018 |
| Shofar Films Limited | Information & communication | 2010 |
| Shop of Requirement UK Limited | Wholesale & retail | 2017 |
| Singularity Health Ltd | Information & communication | 2025 |
| Singularity Holdings Limited | Financial services | 2019 |
| Singularity Venture Advisers Limited | Professional & scientific | 2018 |
| SIP & Thrift Limited | Wholesale & retail | 2026 |
| Sjrk Consulting Limited | Professional & scientific | 2013 |
| Skin Insight Ltd | Professional & scientific | 2016 |
| Sleon Architecture Ltd | Professional & scientific | 2016 |