| Thame Football Partnership (Thame United FC and Thame Boys, Youth and Girls FC) Limited | Arts & recreation | 2010 |
| Thame Hub Ltd | Professional & scientific | 2016 |
| Thame Jewellery Workshop Limited | Wholesale & retail | 2014 |
| Thame Partnership Academy Trust | Education | 2012 |
| Thame Players Theatre Company | Arts & recreation | 2002 |
| Thame Scissors Ltd | Other services | 2025 |
| Thame Service Station Limited | Wholesale & retail | 1994 |
| Thame Snooker Club Ltd | Arts & recreation | 1994 |
| Thame Sports Club Limited | Arts & recreation | 2017 |
| Thame Tooling Solutions Limited | Wholesale & retail | 2022 |
| Thame Town Cricket Club Limited | Arts & recreation | 2017 |
| Thame Trotters Ltd | Real estate | 2017 |
| Thames Nails Ltd | Other services | 2026 |
| Thames Pizzeria Ltd | Hospitality | 2025 |
| Thames Steamers Limited | Transport & logistics | 1999 |
| Thameside Financial Planning Limited | Professional & scientific | 2013 |
| Thamesmead Limited | Wholesale & retail | 2014 |
| Thatgood Limited | Information & communication | 2004 |
| THE Active Toy Company Limited | Arts & recreation | 2001 |
| THE Agency of Design Ltd | Professional & scientific | 2011 |
| THE Avenue Solutions Ltd | Professional & scientific | 2020 |
| THE Brand Inside Limited | Professional & scientific | 2001 |
| THE Coaching & Mentoring Network Ltd. | Professional & scientific | 1999 |
| THE College of Animal Physiotherapy Limited | Professional & scientific | 2007 |
| THE Communication Quarter Ltd | Education | 2024 |
| THE Conversation Project Ltd | Professional & scientific | 2019 |
| THE Cottage Bakery Thame Ltd | Manufacturing | 2012 |
| THE Door Replacement Company Limited | Construction | 2012 |
| THE Enchanted Group Ltd | Administrative & support | 2011 |
| THE Fighter (Bristol) Ltd | Arts & recreation | 2009 |
| THE Filthy Moustache UK Ltd | Hospitality | 2024 |
| THE Finishing Studio Limited | Manufacturing | 2018 |
| THE Foundation Learning Company Limited | Education | 2019 |
| THE Frank Impact Company Ltd | Professional & scientific | 2021 |
| THE Geoffrey Harrison Foundation | Education | 2011 |
| THE Global Fund for Forgotten People, Order of Malta | Health & social care | 2012 |
| THE Gurr Ltd | Other services | 2018 |
| THE HR Agency Limited | Administrative & support | 2020 |
| THE Jack O'Donnell Foundation Ltd | Arts & recreation | 2010 |
| THE Joey Beauchamp Foundation | Education | 2023 |
| THE Line Animation Studio Ltd | Information & communication | 2017 |
| THE Metalworks Film & TV Ltd | Manufacturing | 2024 |
| THE Move Clinic Ltd | Health & social care | 2024 |
| THE Nutrition Advantage Ltd | Health & social care | 2023 |
| THE Old Grain Store (Thame) Management Company Limited | Real estate | 2016 |
| THE Old Printworks Thame Ltd | Administrative & support | 2008 |
| THE Old School House Care Home (South West) Ltd | Health & social care | 2010 |
| THE Old School House Care Home LLP | | 2011 |
| THE Pickleball Company Ltd | Extraterritorial | 2019 |
| THE Picnic Hamper Limited | Hospitality | 2010 |
| THE Practice - Thame Ltd | Health & social care | 2018 |
| THE Practice - Thame Property Management Ltd | Real estate | 2025 |
| THE Recruitment Strategist Limited | Administrative & support | 2021 |
| THE Red Bottle Company Limited | Wholesale & retail | 2013 |
| THE Retail Audit Company Limited | Information & communication | 1996 |
| THE Rolling Heat Company Ltd | Wholesale & retail | 2026 |
| THE Room at Berryfields Ltd | Other services | 2022 |
| THE Rycote Estate Limited | Real estate | 2000 |
| THE Stage Scenery Co Limited | Manufacturing | 2006 |
| THE Star and Garter (Thame) Ltd | Hospitality | 2018 |
| THE Sydenham PUB Company Limited | Real estate | 2008 |
| THE Thame and Oxfordshire County Agricultural Association | Other services | 2000 |
| THE Treehouse Thame Limited | Education | 2015 |
| THE Vantage Clinic Ltd | Education | 2022 |
| THE Visual People Ltd | Professional & scientific | 2017 |
| THE Weedon Project Ltd | Hospitality | 2024 |
| THE Wildwood Organisation Limited | Professional & scientific | 2014 |
| THE Woodman Pinner Limited | Hospitality | 2021 |
| THE Woodworks Trading Limited | Hospitality | 2017 |
| THE Workers (International) Ltd | Professional & scientific | 2018 |
| THE YARD@OX9 Ltd | Real estate | 2020 |
| Thee Box Ltd | Professional & scientific | 2020 |
| Thehill Innovation Limited | Extraterritorial | 2022 |
| Therapy Services Management Limited | Health & social care | 2016 |
| Therme Hydroponics Farm Solutions Limited | Agriculture & fishing | 2021 |
| Therme RPC Limited | Manufacturing | 2020 |
| Thistley Ltd | Professional & scientific | 2026 |
| THK Property Limited | Real estate | 2025 |
| Thorium Consult Ltd | Professional & scientific | 2025 |
| Thousand Studios Limited | Information & communication | 2024 |
| Three Pigeons Investments Limited | Real estate | 2021 |
| Three Rocks Ltd | Information & communication | 2001 |
| Thrive Alcohol Free Ltd | Education | 2023 |
| Throop Properties Limited | Real estate | 2008 |
| Thtdfm Limited | Financial services | 2008 |
| Tibo Audio Limited | Wholesale & retail | 2015 |
| Ticol Limited | Professional & scientific | 2013 |
| Tiddington Leisure Ltd | Hospitality | 2019 |
| Tiddington Village Hall Trading Limited | Hospitality | 2025 |
| Tier One Agency Limited | Arts & recreation | 2022 |
| Tife Holdings Limited | Financial services | 2018 |
| Tigernet Solutions Limited | Information & communication | 1996 |
| Tigon (G.B.) Limited | Health & social care | 1996 |
| TIM Brooks Consultants Limited | Professional & scientific | 2014 |
| Timothy Howard Homes Ltd | Construction | 2024 |
| TIN & LEW Trading Ltd | Wholesale & retail | 2023 |
| Tina Fegent Limited | Professional & scientific | 2008 |
| Tio's Bar & Events Ltd | Wholesale & retail | 2023 |
| Tipscapital Ltd | Real estate | 2025 |
| Tipstrade Limited | Other services | 2003 |