| LEARNINGE7 Ltd | Professional & scientific | 2025 |
| Leasestuff Ltd | Administrative & support | 2012 |
| Ledborough Developments Limited | Real estate | 1966 |
| LEE & Lindars (Oxford) Limited | Real estate | 1996 |
| LEE Burbury Construction Limited | Construction | 2015 |
| Lees White Limited | Professional & scientific | 2008 |
| Legal-Eye Ltd | Professional & scientific | 2009 |
| Legit Systems Limited | Information & communication | 2003 |
| Lemon Pebble Ltd | Administrative & support | 2020 |
| Lemongrass Marketing Limited | Professional & scientific | 2008 |
| Lemonjelly Childcare Solutions Ltd | Administrative & support | 2015 |
| Let's Build I.T. Solutions Ltd | Information & communication | 2019 |
| Let's DO IT Production Company Limited | Arts & recreation | 1983 |
| Lever Investments Limited | Administrative & support | 2003 |
| Lewis Motors (Oxford) Ltd | Wholesale & retail | 2018 |
| LFH & Co Mortgage Solutions Ltd | Financial services | 2024 |
| Liberty Steel Structures Limited | Extraterritorial | 2021 |
| Life Surfer Ltd | Information & communication | 2022 |
| Lightfoots LLP | | 2009 |
| Lightfoots Solicitors Limited | Professional & scientific | 2020 |
| Lighthouse (UK) Holdco Limited | Professional & scientific | 2012 |
| Lighthouse (UK) Limited | Manufacturing | 2002 |
| Lightwater Consulting Limited | Information & communication | 1992 |
| Lightway Services (Oxfordshire) Ltd | Transport & logistics | 2024 |
| Lightway Services Ltd | Transport & logistics | 2018 |
| Lightway Solutions (Oxon) Ltd | Transport & logistics | 2021 |
| LIL Nashville (Bristol) Ltd | Hospitality | 2026 |
| LIL Nashville (Chiswick) Ltd | Hospitality | 2024 |
| Linear Machine Tools Limited | Wholesale & retail | 2014 |
| Lineham Services Ltd | Other services | 2014 |
| Little Ankle Biters Ltd | Information & communication | 2018 |
| Little Masters Limited | Education | 2026 |
| Littlock Limited | Professional & scientific | 2003 |
| Live and Direct Events Ltd | Administrative & support | 2020 |
| Livesey Building Consultancy Ltd | Professional & scientific | 2020 |
| Livvy Nicole Ltd | Other services | 2014 |
| Ljwb Consulting Limited | Professional & scientific | 2018 |
| Llangollen Wharf Limited | Professional & scientific | 2019 |
| LM Quin Construction Ltd | Construction | 2022 |
| LMA Softplay Hire Ltd | Arts & recreation | 2026 |
| LNC Rentals Ltd | Real estate | 2022 |
| Loaded Event Catering Ltd | Hospitality | 2025 |
| Local Medical Services Limited | Health & social care | 2012 |
| Loco Bingo Ltd | Administrative & support | 2017 |
| Locutions Limited | Information & communication | 2017 |
| Loddon Consulting LLP | | 2024 |
| Lola Media Ltd | Information & communication | 2009 |
| Longacre Vita Ltd | Construction | 2024 |
| Longwall Venture Partners LLP | | 2011 |
| Longwall Ventures 3 ECF (FP) LLP | | 2017 |
| Longwall Ventures 3 ECF (GP) LLP | | 2017 |
| Longwall Ventures 3 ECF (GP) Member Limited | Financial services | 2017 |
| Longwall Ventures 3 ECF (Nominee) Limited | Financial services | 2017 |
| Longwall Ventures 3 ECF LP | | 2017 |
| Longwall Ventures 4 ECF LP | | 2026 |
| Longwall Ventures ECF (FP) LLP | | 2012 |
| Longwall Ventures ECF (GP) LLP | | 2012 |
| Longwall Ventures ECF (GP) Member Limited | Financial services | 2012 |
| Longwall Ventures ECF LP | | 2012 |
| Longwick Mill Residents Company 2009 Limited | Households | 2010 |
| Look 4 Tyres Limited | Wholesale & retail | 2003 |
| Loom Consulting Ltd | Professional & scientific | 2025 |
| Looom Ltd | Administrative & support | 2026 |
| Lopemede Nature Connection CIC | Education | 2025 |
| Louise Holt Design Limited | Professional & scientific | 2016 |
| Love Branding Limited | Wholesale & retail | 2021 |
| Lovelace Search Limited | Administrative & support | 2021 |
| Lower END Paddock Limited | Agriculture & fishing | 2020 |
| Loweswater Investments | Financial services | 2024 |
| Loyal Landlords Ltd | Real estate | 2017 |
| Lucky 13 Investments Limited | Administrative & support | 2025 |
| Luffy AI Limited | Information & communication | 2018 |
| Luminorum Limited | Manufacturing | 2005 |
| Luxe Bespoke Ltd | Construction | 2026 |
| Luxe Minds Advisory Ltd | Professional & scientific | 2025 |
| Lymphshop Limited | Extraterritorial | 2020 |
| Lynam Pharma Limited | Health & social care | 2013 |
| M & K Hair Design Limited | Other services | 2024 |
| M & L Hedges Ltd | Real estate | 2025 |
| M Collins Finance Limited | Financial services | 2017 |
| M L Hobbs (Oxford) Limited | Construction | 2006 |
| M W Security Solutions Limited | Administrative & support | 2008 |
| M&Lo Ltd | Professional & scientific | 2017 |
| M-Flow Meters Limited | Extraterritorial | 2012 |
| M-Flow Technologies Limited | Professional & scientific | 2011 |
| M.P. Printers (Thame) Limited | Manufacturing | 1975 |
| M40CARS Oxfordshire Limited | Transport & logistics | 2021 |
| MAC Tech Consulting Ltd | Information & communication | 2024 |
| Macdonald Broadcast Services Limited | Extraterritorial | 1999 |
| Macrow Group Holdings Ltd | Financial services | 2023 |
| Magerik Limited | Administrative & support | 1982 |
| Maison August Limited | Information & communication | 2015 |
| Maison Luméra Ltd | Other services | 2026 |
| Maisongb Ltd | Professional & scientific | 2024 |
| Major Farm Services Limited | Agriculture & fishing | 2014 |
| Make OUR Book Limited | Education | 2017 |
| Makertorium Ltd | Professional & scientific | 2011 |
| Malaika Energy Ventures Ltd | Professional & scientific | 2015 |
| Malaika Health Ltd | Financial services | 2025 |
| Malaika International Limited | Financial services | 2025 |