| Ultraconnect Perimeter Access Surveillance Limited | Manufacturing | 2019 |
| Ultrapure Health Group Ltd | Wholesale & retail | 2025 |
| Uluus Capital Limited | Professional & scientific | 2018 |
| UMA Telford Muaythai Ltd | Education | 2024 |
| Umboti Ltd | Other services | 2020 |
| Undefinable Company Ltd | Administrative & support | 2021 |
| Underwood Pipelines Limited | Construction | 2009 |
| Unique Cleans (Shropshire) Ltd | Administrative & support | 2025 |
| Unique Home Support Ltd | Health & social care | 2025 |
| Unique Nights Ltd | Real estate | 2024 |
| Unison Property Enterprise Limited | Real estate | 2016 |
| United Communities Network C.I.C. | Education | 2024 |
| United Networks System Ltd | Manufacturing | 2021 |
| United Pro Limited | Information & communication | 2014 |
| Unitnumber Property Management Limited | Households | 1993 |
| Unitom Ltd | Other services | 2020 |
| Unity 4 Contact Centre Technology Ltd | Information & communication | 2011 |
| Unity Care Shropshire Ltd | Health & social care | 2026 |
| Unity Health Partnership Ltd | Health & social care | 2026 |
| UNITY4 UK Limited | Administrative & support | 2010 |
| Universal Art Ltd | Wholesale & retail | 2026 |
| Universal Transport Ltd | Transport & logistics | 2011 |
| Upgrade Tuition Ltd | Education | 2020 |
| Uppal Corporation Ltd | Health & social care | 2023 |
| Uppal Euro Transport Ltd | Transport & logistics | 2007 |
| Upper Hattons Ltd | Agriculture & fishing | 2026 |
| Upright Scaffold Limited | Construction | 2010 |
| Upscale Cleaning Ltd | Administrative & support | 2025 |
| Uptons Electrical & Security Ltd | Construction | 2025 |
| Uptons Removals Limited | Transport & logistics | 2002 |
| Urban Automotive Services Ltd | Extraterritorial | 2025 |
| Urban Control Limited | Extraterritorial | 2016 |
| Urban Fortress Limited | Wholesale & retail | 2019 |
| Urban Valley Properties Limited | Real estate | 2017 |
| Urey & Helliwell Homes Ltd | Real estate | 2026 |
| Usben Contracting Ltd | Administrative & support | 2018 |
| Userve Internet Limited | Information & communication | 2003 |
| Uskatt Ltd | Other services | 2019 |
| Utilise Consultancy Services Ltd | Energy | 2026 |
| Utility Advice Company Limited | Other services | 2019 |
| UTU Properties Ltd | Real estate | 2025 |
| UX Media Group Ltd | Other services | 2023 |
| UYP Coaching Ltd | Professional & scientific | 2023 |
| V & D Freight Ltd | Transport & logistics | 2026 |
| V a Technology Limited | Manufacturing | 1988 |
| V&D Exteriors Ltd | Construction | 2022 |
| V&D Interiors Ltd | Construction | 2012 |
| V'Oteak Ltd | Wholesale & retail | 2024 |
| V. Marsh & SON Limited | Real estate | 1955 |
| V.A.J Limited | Wholesale & retail | 2006 |
| V2NET Ltd | Information & communication | 2023 |
| Vadukul Investments Limited | Households | 2013 |
| VAL & LYN Jones Ltd | Wholesale & retail | 2021 |
| Vale Retail Ltd | Wholesale & retail | 2019 |
| Valgath Ventures Ltd | Real estate | 2025 |
| Valkyr Vesta CIC | Other services | 2026 |
| Valo Light Ltd | Manufacturing | 2016 |
| Valour Investments Ltd | Financial services | 2025 |
| Valour Security Ltd | Information & communication | 2014 |
| Value Celebrations Limited | Wholesale & retail | 2024 |
| Valuedrive Ltd | Information & communication | 2026 |
| Valuesoft Limited | Information & communication | 2006 |
| Valy Transport Ltd | Transport & logistics | 2015 |
| Vamptree Limited | | 1981 |
| Van Beek Limited | Wholesale & retail | 2024 |
| Van Window Installations Limited | Wholesale & retail | 2021 |
| VAN4YOU Logistics Ltd | Transport & logistics | 2025 |
| Vanascarservice Ltd | Manufacturing | 2024 |
| Vanes Advisory Ltd | Financial services | 2025 |
| Vangaurd Ltd | Transport & logistics | 2006 |
| Vangelix Limited | Real estate | 2025 |
| Vanguard Alarms Ltd | Administrative & support | 1978 |
| Vanguard Talent Ltd | Administrative & support | 2025 |
| Vani Logistics Ltd | Transport & logistics | 2024 |
| Vanjeks Management Ltd | Professional & scientific | 2011 |
| Vanland.Co.Uk Limited | Wholesale & retail | 2005 |
| Vanman Transport Limited | Transport & logistics | 2021 |
| Vanta Freight Ltd | Transport & logistics | 2022 |
| Vantage Sport Limited | Wholesale & retail | 2016 |
| Vantage VC Limited | Administrative & support | 2004 |
| Vantage Vehicle Accessories Limited | Wholesale & retail | 2016 |
| Vantage Vehicle Livery Limited | Wholesale & retail | 2016 |
| Vantage Vehicle Signs Limited | Wholesale & retail | 2016 |
| Vape N Quit Limited | Wholesale & retail | 2014 |
| Vape Stop 1 Ltd | Wholesale & retail | 2026 |
| Varalakshmi Ltd | Wholesale & retail | 2024 |
| Vartau Trans Ltd | Transport & logistics | 2020 |
| Vatec Limited | Manufacturing | 2008 |
| Vatta Limited | Financial services | 2021 |
| Vatwise Business Services Limited | Professional & scientific | 2013 |
| Vaulted Vortex Ltd | Wholesale & retail | 2025 |
| Vaztik Ltd | Wholesale & retail | 2019 |
| VB Architecture Ltd | Professional & scientific | 2021 |
| VBF Limited | Extraterritorial | 2010 |
| Vccpanda Limited | Wholesale & retail | 2022 |
| VDV Fibre Ltd | Construction | 2022 |
| Veanti Ltd | Professional & scientific | 2008 |
| Veenow Limited | Manufacturing | 2023 |
| Veeru Limited | Information & communication | 2026 |
| Veetireco UK Limited | Wholesale & retail | 2014 |