| EON Books Limited | Wholesale & retail | 2014 |
| EP Logs Ltd | Agriculture & fishing | 2024 |
| Epic Park Escapes Ltd | Administrative & support | 2025 |
| EPO Groundworks Ltd | Construction | 2023 |
| Epos Commerce Solutions Limited | Wholesale & retail | 2013 |
| Equilibre Holistic Therapy Ltd | Other services | 2015 |
| ER Financial Limited | Financial services | 2024 |
| Eraya Limited | Professional & scientific | 2024 |
| Ercall Cleaning Limited | Administrative & support | 2021 |
| Ercall Developments Limited | Real estate | 2004 |
| Ercall Maintenance Services Ltd | Information & communication | 2020 |
| Erebus Solutions Ltd | Manufacturing | 2019 |
| Eric Contracting Ltd | Transport & logistics | 2022 |
| Erik Wood Production Limited | Administrative & support | 2006 |
| Erip General Partner Limited | Administrative & support | 2007 |
| Ernest Graham Associates Ltd. | Health & social care | 2019 |
| Ernwell Finance Limited | Professional & scientific | 2025 |
| ERP O Limited | Professional & scientific | 2023 |
| Erraji Development Finance Ltd | Professional & scientific | 2017 |
| Erraji Financial Solutions Limited | Financial services | 2016 |
| Erraji Holdings Ltd | Professional & scientific | 2023 |
| Erraji Investments Ltd | Construction | 2017 |
| Erraji Property Management Ltd | Households | 2026 |
| Erun Limited | Wholesale & retail | 2019 |
| Erwit Ltd | Other services | 2019 |
| Escape Assessment Ltd | Education | 2022 |
| Eseveo Ltd | Other services | 2020 |
| ESG Estate Limited | Real estate | 2025 |
| ESK Terrace Development Limited | Real estate | 2022 |
| Essence (Telford) Ltd. | Health & social care | 2014 |
| Essence Healthcare Limited | Administrative & support | 2026 |
| Essential Car Parts Ltd | Wholesale & retail | 2017 |
| Essential Choice Ltd. | Wholesale & retail | 2016 |
| Essential Ice Ltd | Manufacturing | 2022 |
| Essentially Online Ltd | Wholesale & retail | 2020 |
| Essington Information Technology Services Ltd | Information & communication | 2009 |
| EST Holdings & Investments Ltd | Financial services | 2024 |
| Estat Solutions Limited | Wholesale & retail | 2013 |
| Esthel Company Limited | Health & social care | 2023 |
| Etacsolutions Limited | Information & communication | 2006 |
| Etak Creative Ltd | Professional & scientific | 2016 |
| Etaxation Ltd | Extraterritorial | 2021 |
| Eternia Property Limited | Real estate | 2015 |
| Eternity Developments Limited | Real estate | 2006 |
| Eternity Estates Limited | Construction | 2006 |
| Eternity Homes Limited | Construction | 2006 |
| Eterquest Ltd | Other services | 2020 |
| Ethical Compliance Ltd | Extraterritorial | 2024 |
| Eunevious Ltd | Health & social care | 2020 |
| Euro Access (Walsall) Limited | Manufacturing | 2003 |
| Euro Escapes Ltd | Administrative & support | 2026 |
| Eurokey Holdings Limited | Water & waste | 2019 |
| Eurokey Recycling Limited | Water & waste | 1995 |
| Euronix Ltd | Construction | 2024 |
| Europa Energy Ltd | Administrative & support | 2012 |
| Europe Invest Ltd | Construction | 2019 |
| European Halal Tours Ltd | Administrative & support | 2016 |
| European Innovation Limited | Information & communication | 2001 |
| Eurosid Ltd | Other services | 2019 |
| Eurotherm Holdings Limited | Professional & scientific | 1975 |
| Eurotherm International Investments Limited | Professional & scientific | 1982 |
| Eurotronix Ltd | Manufacturing | 2012 |
| EV Charge Points UK T/A Evcp Ltd | Extraterritorial | 2020 |
| Evadis Limited | Professional & scientific | 1998 |
| Evall Management Limited | Professional & scientific | 2010 |
| Evans Auto Care Telford Ltd | Wholesale & retail | 2025 |
| Evans Environmental Services Ltd | Water & waste | 2016 |
| Evason Building Contractors Ltd | Construction | 2025 |
| EVE Consulting Ltd | Professional & scientific | 2025 |
| Event Gear Limited | Hospitality | 2026 |
| Event Vault Ltd | Administrative & support | 2025 |
| Ever Rising Group Ltd | Transport & logistics | 2026 |
| Everest Property Solution Ltd | Households | 2022 |
| Everfresh Foods Limited | Hospitality | 2018 |
| Everfresh Group Limited | Real estate | 2025 |
| Evergreen Occupational Therapy Services Limited | Health & social care | 2017 |
| Everills Limited | Arts & recreation | 2025 |
| Everready Health and Social Care Solutions Ltd | Health & social care | 2019 |
| Every Life IS Precious (Elip) Ltd | Health & social care | 2026 |
| Everyday Property Ltd | Real estate | 2024 |
| Everything Services Commercial Cleaning Limited | Administrative & support | 2025 |
| Evidan Limited | Real estate | 2021 |
| Evil Culture Limited | Professional & scientific | 2020 |
| Evil Holdings Limited | Financial services | 2022 |
| EVN Store Ltd | Wholesale & retail | 2024 |
| Evoak Carpentry and Joinery Limited | Construction | 2016 |
| Evocore Ltd | Wholesale & retail | 2025 |
| Evolution Foods Ltd | Manufacturing | 2006 |
| Evolution Home and Leisure Limited | Manufacturing | 2021 |
| Evolution Shrewsbury Investments Limited | Financial services | 2021 |
| Evolution Technologies Ltd | Manufacturing | 2018 |
| Evopack Limited | Administrative & support | 2010 |
| Evoreach Ltd | Professional & scientific | 2024 |
| Ewms Telford Ltd | Extraterritorial | 2015 |
| Ewutan Ltd | Other services | 2019 |
| Ex-Forces to Community's CIC | Arts & recreation | 2024 |
| Exact Systems Limited | Professional & scientific | 2013 |
| Exascale (Telford) Limited | Information & communication | 2026 |
| Exascale Limited | Information & communication | 2010 |
| Excelement Technology Ltd. | Manufacturing | 2010 |