| E.Y.E. Sport & Design (UK) Limited | Extraterritorial | 2021 |
| EAC Telford Commercial Ltd | Wholesale & retail | 2023 |
| EAC Telford Limited | Wholesale & retail | 2013 |
| Eagle Court (2007) Limited | Households | 2006 |
| Eagle Engineering Ltd | Manufacturing | 2002 |
| Eagle Estate Developments Ltd | Construction | 2025 |
| Eagle Hurst Group Ltd | Health & social care | 2020 |
| Eagle Mews Ltd | Construction | 2017 |
| Eaglestone Executive Ltd. | Professional & scientific | 2020 |
| Eaglewings Property Limited | Real estate | 2025 |
| Eala Wellington Limited | Hospitality | 2025 |
| EAR Health Clinic DR Sturges & RCN Inston Limited | Health & social care | 2024 |
| Early Milestones Ltd | Education | 2020 |
| Earlyraiser Care Ltd | Health & social care | 2026 |
| Earsfort Ltd | Other services | 2020 |
| Earth Constructions Ltd | Construction | 2025 |
| Earth Glow Cleaning Co Ltd | Administrative & support | 2023 |
| Earthly Angels Ltd. | Health & social care | 2023 |
| Easigift Limited | Information & communication | 2024 |
| East View Builders Limited | Construction | 2014 |
| Eastwick Consulting Limited | Information & communication | 2007 |
| Easy Admin Payroll Hotels Ltd | Hospitality | 2025 |
| Easy's Shop Ltd | Other services | 2023 |
| Easycare (UK) Limited | | 1983 |
| Easylease Vehicles Limited | Administrative & support | 2017 |
| Easypay Express Ltd | Administrative & support | 2025 |
| Easyrise Holdings Limited | Financial services | 2015 |
| Easyrise Limited | Manufacturing | 2013 |
| Easyrise Management Limited | Professional & scientific | 2017 |
| EAT Well Supplies Ltd | Wholesale & retail | 2025 |
| EB Housing Ltd | Real estate | 2022 |
| Eben-Ezer Inc Ltd | Transport & logistics | 2021 |
| Ebojon Limited | Wholesale & retail | 2024 |
| Ecaa Trade Consultancy Ltd | Wholesale & retail | 2025 |
| ECF Supply Limited | Wholesale & retail | 2026 |
| Echolux Ltd | Administrative & support | 2026 |
| Eco Electrical Contractors LLP | | 2008 |
| Eco Living Shropshire Limited | Wholesale & retail | 2026 |
| Eco Plumbing & Electrical Solutions Ltd | Extraterritorial | 2014 |
| Eco Solutions Recycling Ltd | Households | 2024 |
| Ecofficiency Limited | Water & waste | 2009 |
| Ecofusionelectrics Ltd | Construction | 2025 |
| Ecolus Ltd | Other services | 2020 |
| Ecoluxe Decor Ltd | Arts & recreation | 2024 |
| Ecomm Trading Limited | Wholesale & retail | 2020 |
| Ecoply UK Limited | Construction | 2014 |
| Ecovate Partnership Limited | Professional & scientific | 2016 |
| Ecovend Ltd | Water & waste | 2008 |
| Edan Gifts Ltd | Manufacturing | 2025 |
| Edan Group Ltd | Financial services | 2025 |
| EDC Holdings Limited | Professional & scientific | 2006 |
| Eden Housing & Support Ltd | Real estate | 2019 |
| Eden Shutters & Blinds Limited | Administrative & support | 2019 |
| Edenica Ltd | Other services | 2023 |
| Eder Tower Services Limited | Hospitality | 2019 |
| Edesiri Limited | Wholesale & retail | 2022 |
| Edgbrookton Ltd | Wholesale & retail | 2014 |
| Edge Accounting Ltd | Professional & scientific | 2023 |
| Edge Sculpture Limited | Wholesale & retail | 2006 |
| Edgmond Foods Limited | Manufacturing | 1990 |
| Edit Digital Solutions Ltd | Information & communication | 2018 |
| Edit Renovations Limited | Construction | 2025 |
| Edlyne Associates Limited | Information & communication | 2011 |
| Edna Maud Care Services Ltd | Health & social care | 2025 |
| EDU-FIT4SCHOOLS Ltd | Education | 2011 |
| Eduard Logistic Ltd | Transport & logistics | 2022 |
| EDUFIT4TRAINING Ltd | Education | 2019 |
| Edward Barclay Developments Limited | Real estate | 2009 |
| Edward Foster Properties Limited | Real estate | 2013 |
| Edwards Property Services Limited | Real estate | 2025 |
| Edwardsflint Properties Limited | Extraterritorial | 2024 |
| Edward’S Glass Replacement Ltd | Construction | 2025 |
| EE Drylining Limited | Professional & scientific | 2020 |
| EEE and CEE Medicals Limited | Health & social care | 2024 |
| Efaflex UK Limited | Wholesale & retail | 2002 |
| Effortless Skin & Laser Clinic Ltd | Other services | 2022 |
| Efitam Ltd | Other services | 2019 |
| Egendom Investments Limited | Real estate | 2021 |
| EGL Catering Equipment Ltd | Wholesale & retail | 2021 |
| Egon Limited | Other services | 2003 |
| Egon Vehicle Leasing Limited | Professional & scientific | 2014 |
| EGS Properties Midland Ltd | Real estate | 2026 |
| EGV Property Holdings Limited | Real estate | 2014 |
| EH Advisory Limited | Other services | 2017 |
| EIE Services Ltd | Education | 2026 |
| Eigenvector Solutions Limited | Information & communication | 2018 |
| Eight Little Feet Ltd | Arts & recreation | 2022 |
| Eisa Kamf Limited | Transport & logistics | 2019 |
| EJE Consultancy Limited | Professional & scientific | 2016 |
| EJE Properties Limited | Real estate | 2012 |
| EJM Services Ltd | Construction | 2022 |
| EKD Solutions Limited | Extraterritorial | 2016 |
| Ekenas Ltd | Other services | 2019 |
| Ekoklean Ltd | Administrative & support | 2016 |
| Ekomarkt Ltd | Wholesale & retail | 2024 |
| EL Beauty & Therapy Ltd | Other services | 2024 |
| Elaba Ltd | Other services | 2020 |
| Elaris Healthcare Services Limited | Information & communication | 2026 |
| Elbato Ltd | Administrative & support | 2019 |
| Elbeo UK Limited | Professional & scientific | 2010 |