| Driftwood Daze Limited | Real estate | 2018 |
| Drink Plus Ltd | Wholesale & retail | 2023 |
| Driscoll Clarke Limited | Administrative & support | 2011 |
| Drive Community Ltd | Extraterritorial | 2025 |
| Drive Recruit Limited | Administrative & support | 2020 |
| Driven Motor Club Ltd | Administrative & support | 2025 |
| Driving Instructor Services Limited | Administrative & support | 2011 |
| DRJ Accountants Limited | Professional & scientific | 2024 |
| Drjd (UK) Limited | Professional & scientific | 2021 |
| DRM Holdings Limited | Real estate | 2020 |
| DRM Real Estate Limited | Real estate | 2016 |
| Drop Bear Beer Co. Ltd | Manufacturing | 2019 |
| Drovers Arms Hotel Ltd | Hospitality | 2019 |
| DRS FM Services Limited | Manufacturing | 2013 |
| DRT Financial Services Limited | Financial services | 2023 |
| DRTC2 Ltd | Wholesale & retail | 2024 |
| Drug Dogs (UK) Limited | Other services | 2001 |
| Drummau House Ltd | Professional & scientific | 2021 |
| Dryad Bushcraft CIC | Education | 2019 |
| Dryhouse Group Ltd | Construction | 2024 |
| DSA Clothing Manufacturing Limited | Manufacturing | 2024 |
| DSA Manufacturing Limited | Wholesale & retail | 2014 |
| Dsas Properties Ltd | Real estate | 2022 |
| DSB Lighting Ltd | Information & communication | 2023 |
| DSC Food and Wine Ltd | Wholesale & retail | 2025 |
| DSD95 Holdings Limited | Financial services | 2026 |
| DSG Refurbishment Limited | Construction | 2011 |
| DSJ Operations Limited | Wholesale & retail | 2013 |
| DSL Technical Engineering Ltd | Manufacturing | 2020 |
| Dswproperty Rentals Ltd | Real estate | 2025 |
| Dtale Group Ltd | Information & communication | 2024 |
| DTE Electrical Limited | Construction | 2014 |
| DTJ Holdings Limited | Financial services | 2024 |
| Dtlk Limited | Hospitality | 2024 |
| DTR Medical Limited | Manufacturing | 2002 |
| Dtre Ltd | Real estate | 2025 |
| DTW (SPV) Limited | Real estate | 2008 |
| Dubaissi Estates LLP | | 2016 |
| Dubaissi Properties Limited | Real estate | 2019 |
| Dubbers Delight Ltd | Wholesale & retail | 2018 |
| Duck & Dough Ltd | Hospitality | 2025 |
| Duct Cleaning Solutions Ltd | Administrative & support | 2021 |
| Dukefield Investments Limited | Extraterritorial | 1994 |
| Dukefield Properties Limited | Administrative & support | 2011 |
| Dukes Meiya Art Gallery Ltd | Wholesale & retail | 2023 |
| Dulais Inns Ltd | Hospitality | 2018 |
| Dulais Investments Limited | Hospitality | 2017 |
| Dulais Kebab Ltd | Hospitality | 2026 |
| Dulais Pizza Ltd | Hospitality | 2023 |
| Dulais Valley Developments Limited | Construction | 2017 |
| Dumaka Limited | Health & social care | 2012 |
| Dunn Landscapes Limited | Administrative & support | 2003 |
| Dunne Properties Ltd | Real estate | 2017 |
| Duramax Plumbing Limited | Construction | 2025 |
| Durel Industrial and Ecological Products Ltd | Wholesale & retail | 2025 |
| Durmech Engineering Limited | Manufacturing | 2007 |
| Dusty's Pizza Ltd | Hospitality | 2015 |
| Dutchi Ltd | Information & communication | 2022 |
| Dutton Jones Associates (2003) Limited | Professional & scientific | 2003 |
| DV Catering Ltd | Hospitality | 2023 |
| DV Hotel Limited | Hospitality | 2020 |
| DV Original Ltd | Manufacturing | 2025 |
| DV26 Developments Ltd | Real estate | 2025 |
| DW Dietetics Ltd | Other services | 2024 |
| Dw-Air Limited | Construction | 2018 |
| DWJ Group Limited | Information & communication | 2016 |
| DWJ Wealth Management Limited | Financial services | 2014 |
| DWR Natural Water Co., Ltd | Manufacturing | 2015 |
| DWS (S.W.Wales) Limited | Other services | 2019 |
| DWS Bar and Catering Limited | Other services | 2017 |
| DWS Payroll Services Limited | Hospitality | 2022 |
| DWS PUB Co. Limited | Hospitality | 2011 |
| DWS PUB Management Limited | Other services | 2017 |
| DWS Wholesale Limited | Wholesale & retail | 2013 |
| DWT Process Limited | Administrative & support | 2015 |
| DWY Afon Ltd | Hospitality | 2023 |
| Dyfed Developments SPV 1 Ltd | Construction | 2022 |
| Dyfed Developments SPV 2 Ltd | Construction | 2022 |
| Dyma DY Ltd | Real estate | 2021 |
| Dynamic Bookings & Promotions Limited | Arts & recreation | 2021 |
| Dynamic Gases Limited | Wholesale & retail | 2013 |
| Dynamic Rock Adventures Ltd | Arts & recreation | 2008 |
| Dynamiprix Limited | Information & communication | 2026 |
| Dyslexiaactionwales Ltd | Education | 2017 |
| DZ3 Group Ltd | Professional & scientific | 2024 |
| E & D Property Group Ltd | Real estate | 2024 |
| E & E Global Ltd | Wholesale & retail | 2025 |
| E & S Cars Limited | Transport & logistics | 2016 |
| E a C Technical Services Limited | Energy | 2026 |
| E Cigarette Direct Limited | Wholesale & retail | 2015 |
| E Cigs 2 Go (Kingsheath) Limited | Wholesale & retail | 2014 |
| E Commerce Accounting and Tax Specialists Limited | Extraterritorial | 2022 |
| E Creative Limited | Information & communication | 2006 |
| E Cursio Ltd | Other services | 2023 |
| E Davies Limited | Construction | 2020 |
| E Edwin Daniel Ltd | Transport & logistics | 2026 |
| E J G Harris Driver Ltd | Transport & logistics | 2026 |
| E J Landscapes Properties Swansea Limited | Construction | 2017 |
| E L Carpentry Ltd | Construction | 2022 |
| E Living Letting Ltd | Real estate | 2021 |