| Recruit.Bio Ltd | Information & communication | 2023 |
| Recycle to Save Waste Limited | Water & waste | 2021 |
| Recycling Process Developments Limited | Water & waste | 2008 |
| Redken Ltd | Information & communication | 2014 |
| Redmond Recycling Limited | Water & waste | 2020 |
| Reedland Ventures Limited | Construction | 2023 |
| REI Investment Ltd | Real estate | 2025 |
| Remus-Gabriel Iordache Ltd | Transport & logistics | 2024 |
| Research Evaluation Consulting Limited | Professional & scientific | 2023 |
| Resolution Scaffolding Ltd | Extraterritorial | 2024 |
| Retrospect Enterprise Computing Services Limited | Information & communication | 2019 |
| Revive Carpet and Upholstery Cleaning Ltd | Administrative & support | 2024 |
| Revive Property Care Ltd | Real estate | 2026 |
| Rhea Events Ltd | Other services | 2022 |
| Rhoyal GEM Empire Ltd | Real estate | 2025 |
| Rica Homestyle Limited | Manufacturing | 2020 |
| Ridge Financials Ltd | Professional & scientific | 2022 |
| Riseley Limited | Health & social care | 2026 |
| RML Painting & Decorating Limited | Construction | 2019 |
| Rodofilms Ltd | Information & communication | 2016 |
| Roopra & Sons Construction Ltd | Construction | 2026 |
| Rpantos Ltd | Extraterritorial | 2024 |
| RS Dawe Limited | Wholesale & retail | 2008 |
| RTF 87 Limited | Wholesale & retail | 2018 |
| RTS Waste Management Limited | Water & waste | 2006 |
| Ruby’S Roses Ltd | Wholesale & retail | 2025 |
| Russy Ltd | Construction | 2026 |
| Rusu Trans Ltd | Transport & logistics | 2015 |
| Ruzach-Praise UK Ltd | Health & social care | 2011 |
| Ryan Kaye Consulting Ltd | Administrative & support | 2016 |
| Ryken Studios Limited | Arts & recreation | 2023 |
| Ryzer Wealth Corp Limited | Information & communication | 2025 |
| RZV Electrical Ltd | Construction | 2026 |
| S Parker Asset Management Ltd | Extraterritorial | 2024 |
| S&G Carpentry Kent Ltd | Manufacturing | 2026 |
| Saarah Catering Ltd | Hospitality | 2024 |
| Sacred Heart Healthcare Services Ltd | Health & social care | 2023 |
| Safepath UK Consulting Limited | Professional & scientific | 2017 |
| Saint Healthcare Services Limited | Health & social care | 2023 |
| Sakshad Ltd | Information & communication | 2023 |
| Samdavee Ltd | Health & social care | 2025 |
| Samtee Ltd | Wholesale & retail | 2025 |
| Sanatana Real Estate Ltd | Real estate | 2025 |
| Sandhus Convience Store Ltd | Wholesale & retail | 2017 |
| Sands & Arches Homes Ltd | Real estate | 2020 |
| Sanusi Triumph Ltd | Wholesale & retail | 2024 |
| Savimati Healthcare Limited | Health & social care | 2022 |
| Savour Eats Ltd | Hospitality | 2019 |
| SBO& Co Ltd | Wholesale & retail | 2026 |
| SBT Domestics Ltd | Other services | 2019 |
| SC Ciornei Ltd | Transport & logistics | 2019 |
| Seanbraylens Ltd | Health & social care | 2022 |
| SECUR1414 Limited | Information & communication | 2015 |
| Seed Tech & Media Ltd | Information & communication | 2020 |
| Seluné Limited | Administrative & support | 2023 |
| Seravia Health Limited | Health & social care | 2025 |
| Sereena Ltd | Health & social care | 2022 |
| Serford Services Limited | Health & social care | 2019 |
| Serveline Ltd | Administrative & support | 2024 |
| Sestos Limited | Information & communication | 2009 |
| Setiif Becks Ltd | Public administration | 2025 |
| Setiif Beks Ltd | Health & social care | 2025 |
| Seyvom Ltd | Information & communication | 2022 |
| Sfsj Tech Ltd | Information & communication | 2025 |
| Shalom ELI Limited | Administrative & support | 2019 |
| Shambare Limited | Health & social care | 2021 |
| Shekinah Glory Consulting Limited | Professional & scientific | 2025 |
| Shineonsolarpanels Ltd | Manufacturing | 2025 |
| Shubham DEV Limited | Wholesale & retail | 2025 |
| Siadem Ltd | Professional & scientific | 2018 |
| Silk Route Global Limited | Wholesale & retail | 2017 |
| Silveraxon Ltd | Information & communication | 2026 |
| Simography Ltd | Professional & scientific | 2025 |
| Simpson Solutions Ltd | Professional & scientific | 2005 |
| Sisi EKO Ltd | Other services | 2024 |
| SJ Strunkey Carpentry and Joinery Ltd | Construction | 2024 |
| Sjayz Limited | Hospitality | 2023 |
| Sjvj Ltd | Wholesale & retail | 2026 |
| Skaree Ltd | Real estate | 2024 |
| Skillful Scaffolding Ltd | Construction | 2015 |
| Skillselectricalservices Ltd. | Energy | 2017 |
| SKM WIN Medical Limited | Health & social care | 2024 |
| Sladens Ltd | Real estate | 2014 |
| SLE Framing Limited | Construction | 2018 |
| Smart Logistics Group Ltd | Transport & logistics | 2021 |
| Smartsafe Fire and Security Ltd | Public administration | 2025 |
| Snogwill Ltd | Health & social care | 2019 |
| Solar Intelligence Ltd | Construction | 2023 |
| Solar Recycling Solutions Limited | Water & waste | 2024 |
| Solar Renewables Ltd | Construction | 2024 |
| Solt Engineering Ltd | Professional & scientific | 2026 |
| Solt Property Ltd | Real estate | 2022 |
| Solvexo Ltd | Construction | 2024 |
| Sound Mind International Ltd | Health & social care | 2021 |
| South East Secret Ltd | Wholesale & retail | 2025 |
| Southern Cutters Limited | Manufacturing | 2018 |
| Spacex Properties Limited | Real estate | 2026 |
| Spectrum Thrive Ltd | Health & social care | 2026 |
| Springfield Invicta Ltd | Professional & scientific | 2017 |
| ST. Gabriel Property Lettings Limited | Real estate | 2024 |