| Elmside Developments Ltd | Construction | 2025 |
| Elmstone Lifestyle Limited | Wholesale & retail | 2016 |
| ELP Consulting Limited | Professional & scientific | 2024 |
| Elpida Kennedy Group Limited | Wholesale & retail | 2018 |
| Eluciant Limited | Administrative & support | 2017 |
| Elusive Properties Ltd | Real estate | 2020 |
| Elysea Wellness&Spa Ltd | Wholesale & retail | 2025 |
| Elyssadavid Ltd | Health & social care | 2021 |
| EM & C Project Ltd | Construction | 2014 |
| Emad - RAD Ltd | Health & social care | 2025 |
| Emak Limited | Construction | 2008 |
| Emarket Trading Ltd | Wholesale & retail | 2021 |
| Embuy Ltd | Construction | 2022 |
| Emcc Global Consortium UK PVT Limited | Professional & scientific | 2022 |
| Emcee Associates Limited | Construction | 2016 |
| Emergency Roofing Ltd | Construction | 2018 |
| Emeritos Cleaning Limited | Administrative & support | 2025 |
| Emersion Design Ltd | Real estate | 2022 |
| EMI & Bobi Ltd | Wholesale & retail | 2022 |
| Eminence Consulting Services Limited | Information & communication | 2016 |
| Emma GT Properties Limited | Real estate | 2024 |
| Emma Guns Limited | Other services | 2018 |
| Emmedith Care Limited | Health & social care | 2017 |
| Emmizzy Limited | Financial services | 2021 |
| Emogen Ltd | Hospitality | 2017 |
| Emperor UK Management Ltd | Hospitality | 2026 |
| Empire Consulting Solutions Ltd | Information & communication | 2014 |
| Empresario Limited | Professional & scientific | 2014 |
| Empress of India (Sutton) Ltd | Real estate | 2002 |
| Emtech Recruitment Limited | Administrative & support | 2020 |
| Emzo Property Ltd | Real estate | 2024 |
| Enamour Dental Clinic Limited | Health & social care | 2021 |
| Enchantée Ltd | Administrative & support | 2024 |
| Encofact Properties SPV Ltd | Real estate | 2016 |
| Endpoint Technologies Ltd | Information & communication | 2025 |
| Endzone Sports Ltd | Education | 2020 |
| Energ-Eyes Limited | Construction | 2014 |
| Enervit Nutrition Limited | Administrative & support | 2018 |
| Enever Surveyors Ltd | Other services | 2018 |
| Enfant Unique Films Ltd | Information & communication | 2019 |
| Engineering Everyone Ltd | Extraterritorial | 2022 |
| Engintec Limited | Wholesale & retail | 2020 |
| ENGX3C Consultancy Limited | Professional & scientific | 2025 |
| Engytec Ltd | Manufacturing | 2019 |
| Enhance Design & Build Limited | Construction | 2014 |
| Enigmaze Ltd | Other services | 2022 |
| Enmore Lodge Limited | Health & social care | 1985 |
| Enoch Solutions Limited | Professional & scientific | 2023 |
| Enorex Ltd | Professional & scientific | 2018 |
| Enotrac UK Limited | Information & communication | 1992 |
| Enso Insight Limited | Professional & scientific | 2025 |
| ENT Surgery Solutions Ltd | Manufacturing | 2025 |
| Entail Engineering Limited | Construction | 2022 |
| Entelligence Ltd | Information & communication | 2026 |
| Enterprise 68 Limited | Transport & logistics | 2023 |
| Environmental Clearance Services UK Limited | Water & waste | 2018 |
| Environmental Site Supplies Limited | Wholesale & retail | 2000 |
| Envoi London Ltd | Real estate | 2025 |
| Eoli Ltd | Wholesale & retail | 2023 |
| EON Car Services Ltd | Transport & logistics | 2021 |
| EP Hair Ltd | Other services | 2025 |
| Epapilo Limited | Wholesale & retail | 2021 |
| Epic Scaffolding Limited | Administrative & support | 2019 |
| Epicroyale Ltd | Information & communication | 2018 |
| EPM Dynamics Ltd | Information & communication | 2025 |
| Epochtree Ltd | Information & communication | 2013 |
| Epsilon Logistics Limited | Transport & logistics | 2020 |
| Epsom Conservatories Limited | Wholesale & retail | 2006 |
| Epsom Plant Hire Limited | Administrative & support | 2020 |
| Equicise Ltd | Education | 2015 |
| Equity Brands Limited | Administrative & support | 2020 |
| ERA Properties Ltd | Real estate | 2023 |
| Ergo Electrical Services Partnership Limited | Construction | 2012 |
| Ergo Maintenance and Refurbishment Limited | Construction | 2017 |
| Eriira Ltd | Information & communication | 2026 |
| Erin Taverns Ltd | Hospitality | 2010 |
| Ermelo Parent Limited | Administrative & support | 2021 |
| Errores Solution Technologies Ltd | Wholesale & retail | 2024 |
| ES Construction & Maintenance Ltd | Construction | 2024 |
| ES Group International Holdings Limited | Information & communication | 2025 |
| Escape From the Room Limited | Arts & recreation | 2024 |
| ESH UK Limited | Administrative & support | 2007 |
| Esher Financial Services Limited | Professional & scientific | 2023 |
| ESM Management Limited | Health & social care | 2009 |
| ESP Leisure Limited | Information & communication | 1990 |
| ESPERANZA16 Limited | Administrative & support | 2025 |
| ESS Railing Ltd | Manufacturing | 2018 |
| Essentia Properties Ltd | Real estate | 2019 |
| Essential Services (Surrey) Limited | Construction | 2003 |
| Essi &SON Co Ltd | Real estate | 2020 |
| Estethica CIC | Professional & scientific | 2022 |
| Esther Limited | Administrative & support | 2007 |
| Esto Properties Limited | Real estate | 2023 |
| Estudio Flores Ltd | Wholesale & retail | 2026 |
| Esvath Cloud Solutions Ltd | Information & communication | 2022 |
| ET3 Limited | Real estate | 2018 |
| Eternis Holdings Ltd | Professional & scientific | 2025 |
| Ethereal Prosperity Limited | Real estate | 2019 |
| Ethical Promotional Product Strategic Alliance Ltd | Other services | 2017 |
| Ethicare Dental Limited | Health & social care | 2022 |