| Tyre Centre Direct Ltd | Wholesale & retail | 2016 |
| Tyres on Move Ltd | Other services | 2026 |
| TYS Lichfield Ltd | Hospitality | 2023 |
| TZ2 Consultancy Ltd | Professional & scientific | 2022 |
| Tzitzikas Limited | Hospitality | 2026 |
| U.F.D. Limited | Extraterritorial | 1957 |
| Ubhi Design & Build Ltd | Construction | 2017 |
| Ubhi Pharmacy Limited | Wholesale & retail | 1996 |
| Ubhi Property Ltd | Financial services | 2025 |
| Ubhis Investments Ltd | Real estate | 2025 |
| UBU (Sutton Coldfield) Limited | Other services | 2008 |
| UC 4 Ltd | Information & communication | 1999 |
| UF Foods Ltd | Wholesale & retail | 2026 |
| UHF Ltd | Health & social care | 2021 |
| UHG Limited | Real estate | 2025 |
| UK & Ireland Paediatric Professionals of Pakistani Origin Ltd | Health & social care | 2025 |
| UK Blinds Birmingham Limited | Wholesale & retail | 2017 |
| UK Corporate Polo Ltd | Administrative & support | 2026 |
| UK Funerals Limited | Extraterritorial | 1957 |
| UK Gate Ltd | Administrative & support | 2025 |
| UK Grand Motors Ltd | Wholesale & retail | 2025 |
| UK Medical Services LLP | | 2025 |
| UK Morris Blinds Ltd | Manufacturing | 2019 |
| UK Prop Invest Limited | Construction | 2021 |
| UK Propserve Limited | Administrative & support | 2007 |
| UK Retails Ltd | Wholesale & retail | 2025 |
| UKF Limited | Extraterritorial | 1986 |
| Ukpalletservices Limited | Transport & logistics | 2018 |
| Uktvparts Limited | Other services | 2010 |
| ULA Holdings Ltd | Financial services | 2022 |
| Ulex Property Limited | Real estate | 2026 |
| Ulogix Limited | Information & communication | 2007 |
| Ultimate Driving Adventures Limited | Hospitality | 2023 |
| Ultimate Reach Limited | Arts & recreation | 2015 |
| Ultrasonic Limited | Administrative & support | 2021 |
| UN & UT Health Care Limited | Information & communication | 2021 |
| Unask Ltd | Real estate | 2026 |
| Uncle James.Com Ltd | Wholesale & retail | 2014 |
| Under Pressure Espresso Limited | Hospitality | 2016 |
| Underground Pipe Moling Services Ltd | Professional & scientific | 2015 |
| Unica Concepts Ltd | Administrative & support | 2010 |
| Unicorn Resourcing Limited | Administrative & support | 2022 |
| Uniform Hub Ltd | Manufacturing | 2014 |
| Unilak Estates Ltd | Real estate | 2021 |
| Unique 1 Health & Fitness Limited | Health & social care | 2013 |
| Unique Drives & Patios Limited | Construction | 2013 |
| Unique Fried Chicken and Pizza Ltd | Hospitality | 2025 |
| Unique Roofing & Driveways Limited | Construction | 2023 |
| Unique Software Services Ltd | Information & communication | 2017 |
| Unique Style Fashion Limited | Wholesale & retail | 2007 |
| UNIQUE3 Ltd | Arts & recreation | 2026 |
| Unit 2 Ltd | Real estate | 2025 |
| United Tyre Group Ltd | Wholesale & retail | 2025 |
| Unity Nurseries Limited | Education | 2022 |
| Universal Heat Transfer Limited | Manufacturing | 2020 |
| Universal Services Trading Ltd. | Transport & logistics | 2015 |
| Universal World Ltd | Wholesale & retail | 2024 |
| Unless Procurement Ltd | Professional & scientific | 2024 |
| Unlikely Story Limited | Information & communication | 2023 |
| Unlocking Strengths Ltd | Professional & scientific | 2018 |
| Unlocking Voices CIC | Education | 2014 |
| Unpossible AI Ltd | Wholesale & retail | 2024 |
| Unreal Property Investments Limited | Real estate | 2024 |
| Unstoppable 36 Ltd | Arts & recreation | 2020 |
| Updates Media Limited | Information & communication | 2015 |
| Upgrade Joinery Ltd | Construction | 2024 |
| Upper Clifton Ltd | Professional & scientific | 2024 |
| Upper Clifton Road Developments Limited | Real estate | 2023 |
| Upright Wellness Limited | Health & social care | 2016 |
| Upsteps Limited | Real estate | 2018 |
| Upstream Charitable Trust | Other services | 2015 |
| Upton Transport Services Limited | Transport & logistics | 2015 |
| Upward Holdings Ltd | Financial services | 2015 |
| UQB Limited | Health & social care | 2016 |
| UR Laser Girl Ltd | Other services | 2024 |
| Urban Accounts Ltd | Other services | 2017 |
| Urban Garden Space Ltd | Wholesale & retail | 2022 |
| Urban Installation Electrical Ltd | Energy | 2013 |
| Urban Installations Birmingham Ltd | Construction | 2025 |
| Urban Room Designs Limited | Professional & scientific | 2021 |
| Urban Village CAP1 Limited | Financial services | 2018 |
| Urswick Trading Ltd | Professional & scientific | 2020 |
| US Dental Ltd | Health & social care | 2024 |
| USR Investments Ltd | Real estate | 2025 |
| USTAFF360 Limited | Administrative & support | 2023 |
| Uthfitt Ltd. | Arts & recreation | 2010 |
| UTR Property Developments Ltd | Construction | 2019 |
| Utsav Limited | Arts & recreation | 2014 |
| UV Investments Ltd | Real estate | 2017 |
| UV Management Ltd | Real estate | 2015 |
| UV SC Kidderminster Limited | Construction | 2020 |
| UV SC Stafford Limited | Construction | 2020 |
| UXY Labs Limited | Information & communication | 2014 |
| Uzzapp Ltd | Wholesale & retail | 2021 |
| V and R Healthcare Ltd | Health & social care | 2026 |
| V Jewellery Limited | Wholesale & retail | 1998 |
| V Pirvu Services Limited | Construction | 2019 |
| V Singh Ltd | Wholesale & retail | 2020 |
| V Somerford Ltd | Construction | 2020 |
| V Sung Limited | Health & social care | 2010 |