| Emerging Solutions Product Lines Limited | Other services | 1997 |
| Emfran Ltd | Professional & scientific | 2016 |
| Emils Engineering Ltd | Construction | 2025 |
| Eminasolutions Limited | Professional & scientific | 2024 |
| Emma's Dance Academy Limited | Other services | 2020 |
| Emmanuel Properties (Sutton) Limited | Real estate | 2013 |
| Emmanuel TAM & Sun Limited | Hospitality | 2022 |
| Emmatom Properties Ltd | Real estate | 2003 |
| Emotional Connection Ltd | Other services | 2015 |
| EMPACT4LIFE Ltd | Health & social care | 2024 |
| Empire Appliances Limited | Wholesale & retail | 2017 |
| Empower Coaching Ltd | Education | 2023 |
| Empower Poetry CIC | Education | 2022 |
| Empress Ballet Limited | Education | 2017 |
| Empress Beauty Lounge Limited | Other services | 2018 |
| Encoders UK Holdings Limited | Financial services | 2024 |
| Encoders UK Limited | Manufacturing | 1994 |
| Encore Family Office Limited | Financial services | 2014 |
| Endecay Professional Development Ltd | Administrative & support | 2026 |
| Endometriosis Experts Limited | Health & social care | 2022 |
| Energycode Limited | Administrative & support | 2013 |
| Energysave Nationwide Ltd | Administrative & support | 2012 |
| Engage Dementia Limited | Health & social care | 2023 |
| Engeneva Consulting Ltd | Professional & scientific | 2010 |
| Engineering Compliance Solutions Ltd | Professional & scientific | 2020 |
| Engrec Solutions Ltd | Administrative & support | 2025 |
| Enhanced Developments Limited | Construction | 2009 |
| Enhanced Polished Concrete Limited | Construction | 2013 |
| Enko’S Vision Ltd | Hospitality | 2021 |
| Enniscrone Dental Laboratory Limited | Health & social care | 1975 |
| Enoki Flooring and Tiling Limited | Construction | 2022 |
| Enoki Limited | Construction | 2011 |
| Enovision Ltd | Information & communication | 2011 |
| Enovo Properties Ltd | Real estate | 2022 |
| Enpotential Limited | Professional & scientific | 2007 |
| Enterec Limited | Administrative & support | 2021 |
| Enterpreyes Ltd | Health & social care | 2024 |
| Enterprise Electric Projects Ltd | Construction | 2016 |
| Enterprise FD Limited | Professional & scientific | 2018 |
| Entert@Inment Solutions Ltd | Arts & recreation | 2022 |
| Entropyworks Limited | Information & communication | 2014 |
| Envee Limited | Professional & scientific | 2011 |
| Enviro-Safe Holdings Limited | Real estate | 2007 |
| Enviro-Safe Limited | Construction | 1998 |
| Enviro-Safe Services Limited | Extraterritorial | 2007 |
| Envirofood and Health Ltd | Manufacturing | 2024 |
| Environan Developments Limited | Construction | 2018 |
| Environan Power Generation Limited | Professional & scientific | 2019 |
| Environmental Pest Control Limited | Administrative & support | 2014 |
| Environmental Tax Solutions Ltd | Professional & scientific | 2023 |
| Envo Energy Ltd | Construction | 2025 |
| EOB Services Limited | Construction | 2016 |
| EOS Surveyors Ltd | Professional & scientific | 2010 |
| EOS Toronto Planning Limited | Construction | 2024 |
| Epechs Ltd | Education | 2022 |
| Ephrym IT Consulting Limited | Information & communication | 2013 |
| Ephyrm Healthcare Services Ltd | Real estate | 2018 |
| Epost Express Limited | Transport & logistics | 2019 |
| Epsilon E4 Ltd | Professional & scientific | 2018 |
| EQ Care Hastings Limited | Construction | 2021 |
| EQ Longbuckby Holdings Limited | Construction | 2018 |
| EQM Distribution Limited | Wholesale & retail | 2025 |
| Equipmach Ltd | Manufacturing | 2017 |
| Equipoint P2 Ltd | Construction | 2019 |
| Equipoint Property Management Ltd | Construction | 2017 |
| Equitas Global Health Limited | Professional & scientific | 2025 |
| ERE Property Investment Ltd | Real estate | 2021 |
| Ereisis Limited | Professional & scientific | 2010 |
| ERI Consulting Ltd | Professional & scientific | 2023 |
| ERP Logic Limited | Information & communication | 2014 |
| Errgo Ltd | Professional & scientific | 2023 |
| ESA Motor Company Limited | Wholesale & retail | 2026 |
| Eshtiaque Ltd | Transport & logistics | 2023 |
| Eskay Homes Ltd | Hospitality | 2012 |
| Eskimo Technology Ltd | Information & communication | 2009 |
| Esmae Lilly Ltd | Real estate | 2019 |
| Esmail Ltd | Hospitality | 2018 |
| Espetada Ltd | Hospitality | 2020 |
| Espree Limited | Wholesale & retail | 2001 |
| Espresso Yourself UK Limited | Hospitality | 2015 |
| Essential Care Recruitment Ltd | Administrative & support | 2025 |
| Estate Wallet Limited | Professional & scientific | 2025 |
| Estella & Associates Limited | Extraterritorial | 2013 |
| Estenidas Ltd | Administrative & support | 2020 |
| ETA Limited | Wholesale & retail | 2014 |
| Etchd Ltd | Wholesale & retail | 2026 |
| Eterna Health Limited | Health & social care | 2025 |
| Ethical Adviser(Uk) Ltd | Financial services | 2018 |
| Ethos Leadership Limited | Education | 2023 |
| Etme Investments Ltd | Construction | 2024 |
| ETR Vtouch Limited | Information & communication | 2021 |
| Etra Capital Limited | Financial services | 2024 |
| EU52 Ltd | Professional & scientific | 2026 |
| Eudaimonia Assets Ltd | Financial services | 2024 |
| Eurelo Limited | Transport & logistics | 2023 |
| Euro Mini Market 2 Ltd | Wholesale & retail | 2026 |
| Eurologos Limited | Professional & scientific | 2003 |
| European General Galvanizers Association | Other services | 1991 |
| Euroshowers (Midlands) Limited | Construction | 2002 |
| Euroshowers (UK) Limited | Construction | 2009 |