| D2 Assets Limited | Wholesale & retail | 2026 |
| D5 Investments Limited | Real estate | 2020 |
| D6 Properties Ltd | Real estate | 2017 |
| D60 Skip Hire Ltd | Water & waste | 2022 |
| DA Ponda Ltd | Real estate | 2025 |
| Dacy.Ai Ltd | Information & communication | 2025 |
| Daeja Consulting Limited | Professional & scientific | 2025 |
| Daily Grind Official Ltd | Wholesale & retail | 2022 |
| Daisy Chains Properties Ltd | Real estate | 2023 |
| Daisy Nails and Aesthetics Ltd | Other services | 2023 |
| Dakus Construct Ltd | Construction | 2020 |
| Dale Monk Limited | Real estate | 1964 |
| Dale Raymond Thomason Ltd | Extraterritorial | 2021 |
| Dalexia Limited | Hospitality | 2014 |
| Dalia Nutrition Limited | Health & social care | 2021 |
| Dalian Trading Corporation Ltd | Real estate | 2013 |
| Dallaswylde Recruitment Ltd | Administrative & support | 2020 |
| Daltec Contractors Limited | Professional & scientific | 2024 |
| Dalton NET Service Ltd | Information & communication | 2014 |
| Daly and Company Limited | Extraterritorial | 1890 |
| Damage Reclaim Limited | Administrative & support | 2017 |
| Damp-Tech (Midlands) Limited | Construction | 2011 |
| DAN General Builder Ltd | Construction | 2025 |
| DAN Johnston Software Ltd | Information & communication | 2019 |
| Danarsh Limited | Health & social care | 2011 |
| Dance Holdings Limited | Real estate | 2025 |
| DANCE4U Inclusive Arts CIC | Education | 2023 |
| Daniel Hurd Associates Limited | Other services | 2014 |
| Daniel Ross Funerals Limited | Other services | 2009 |
| Danjoeli Consulting Limited | Construction | 2014 |
| Danstransport Ltd | Transport & logistics | 2025 |
| Danyi Building & Decorating Ltd | Construction | 2012 |
| Danymay Properties Ltd | Real estate | 2022 |
| Darcey MAE Creative Ltd | Arts & recreation | 2025 |
| Darcy's Fish and Chips Limited | Hospitality | 2024 |
| Darcy's Tavern Limited | Hospitality | 2020 |
| Darfin Consultancy Limited | Professional & scientific | 2021 |
| Darfin Investments Limited | Administrative & support | 2016 |
| Darlaston Builders Merchants Limited | Administrative & support | 2014 |
| Darlaston Civils LLP | | 2014 |
| Darlsbury Limited | Real estate | 2021 |
| Darren Langley Limited | Administrative & support | 2012 |
| Darren W Faragher Limited | Other services | 2000 |
| Darrin 1471 Ltd | Wholesale & retail | 2018 |
| Darrin Perris Limited | Professional & scientific | 2012 |
| Dartmouth Property Investments Limited | Real estate | 2023 |
| DAT Group Ltd | Real estate | 2019 |
| Data Centre Portal Limited | Information & communication | 2016 |
| Data in Sport Ltd | Professional & scientific | 2024 |
| Datadecisions.Ai Ltd | Information & communication | 2025 |
| Datoria Limited | Wholesale & retail | 2025 |
| Datostech Limited | Information & communication | 2015 |
| Dattani Investments Limited | Real estate | 2016 |
| David B. Hendry Limited | Extraterritorial | 1994 |
| David Copland Consultancy Limited | Professional & scientific | 2020 |
| David Hetherington Legal Limited | Professional & scientific | 2017 |
| David Hillier Ltd | Information & communication | 2010 |
| David James Decor Limited | Construction | 2026 |
| David Silvey & SON Limited | Extraterritorial | 1984 |
| David Wadley Photographers Ltd | Other services | 2015 |
| Davies Fasteners Ltd | Manufacturing | 2023 |
| Davin Carpets Limited | Wholesale & retail | 2006 |
| Davina Lytton Coaching and Counselling Services Ltd | Health & social care | 2022 |
| Davinol Limited | Professional & scientific | 2025 |
| Davis Mcmullan Funeral Directors Limited | Extraterritorial | 2007 |
| Davisons Property Limited | Construction | 2022 |
| Davric North East Limited | Real estate | 1986 |
| Davy Developments Limited | Construction | 2000 |
| Dawn Till Dusk Films Ltd | Information & communication | 2025 |
| Dawneharrold Limited | Health & social care | 2025 |
| Day & Co Real Estate Ltd | Real estate | 2020 |
| Daykin Scott Accountants Ltd | Professional & scientific | 2024 |
| Dayoss Technologies Ltd | Information & communication | 2021 |
| Daytona Automotive Group Ltd | Wholesale & retail | 2022 |
| Daytona Motors Ltd | Wholesale & retail | 2026 |
| Daywood Limited | Hospitality | 2022 |
| DAZ Assets Ltd | Real estate | 2024 |
| DAZ Fish Bar Ltd | Hospitality | 2023 |
| Dazzling Dogs Limited | Other services | 2009 |
| DB Electrical Services (Birmingham) Limited | Construction | 2020 |
| DB Lofts Ltd | Manufacturing | 2024 |
| Dbammom Ltd | Professional & scientific | 2025 |
| DBM (Boldmere) Properties Limited | Real estate | 2021 |
| DBM (WB) Ltd | Extraterritorial | 2015 |
| DBR Consultancy Ltd | Information & communication | 2022 |
| DBS Accountancy Limited | Professional & scientific | 2016 |
| DBS Installations Limited | Administrative & support | 2025 |
| Dbsi Sprinkler Installations Limited | Manufacturing | 2015 |
| Dbydcreative Ltd | Professional & scientific | 2022 |
| DC Coaching Ltd | Health & social care | 2019 |
| DC Retail Services Limited | Professional & scientific | 2021 |
| DCA Consultancy Services Limited | Professional & scientific | 2018 |
| DDR (Rugby) Limited | Manufacturing | 1977 |
| DE Poel Creative Ltd | Professional & scientific | 2016 |
| De&De Support Limited | Hospitality | 2015 |
| De-Stress Therapy Ltd | Other services | 2023 |
| Dead Level Ltd | Information & communication | 2026 |
| Deadline Transfers Limited | Transport & logistics | 2021 |
| Deagee Connect Ltd | Information & communication | 2025 |
| Deals 4 U Outlet Ltd | Wholesale & retail | 2021 |