| S Class Construction UK Ltd | Construction | 2026 |
| S Jika Company Ltd | Extraterritorial | 2013 |
| S P Wills Ltd | Professional & scientific | 2022 |
| S&A Consultancy Services Ltd | Professional & scientific | 2019 |
| S&A Property Management Services Ltd | Real estate | 2021 |
| S&G Croydon Ltd | Real estate | 2020 |
| S&G D Properties Ltd | Real estate | 2023 |
| S&J Dental Ceramic LAB Limited | Health & social care | 2017 |
| S&Sons Consultancy Ltd | Administrative & support | 2023 |
| S.Baxter Risk Consulting Ltd | Financial services | 2023 |
| S.Lautomotiveprepandpaint Limited | Manufacturing | 2016 |
| S1 Management Services Limited | Manufacturing | 2007 |
| S24 Holdings Limited | Extraterritorial | 2015 |
| Saadat Limited | Real estate | 2022 |
| Saag London Ltd | Administrative & support | 2023 |
| Saas Management Services Ltd | Information & communication | 2021 |
| Sabat Associates Ltd | Professional & scientific | 2015 |
| Sabayjai (Surbiton) Limited | Health & social care | 2011 |
| Sachas & Associates Ltd | Professional & scientific | 2021 |
| Sachdeva Empire Ltd | Construction | 2025 |
| Sachdeva Investment Group Limited | Real estate | 2025 |
| SAF Professional Cleaning Services Limited | Administrative & support | 2013 |
| Safe-Sight Technology Ltd | Administrative & support | 2010 |
| Safety Floormasters Ltd | Construction | 2022 |
| Saffron Flame Ltd | Hospitality | 2026 |
| Saga Cake Limited | Wholesale & retail | 2021 |
| Sage Entertainment Inc Limited | Administrative & support | 2025 |
| Sage Pharmaceuticals Ltd | Health & social care | 2022 |
| Sahel Mining Company Limited | Administrative & support | 2017 |
| Sahel Mining Holdings Limited | Administrative & support | 2017 |
| Sailenmax Limited | Professional & scientific | 2008 |
| Sailing Solutions Limited | Real estate | 2020 |
| Saima & Alishba Properties Ltd | Real estate | 2026 |
| Saints SON Engineering Ltd | Manufacturing | 2025 |
| Salient Telecoms Limited | Information & communication | 2001 |
| Salim Khan Consulting Limited | Information & communication | 2014 |
| Salon NO.13 Limited | Other services | 2020 |
| Salter Studio Ltd | Manufacturing | 2026 |
| SAM Alberg Limited | Information & communication | 2013 |
| SAM Oliver Social Ltd | Information & communication | 2026 |
| Samah Clinical Ltd | Health & social care | 2025 |
| Samaran Limited | Financial services | 2018 |
| Samboo Healthcare Center Ltd | Other services | 2025 |
| Samko Accommodations Limited | Real estate | 2025 |
| Samko Capital Limited | Financial services | 2025 |
| Samko Clubs Limited | Other services | 2026 |
| Samko Clubs Property Limited | Real estate | 2026 |
| Samko Commodities Trading Limited | Wholesale & retail | 2026 |
| Samko Construction Limited | Construction | 2025 |
| Samko Holdings Limited | Financial services | 2023 |
| Samko Hospitality Limited | Hospitality | 2025 |
| Samko Industries Limited | Financial services | 2024 |
| Samko Kitchens Limited | Hospitality | 2025 |
| Samko Projects Limited | Financial services | 2024 |
| Samko Real Estate Holdings Limited | Real estate | 2025 |
| Samko Renewable Energy Limited | Financial services | 2025 |
| Samko Renewables Ltd | Financial services | 2024 |
| Samko Restaurants Leasing Limited | Real estate | 2026 |
| Samko Services Limited | Construction | 1996 |
| Samko Skavn Trading Limited | Wholesale & retail | 2026 |
| Samko Sram & Mram Bess Limited | Manufacturing | 2025 |
| Samko Suites Hospitality Limited | Hospitality | 2026 |
| Samko Suites Real Estate Holdings Limited | Real estate | 2026 |
| Samko Technologies Limited | Information & communication | 2025 |
| Samko Trading Limited | Wholesale & retail | 2026 |
| Sammy & Sally Limited | Administrative & support | 2009 |
| Samo Stories Ltd | Arts & recreation | 2018 |
| Sampo Forge Limited | Information & communication | 2023 |
| Samsound Limited | Information & communication | 2015 |
| Samwell Sage Ltd | Professional & scientific | 2025 |
| Sandberry Limited | Professional & scientific | 2023 |
| Sandringham Court (Twickenham) Limited | Households | 2004 |
| Sandringham Court Management Company Limited | Households | 1980 |
| Sandy Beauty and Academy Ltd | Other services | 2025 |
| Sandy Beauty and Skin Limited | Other services | 2026 |
| Sandy Beauty and Teach Ltd | Other services | 2026 |
| Sandy Clinic Signature Limited | Other services | 2026 |
| Sandy Elite Academy Limited | Other services | 2026 |
| Sandy Lane Residents Management Company Limited | Households | 2006 |
| Sanjiro Ltd | Information & communication | 2023 |
| Santa Cruz Developments Ltd | Professional & scientific | 2021 |
| Sants Construction Ltd | Construction | 2017 |
| Sapphire Accountancy (UK) Limited | Financial services | 2019 |
| Sapphire Homes (Birnbeck) Ltd. | Construction | 2004 |
| Sarah Bell Design Ltd | Professional & scientific | 2013 |
| Sarah Fretwell Communications Limited | Professional & scientific | 2019 |
| Sarwar Halal Butchers Ltd | Wholesale & retail | 2015 |
| Sash Windows Holdings Ltd | Financial services | 2024 |
| Sash Windows London Limited | Construction | 2005 |
| SAT NAV Travel Ltd | Administrative & support | 2009 |
| SATNAV4BUSINESS Ltd | Professional & scientific | 2008 |
| Sattya UK Ltd | Professional & scientific | 2025 |
| SAUMUVALUABLE2NDS Limited | Wholesale & retail | 2021 |
| Savage Project Consulting Ltd | Information & communication | 2025 |
| Saxon Mews (Kingston) Management Limited | Households | 1999 |
| SB Flowers Limited | Wholesale & retail | 2019 |
| SB Junior Ltd | Hospitality | 2017 |
| SB Marketing Management Consultancy Limited | Professional & scientific | 2013 |
| Sbcs World Limited | Professional & scientific | 2014 |
| Scaffdes Ltd | Professional & scientific | 2025 |