| Push-Fix Ltd | Manufacturing | 2025 |
| PVM Scaffolding Ltd | Construction | 2026 |
| PWINLATON25 Limited | Hospitality | 2025 |
| PWR Property Services Ltd | Construction | 2024 |
| PWS Electrical Contractor Ltd | Construction | 2016 |
| PWS Roofing Services Ltd | Construction | 2026 |
| Q'Vest Ltd | Construction | 2021 |
| Qascade Consulting Limited | Professional & scientific | 2024 |
| QE Aesthetics Ltd | Other services | 2025 |
| Qees Empire Ltd | Wholesale & retail | 2025 |
| Qhse Professional Services Ltd | Professional & scientific | 2016 |
| QPS NE Ltd | Real estate | 2025 |
| QSS (NE) Limited | Hospitality | 2013 |
| Qualifuse Ltd | Education | 2019 |
| Qualihealth Medicals Limited | Health & social care | 2024 |
| Qualitas Legal Limited | Professional & scientific | 2014 |
| Quality Budget Cars Ltd | Wholesale & retail | 2025 |
| Quality Concerns Limited | Professional & scientific | 2025 |
| Quality Controls NE Limited | Construction | 2024 |
| Quantum Commerce UK Ltd | Wholesale & retail | 2023 |
| Quantum Engineering Consultancy Ltd | Financial services | 2010 |
| Quantum Expertise Ltd | Professional & scientific | 2024 |
| Quartz Cleaning Ltd | Administrative & support | 2026 |
| Quatro North Limited | Real estate | 2014 |
| Quay Consult Ltd | Professional & scientific | 2022 |
| Quayside Exchange Land & Estates Limited | Real estate | 2024 |
| Qubuscontractsne Ltd | Construction | 2020 |
| Queen Street Heritage Trust Limited | Arts & recreation | 1997 |
| Quickroute Ltd | Transport & logistics | 2025 |
| Quokka Solutions Ltd | Energy | 2017 |
| Qureshi Autos Ltd | Wholesale & retail | 2026 |
| Qurum Health Ltd | Information & communication | 2019 |
| Qween UK Limited | Arts & recreation | 2026 |
| R & E North East Ltd | Real estate | 2024 |
| R & G Leisure Limited | Hospitality | 2025 |
| R & R Psychological and Psychotherapy Services Limited | Health & social care | 2008 |
| R & T Care Services Ltd | Health & social care | 2020 |
| R and a Properties County Durham Ltd | Hospitality | 2017 |
| R and C Promotions Ltd | Arts & recreation | 2019 |
| R and V Pharma Limited | Wholesale & retail | 2017 |
| R Hanby Electrical Limited | Construction | 2015 |
| R Iles and SON Ltd | Arts & recreation | 2022 |
| R J Construction & Development Limited | Real estate | 2006 |
| R Jefferson Financial Ltd | Financial services | 2015 |
| R Laws Property Limited | Real estate | 2026 |
| R N S Holdings Ltd | Financial services | 2025 |
| R Punshon Electrical Services Limited | Construction | 2016 |
| R T International Services Limited | Professional & scientific | 2018 |
| R W Farley Limited | Hospitality | 2003 |
| R&A&R Dodds Limited | Professional & scientific | 2025 |
| R&B Aquatics Ltd | Agriculture & fishing | 2025 |
| R&C (NE) Ltd | Hospitality | 2026 |
| R&D Plant Ltd | Administrative & support | 2026 |
| R&N Property Developments Limited | Real estate | 2022 |
| R.B Joinery Services Limited | Manufacturing | 2025 |
| R.M.H. (NE) Ltd | Construction | 2015 |
| Raaha Counselling Ltd | Health & social care | 2024 |
| Rabels Ltd | Administrative & support | 2017 |
| Rabjabpharma Ltd | Administrative & support | 2026 |
| Racedeck UK Limited | Extraterritorial | 2012 |
| Rachel Hutchinson Consultancy Ltd | Professional & scientific | 2026 |
| Rachel's Cleaning Services Ltd | Administrative & support | 2025 |
| Radha & Sons Ltd | Manufacturing | 2025 |
| Radhakrishnaa Ltd | Hospitality | 2025 |
| Radhi Empire Ltd | Hospitality | 2025 |
| Raf's PUB Ltd | Hospitality | 2020 |
| Rafi's Spice Ltd | Hospitality | 2018 |
| Rafid Power Company Ltd | Other services | 2022 |
| Rafsan Multiverse Ltd | Wholesale & retail | 2024 |
| Ragi Ventures Ltd | Wholesale & retail | 2025 |
| Ragvi Café & Bar Ltd | Hospitality | 2024 |
| Rahman Logistics Ltd | Transport & logistics | 2025 |
| Raid Founders Ltd | Wholesale & retail | 2025 |
| Rainbow North East Ltd | Administrative & support | 2017 |
| Rainbow United Ltd | Wholesale & retail | 2023 |
| Raindrops Medical Aesthetics Ltd | Other services | 2026 |
| Rainton Management Limited | Information & communication | 2008 |
| Raising Dough CIC | Manufacturing | 2022 |
| Raja Saeen Limited | Hospitality | 2017 |
| Rajdeep Holdings Ltd | Real estate | 2024 |
| Ralemco Holding Ltd | Financial services | 2025 |
| Ramathan Limited | Wholesale & retail | 2019 |
| Ramin Goals Limited | Wholesale & retail | 2025 |
| Rams Safety (North East) Ltd | Professional & scientific | 2021 |
| Ramu 23 Ltd | Manufacturing | 2025 |
| Rand Spaces Ltd | Real estate | 2025 |
| Range Windows Limited | Manufacturing | 2026 |
| Ranieh Ltd | Other services | 2018 |
| Rankerace Ltd | Wholesale & retail | 2025 |
| Rannerdale Media Ltd | Professional & scientific | 2022 |
| Ranya Shawarma Grill Ltd | Hospitality | 2025 |
| Raouf Food Ltd | Hospitality | 2026 |
| Rapid Responce Limited | Information & communication | 2015 |
| Rapid Response Tyres Ltd | Wholesale & retail | 2024 |
| Rapidfuture Limited | Real estate | 1986 |
| Rare Sportswear Ltd | Wholesale & retail | 2023 |
| Ratcliffe Group Building Contractors Ltd | Construction | 2024 |
| Rate Your Leader Limited | Information & communication | 2018 |
| Rathem Growler Limited | Construction | 2020 |
| Raveena Hylton Limited | Hospitality | 2025 |