| Netsky Controls Limited | Professional & scientific | 2021 |
| Network Automation Limited | Professional & scientific | 2003 |
| Neuro OT Limited | Health & social care | 2019 |
| Neuro WE CAN Ltd | Other services | 2025 |
| Neurokraken Studios Ltd | Information & communication | 2025 |
| Neurounity Training Ltd | Education | 2024 |
| Neutronics (NE) Limited | Manufacturing | 2004 |
| Neutronics EOT Limited | Extraterritorial | 2024 |
| Nevibes Ltd | Manufacturing | 2012 |
| New AGE Retrofit Limited | Real estate | 2023 |
| New ARK Construction Services Ltd | Construction | 2022 |
| New Asian Foods Ltd | Hospitality | 2012 |
| New Beginnings North CIC | Education | 2021 |
| New Breed Media Limited | Information & communication | 2018 |
| New Century Services Limited | Manufacturing | 1981 |
| New Dawn Property & Investment Limited | Real estate | 1998 |
| New Deck Flooring Limited | Construction | 2010 |
| New Glory U.K Ltd | Health & social care | 2025 |
| New Heights Rigging Limited | Construction | 2024 |
| New HK 24 Limited | Hospitality | 2019 |
| New Image Carpets Limited | Wholesale & retail | 2007 |
| New Leaf New Life Business Solutions CIC | Administrative & support | 2008 |
| New Level Gym Ltd | Arts & recreation | 2023 |
| New Mill 130 Limited | Hospitality | 2023 |
| New Mount Daisy Limited | Hospitality | 2025 |
| New Rocean Basket Ltd | Hospitality | 2023 |
| New Ryhope Legendz Barberz Limited | Other services | 2024 |
| New Ship PUB Limited | Hospitality | 2015 |
| New Vulcan Motors Limited | Manufacturing | 2014 |
| New World Designs Ltd | Arts & recreation | 2017 |
| Newbreed Global Services Ltd | Professional & scientific | 2024 |
| Newby's North Ltd | Hospitality | 2025 |
| Newcastle Carpets and Beds Limited | Wholesale & retail | 2021 |
| Newcastle Logistics Ltd | Transport & logistics | 2021 |
| Newcastleton Windfarm Limited | Energy | 2011 |
| Newcastleton Windfarm Partnership LLP | | 2011 |
| Newhaven QS Ltd | Professional & scientific | 2017 |
| Newman Barber Ltd | Other services | 2023 |
| NEWS2000 Limited | Wholesale & retail | 2025 |
| Newsline (NE) Ltd | Wholesale & retail | 2019 |
| Newton LEE Services Limited | Extraterritorial | 2014 |
| Nexelix Ltd | Wholesale & retail | 2026 |
| Nexgen Groundwork's & Construction Ltd | Construction | 2021 |
| Nexger Build Ltd | Construction | 2026 |
| Next Level North Ltd | Extraterritorial | 2020 |
| Next Wave Language Limited | Education | 2025 |
| NF Lukes Limited | Hospitality | 2021 |
| Nfpas Employee Ownership Trustee Limited | Financial services | 2024 |
| Nfpas Holdings Limited | Professional & scientific | 2019 |
| Nfpas Limited | Administrative & support | 2001 |
| NG Property Services North East Ltd | Construction | 2021 |
| NGC Systems Ltd | Information & communication | 2017 |
| NH Shareholdings Ltd | Professional & scientific | 2017 |
| Niche Competitions Ltd | Information & communication | 2026 |
| Nicholsons Building and Home Improvements Limited | Manufacturing | 2025 |
| Nickys & Hope Limited | Hospitality | 2024 |
| Nicola Wood Investments Ltd | Real estate | 2023 |
| Niel Signature Ltd | Manufacturing | 2025 |
| Niemann-Pick UK | Information & communication | 2011 |
| Nigeria Community Sunderland CIC | Other services | 2021 |
| Nigerian Women Community UK CIC | Administrative & support | 2025 |
| Nightingale Facilities Management Limited | Administrative & support | 2026 |
| Nine Rivers Group Limited | Real estate | 2022 |
| Ninesquare Systems Ltd | Education | 2004 |
| Nineteen UK Limited | Real estate | 2025 |
| NINETEEN28 Limited | Hospitality | 2024 |
| Nissan Trading Europe Limited | Wholesale & retail | 1990 |
| Nistech Ltd | Wholesale & retail | 2020 |
| Niyavaran Ltd | Extraterritorial | 2020 |
| NJ Bulota Ltd | Wholesale & retail | 2021 |
| NJ Quality Homes Ltd | Real estate | 2025 |
| NKILLEEN77 Limited | Arts & recreation | 2024 |
| Nljis Holdings Limited | Professional & scientific | 2013 |
| NMA Engineering Limited | Professional & scientific | 2026 |
| NO 6 Roker Terrace Management Company Ltd | Households | 2020 |
| NO Downtime Technologies Ltd | Information & communication | 2022 |
| NO Name Ltd | Wholesale & retail | 2018 |
| NO1 Advertising Ltd | Professional & scientific | 2018 |
| Noah Properties NE Ltd | Real estate | 2025 |
| Noblesse Direct Ltd. | Wholesale & retail | 1999 |
| Nobody Burger Ltd | Hospitality | 2024 |
| NOC Holdings Limited | Real estate | 2019 |
| Noeh Construction Ltd | Construction | 2010 |
| Nola Fall Protection Ltd | Construction | 2020 |
| Nomad Safety & Security Limited | Mining & quarrying | 2023 |
| Nor-Dem Limited | Construction | 1999 |
| Nora Propco Ltd | Real estate | 2025 |
| Norcroft Construction and Maintenance Limited | Construction | 2015 |
| Norfolk Hotel(Sunderland) Ltd | Hospitality | 2015 |
| Norfolk Street Arts Community Interest Company | Arts & recreation | 2019 |
| Norks Sports Bras Limited | Wholesale & retail | 2023 |
| Norpath (Management) Limited | Professional & scientific | 2012 |
| Norpath TLC Limited | Professional & scientific | 2008 |
| North 28 Ltd | Administrative & support | 2011 |
| North Britain Shooting & Events Ltd | Arts & recreation | 2023 |
| North Capital Securities Limited | Real estate | 1983 |
| North Crescent Ltd | Wholesale & retail | 2023 |
| North Detecting Events Limited | Arts & recreation | 2021 |
| North East Accounting & Tax Solutions Limited | Professional & scientific | 2022 |
| North East Ambulance Service Unified Solutions Limited | Wholesale & retail | 2017 |