| Somerset Skin Solutions Ltd | Other services | 2014 |
| Somerton Jewellery Ltd | Wholesale & retail | 2018 |
| Sophisticat Furniture Ltd | Manufacturing | 2018 |
| South West Farrier Ltd | Other services | 2018 |
| Southnest Ltd | Real estate | 2022 |
| Spa Simple Ltd | Manufacturing | 2023 |
| Spare Space Taxis Ltd | Transport & logistics | 2013 |
| Spec Fence and Lawn Ltd | Administrative & support | 2019 |
| Spheres Limited | Wholesale & retail | 2004 |
| Spitfire Gaming Limited | Other services | 2019 |
| Staffing Operational Solutions Limited | Health & social care | 2010 |
| Stand OUT Marketing Studio Limited | Professional & scientific | 2019 |
| Stand OUT Web Studio Ltd | Information & communication | 2025 |
| Stefy Criss Ltd | Health & social care | 2018 |
| Stemlake Limited | Real estate | 1999 |
| Steve Bartram Financial Services Limited | Financial services | 2012 |
| Stillwell Carpentry Limited | Construction | 2022 |
| Stillwell Property Maintenance and Management Ltd | Real estate | 2025 |
| Stirling (SW) Limited | Wholesale & retail | 2025 |
| Stockteam Limited | Wholesale & retail | 2026 |
| Strategic Rebel Ltd | Information & communication | 2017 |
| Street Barbers Ltd | Other services | 2023 |
| Street Foods Centre Ltd | Hospitality | 2025 |
| Street Football Club 2026 Limited | Arts & recreation | 2025 |
| Street Mini Market Ltd | Wholesale & retail | 2023 |
| Street Seafood UK Limited | Hospitality | 2026 |
| Summit Solutions (SW) Ltd | Construction | 2020 |
| Sunhaus Limited | Wholesale & retail | 2008 |
| Sunstor Limited | Wholesale & retail | 2017 |
| Supermix Sound & Lighting Ltd | Administrative & support | 2021 |
| Sushi House in Street Ltd | Hospitality | 2025 |
| SWC Engineering Limited | Manufacturing | 2008 |
| Syncedco Limited | Information & communication | 2026 |
| T5 Project Management Ltd | Information & communication | 2023 |
| Taking-The-Space CIC | Arts & recreation | 2022 |
| Talent Catalyst Ltd | Professional & scientific | 2011 |
| Talia Investment Holdings Ltd | Information & communication | 2025 |
| Tangled Roots Limited | Arts & recreation | 2019 |
| Tatra Holdings Ltd | Administrative & support | 2024 |
| TB9 Ltd | Hospitality | 2024 |
| TCT Drainage Limited | Construction | 2021 |
| TCT Groundworks Ltd | Construction | 2017 |
| Techosaurus Ltd | Information & communication | 2023 |
| Tecta Trading Ltd | Real estate | 2022 |
| Temple Electrical Ltd | Construction | 2022 |
| THE C Word Communications Ltd | Professional & scientific | 2020 |
| THE FLY Pack Company Ltd | Administrative & support | 2022 |
| THE Friendly Association of the Sharpham Collective | Other services | 2023 |
| THE Geeky Gamer Limited | Arts & recreation | 2022 |
| THE Godney Gathering Limited | Arts & recreation | 2016 |
| THE Health Unit Limited | Arts & recreation | 2024 |
| THE Little Wooden House Company Ltd | Construction | 2017 |
| THE Mighty Kitchen Limited | Wholesale & retail | 2024 |
| THE Purky Enclave Limited | Manufacturing | 2017 |
| THE South West School of Dance LLP | | 2017 |
| THE White Horse at Rogate Limited | Hospitality | 2026 |
| THE YA Group Ltd | Information & communication | 2019 |
| Thornhills Farm Limited | Other services | 2021 |
| Tiki Properties Limited | Real estate | 2006 |
| Timber Structures Limited | Construction | 2019 |
| Tizzy's Transport Ltd | Wholesale & retail | 2017 |
| TLD Medical Admin Services Ltd | Health & social care | 2023 |
| Toast Glastonbury Ltd | Hospitality | 2025 |
| Tolivy Ltd | Construction | 2023 |
| TOR AI Agency Ltd | Information & communication | 2026 |
| TOR Architectural Services Ltd | Professional & scientific | 2020 |
| TOR Printing Ltd | Manufacturing | 2019 |
| TOR Renewable Heating Solutions Ltd | Construction | 2021 |
| TOR View Self Storage Limited | Administrative & support | 2007 |
| TOR View Studios Ltd | Extraterritorial | 2019 |
| Total Clean Air Limited | Manufacturing | 2018 |
| Total Turnover Solutions Limited | Real estate | 2020 |
| TPM Tanker and Commercial Vehicle Repairs Limited | Wholesale & retail | 2025 |
| Traditional Homes Limited | Construction | 2017 |
| Tranquillity Hair Limited | Other services | 2014 |
| Trung Kien Nguyen Investment Limited | Real estate | 2026 |
| Trung Kien Nguyen Property Limited | Real estate | 2026 |
| Twkr Productions Ltd | Administrative & support | 2017 |
| TYRES2U Limited | Wholesale & retail | 2017 |
| U-Zit Bait Innovations Ltd | Manufacturing | 2023 |
| Ultimate Drylining Ltd | Construction | 2024 |
| Uniq Creative Limited | Information & communication | 2016 |
| Unthnkble Limited | Professional & scientific | 2019 |
| V C W M Limited | Real estate | 2014 |
| VAL Stones (Baker) Limited | Hospitality | 2017 |
| Valtone Paints and Welding Supplies Ltd | Wholesale & retail | 2025 |
| Vaper Online Ltd | Wholesale & retail | 2021 |
| Vapers Own Ltd | Wholesale & retail | 2021 |
| Vapersonline Ltd | Wholesale & retail | 2015 |
| Verismart Inventories Avon Limited | Real estate | 2016 |
| Vernoum Plumbing Heating & Renovation Ltd | Construction | 2019 |
| Vine Health Suites Ltd | Real estate | 2017 |
| Vitality Vortex Ltd | Arts & recreation | 2023 |
| VP & Co Property Ltd | Real estate | 2021 |
| Webb Retail Solutions Ltd | Professional & scientific | 2023 |
| Wells Parking Company Limited | Transport & logistics | 1992 |
| Wessex Testing Solutions Limited | Information & communication | 2015 |
| Wessex Websites Ltd | Information & communication | 2022 |
| Wessex Windows & Conservatories Ltd | Construction | 2017 |
| Winter and Simpson Retail Ltd | Construction | 2022 |