| Capall Livestock Ltd | Agriculture & fishing | 2021 |
| Capelloclo Ltd | Wholesale & retail | 2019 |
| Carron Place Limited | Administrative & support | 2011 |
| Casa Strathaven Ltd | Hospitality | 2023 |
| Castle Estate Agency Ltd | Real estate | 2024 |
| Castle Letting Agency Ltd | Households | 2018 |
| Castle Terrace 1831 Ltd | Professional & scientific | 2019 |
| Castle View (Strathaven) Limited | Hospitality | 2018 |
| Castleview Engineering Ltd | Construction | 2023 |
| CC Sportshorses Ltd | Agriculture & fishing | 2022 |
| CDL Couriers Ltd | Transport & logistics | 2020 |
| Centre for Customer Awareness Limited | Administrative & support | 2005 |
| CH Mobile Valeting Limited | Wholesale & retail | 2021 |
| Chapelton.As Ltd | Wholesale & retail | 2020 |
| Chert AI Limited | Information & communication | 2025 |
| Chestnut Interiors Ltd | Construction | 2016 |
| Chinese Strathaven Ltd | Hospitality | 2022 |
| CJN Corp Limited | Professional & scientific | 2022 |
| Clarendon Car and Classic Limited | Wholesale & retail | 2024 |
| Classic Scotland Limited | Administrative & support | 1996 |
| Classic Spares and Engineering Ltd | Wholesale & retail | 2014 |
| Clean Slate Home Services Limited | Administrative & support | 2026 |
| Clinical Projects Limited | Professional & scientific | 2021 |
| Cloughley Investments Ltd | Real estate | 2023 |
| Cloverhill Therapies Limited | Other services | 2011 |
| Clyde & Avondale Associates Ltd. | Professional & scientific | 2013 |
| Clyde Enterprises Ltd | Wholesale & retail | 2025 |
| CM Platinum Properties Ltd | Real estate | 2024 |
| Coffey's Property Ltd | Households | 2026 |
| Coldstream Commissioning Limited | Professional & scientific | 2020 |
| Communique Associates Limited | Professional & scientific | 1998 |
| Confident Business English Ltd | Professional & scientific | 2025 |
| Cooper Properties Strathaven Ltd | Real estate | 2021 |
| Coull Coaching Ltd | Education | 2017 |
| COX Construction Consultants Limited | Professional & scientific | 2006 |
| CP Detailing Ltd | Wholesale & retail | 2018 |
| Craigs of Strathaven Ltd | Wholesale & retail | 2018 |
| Crawford Scientific Holdings Limited | Professional & scientific | 2014 |
| Crct Ltd | Education | 2024 |
| Creative Strathaven CIC | Wholesale & retail | 2020 |
| Cruive Estate Agents Ltd | Real estate | 2023 |
| CS Aesthetics & Beauty Ltd | Other services | 2023 |
| CS Specialised Operational Solutions Ltd | Public administration | 2025 |
| Dahlia Music Ltd | Arts & recreation | 2019 |
| Dale Haskins Ltd. | Professional & scientific | 2013 |
| David Murdoch Services Limited | Manufacturing | 2016 |
| Davison Consulting Ltd | Professional & scientific | 2024 |
| Democritus Ltd | Professional & scientific | 2018 |
| Departure House Travel Limited | Administrative & support | 2025 |
| Desktop Messages Limited | Information & communication | 2006 |
| Diamond! Business Growth Ltd | Administrative & support | 2015 |
| Discount Kitchens and Bathrooms Ltd | Manufacturing | 2011 |
| DL Timber Buildings Ltd | Manufacturing | 2022 |
| DLT Properties (Glasgow) Ltd | Real estate | 2023 |
| Donmack Homes Ltd | Extraterritorial | 2023 |
| Dougie Gibbons Driving Ltd | Education | 2019 |
| DPB Tracing Services Limited | Administrative & support | 2011 |
| DR Paul Mccarthy Limited | Professional & scientific | 2015 |
| Dramatic Imagination LLP | | 2026 |
| Dundrummin Holdings Ltd | Financial services | 2021 |
| Dunlop GAS & Boiler Services Ltd | Construction | 2017 |
| Dunure Consulting Ltd | Professional & scientific | 2026 |
| DÚN AD Consultancy Ltd | Professional & scientific | 2026 |
| Eco Affordable Housing Limited | Construction | 2007 |
| ECOM24 Limited | Information & communication | 2004 |
| Edinburgh Golf Management Ltd | Arts & recreation | 2008 |
| Elegant Living Properties Ltd | Real estate | 2024 |
| Elitevg Ltd | Professional & scientific | 2023 |
| Ellbrae Stays Ltd | Hospitality | 2026 |
| Ellie's Investments Ltd | Real estate | 2024 |
| Envolv Ltd | Professional & scientific | 2025 |
| Epic Candy Limited | Wholesale & retail | 2024 |
| Equestar Limited | Arts & recreation | 2022 |
| Evolve Utilities Ltd | Construction | 2021 |
| Fairhaven Communications Limited | Information & communication | 2015 |
| Feather Arts Ltd | Arts & recreation | 2017 |
| Feature SET Ltd | Information & communication | 2020 |
| FLH Reporting Ltd | Health & social care | 2023 |
| Forrest Environmental Packaging Ltd | Administrative & support | 2025 |
| Four Ashes Logistics Ltd | Transport & logistics | 2023 |
| Fower Coffee Ltd | Manufacturing | 2020 |
| Freya's Glade Ltd | Hospitality | 2025 |
| Galloway Productions Ltd | Arts & recreation | 2019 |
| Gateway IT Services Ltd | Information & communication | 2024 |
| Gaukam Medical Services Ltd | Health & social care | 2026 |
| Gaun Yersel' Workshop Community Interest Company | Arts & recreation | 2025 |
| GB Agrispares Ltd | Wholesale & retail | 2018 |
| Gebbie & Wilson LLP | | 2017 |
| Geco Scotland Limited | Real estate | 2001 |
| General Badger Ltd | Wholesale & retail | 2025 |
| Geoff Mccluskey Ltd | Construction | 2017 |
| George Cheyne (Cycles) Limited | Real estate | 1947 |
| Geothermal Power Limited | Construction | 2015 |
| Gigiac Ltd | Other services | 2014 |
| Gimme Enterprises Limited | Wholesale & retail | 2024 |
| Glassford Quarry Company Limited (the) | | 1954 |
| Glenauld Breeders Ltd | Other services | 2023 |
| Glenavon Joinery & Construction Services Limited | Construction | 2011 |
| GLS Distribution Ltd | Wholesale & retail | 2024 |
| GM Leadership and Business Solutions Ltd | Professional & scientific | 2015 |