| Doodle Properties Private Limited | Real estate | 2023 |
| Dorsington Farms Limited | Agriculture & fishing | 1995 |
| Dorsington Manor Limited | Households | 1991 |
| Dose of Rose Ltd. | Wholesale & retail | 2015 |
| Double Colourless Limited | Information & communication | 2022 |
| Dovetail Joinery (Pershore) Ltd | Manufacturing | 2015 |
| DPA Agency Limited | Education | 2015 |
| DPB Consulting Ltd | Professional & scientific | 2024 |
| DR Craig Joyce Psychology Services Limited | Health & social care | 2021 |
| DR Hugo Limited | Health & social care | 2019 |
| DR Kerry West- Mindful Healing Ltd. | Health & social care | 2012 |
| DR Rosa Chillari Limited | Health & social care | 2021 |
| Dramdale Associates Ltd | Professional & scientific | 2016 |
| Dray Services Ltd | Manufacturing | 2023 |
| Draycotts Electrical Engineers Limited | Construction | 1957 |
| Driveclub Limited | Information & communication | 2023 |
| Driver 61 Limited | Manufacturing | 2016 |
| Drkb Locum Ltd | Health & social care | 2020 |
| Droneworx.Ai Ltd | Transport & logistics | 2024 |
| Drrrip Ltd | Manufacturing | 2016 |
| Drybones Ltd | Wholesale & retail | 2022 |
| Dryspell Contract Solutions Ltd | Construction | 2022 |
| Dryspell Irrigation Solutions Ltd | Wholesale & retail | 2024 |
| DS Distribution Ltd | Wholesale & retail | 2025 |
| Dscpls Music Ltd | Arts & recreation | 2026 |
| Dsrecoveryservice Ltd | Transport & logistics | 2023 |
| Dubbington Digital Ltd | Information & communication | 2023 |
| Ducks Crossing Properties Limited | Hospitality | 2024 |
| Dunamis Electrical Ltd | Construction | 2025 |
| Dundrannan Engineering Limited | Professional & scientific | 2025 |
| Durrani Estates Limited | Real estate | 2026 |
| DV8 Asset Management Limited | Wholesale & retail | 2022 |
| DV8 Works Limited | Administrative & support | 2016 |
| DWA Project Management Limited | Professional & scientific | 2017 |
| DY International Limited | Agriculture & fishing | 2025 |
| Dynaco Limited | Professional & scientific | 1985 |
| Dynamic Apps Ltd | Information & communication | 2018 |
| Dynamic Classics Limited | Wholesale & retail | 2023 |
| Dynamic Marketing Consultancy Limited | Professional & scientific | 2023 |
| Dynamics Direct Live Limited | Administrative & support | 2009 |
| Dyson Patchett Ltd | Professional & scientific | 2021 |
| E B & P Limited | Real estate | 2022 |
| E Holdings Ltd | Professional & scientific | 2015 |
| E Hutsby Properties Ltd | Real estate | 2025 |
| E&N Consultancy Group Ltd | Professional & scientific | 2012 |
| E.K.Partitions and Ceilings Ltd. | Construction | 1999 |
| Earlsdon Student Homes LLP | | 2015 |
| Earth Angel of Hope | Other services | 2020 |
| East and West Design Limited | Professional & scientific | 2017 |
| East Midlands Enterprise Foundation | Other services | 2025 |
| Eastern Ballet Productions Ltd | Arts & recreation | 2023 |
| Eastside Clothing Limited | Wholesale & retail | 2018 |
| Eastside Collective Ltd | Information & communication | 2016 |
| EAT Argentina Ltd | Wholesale & retail | 2022 |
| EC Build Design Ltd. | Professional & scientific | 2015 |
| Echlin Europe Limited | Professional & scientific | 1986 |
| ECL Properties (Sona) Limited | Real estate | 2017 |
| Eclipse Legal Capital Limited | Professional & scientific | 2024 |
| Eclipse Wealth Management Ltd | Financial services | 2019 |
| Eco Laser Stripping Ltd | Manufacturing | 2026 |
| Eco Waste Logistics Ltd | Water & waste | 2026 |
| Eco Work-Shop CIC | Health & social care | 2013 |
| Eco-Nomics (UK) Ltd | Professional & scientific | 2011 |
| Eco-Nomics Consulting Ltd | Professional & scientific | 2026 |
| Ecom Collab Club Limited | Professional & scientific | 2022 |
| Ecovista Solutions Limited | Information & communication | 2023 |
| ECS Staffing and Recruitment Ltd | Administrative & support | 2017 |
| Ecurie Esprit Limited | Extraterritorial | 2013 |
| ED Curtis Creative Limited | Arts & recreation | 2017 |
| ED Psych Midlands Ltd | Education | 2025 |
| Eden Habitats Ltd | Manufacturing | 2026 |
| Eden Learning Limited | Professional & scientific | 2025 |
| Edge & Associates Limited | Professional & scientific | 2017 |
| Edge 2020 Ltd | Professional & scientific | 2019 |
| Edge Recruitment Group Limited | Professional & scientific | 2019 |
| Edge Toxicology Consulting Limited | Professional & scientific | 2020 |
| Edgehill Shooting by Honesberie Limited | Arts & recreation | 2026 |
| Edity Ltd | Information & communication | 2024 |
| EDM Plus (UK) Ltd | Manufacturing | 2010 |
| Edstone Garden Services Ltd | Administrative & support | 2025 |
| EDT Exterior Cleaning Ltd | Administrative & support | 2025 |
| Eduaurora Group Limited | Financial services | 2025 |
| Edward Brain Holdings Limited | Real estate | 2026 |
| Edward Coyte Electrical Contractors Ltd | Construction | 2023 |
| EF Automotive Ltd | Wholesale & retail | 2023 |
| Efficient IS Limited | Information & communication | 2024 |
| Eiger Electrical Ltd | Construction | 2017 |
| Eitex Limited | Administrative & support | 2016 |
| Ekohouse Climate Systems Ltd | Wholesale & retail | 2025 |
| Electek Services Ltd | Manufacturing | 2024 |
| Electric Garden Stratford Ltd | Arts & recreation | 2023 |
| Electric Technics Ltd. | Wholesale & retail | 1998 |
| Electro Blue Limited | Financial services | 2024 |
| Elegance Nails Limited | Other services | 2016 |
| Elegant Spa & Beauty Limited | Other services | 2023 |
| Elektra Smart Energy Ltd | Construction | 2023 |
| Elite CAD Services Ltd. | Professional & scientific | 1998 |
| Elite Cake Designs Limited | Manufacturing | 2009 |
| Elite Floor Maintenance Ltd | Construction | 2015 |
| Elite Roofing & Construction Ltd | Construction | 2025 |