| DB Trading Limited | Agriculture & fishing | 2024 |
| DCM Haulage Ltd. | Transport & logistics | 2024 |
| Deerpark Trading Limited | Hospitality | 2006 |
| Degranno Holdings Limited | Financial services | 2026 |
| DEM Consultancy Ltd | Professional & scientific | 2023 |
| Denis Mcelroy Safety Services Ltd | Professional & scientific | 2026 |
| Dennett Outdoor Ltd | Wholesale & retail | 2004 |
| Dergalt Dairy Ltd | Agriculture & fishing | 2020 |
| Derton Media Ltd | Information & communication | 2021 |
| Devine & Co Limited | Other services | 2014 |
| Devine Agri Parts Ltd | Wholesale & retail | 2002 |
| Devine Cars Ltd | Wholesale & retail | 2021 |
| Devine Leisure Lodges Limited | Manufacturing | 2016 |
| Devine Scaffolding Services Ltd | Construction | 2019 |
| Devine Windfarms Limited | Energy | 2013 |
| DFE Contracts Limited | Construction | 2025 |
| DG Cars & 4X4 Ltd | Wholesale & retail | 2022 |
| DH Cold Store Solutions (UK) Limited | Energy | 2023 |
| DHS Scaffolding Limited | Construction | 2015 |
| Diadem Rose Ltd | Wholesale & retail | 2025 |
| Diamond Contract Services Ltd | Extraterritorial | 2012 |
| Digital Land Surveyors Limited | Professional & scientific | 2006 |
| Discount & EX Inventory Ltd | Wholesale & retail | 2002 |
| Divine Capital Ltd | Real estate | 2026 |
| DJH Construction Consultants Ltd | Construction | 2024 |
| DMC Autosales Ltd | Wholesale & retail | 2020 |
| DMG (Cogee) Limited | Real estate | 2002 |
| DNA Retail Ltd | Wholesale & retail | 2010 |
| Dogleg Golf Ltd | Arts & recreation | 2025 |
| Doherty Steel Fixing N.I. Limited | Construction | 2017 |
| Dolan Enterprises Limited | Real estate | 2010 |
| DON Neeson Groundworks Ltd | Construction | 2011 |
| Donaghey Fencing, Groundworks and Plant Hire Ltd | Administrative & support | 2025 |
| Donaire Advisory Ltd | Administrative & support | 2026 |
| Donemana Cultural Association Limited | Administrative & support | 2008 |
| Donna's Flowerbox Ltd | Wholesale & retail | 2011 |
| Donnas Flowerbox & Gifts Limited | Wholesale & retail | 2015 |
| Dooher Enterprises Limited | Real estate | 2025 |
| Doorat Farms Limited | Agriculture & fishing | 2022 |
| Dorans Costcutter Limited | Wholesale & retail | 2014 |
| DR Murray Aesthetics Ltd | Health & social care | 2022 |
| Dragon Brand Foods Limited | Manufacturing | 2005 |
| Dromore Plumbing & Heating Limited | Construction | 2015 |
| Drumbane Trading Stores Limited | Wholesale & retail | 2018 |
| Drumcraig Wind Limited | Energy | 2021 |
| Drumenny Transport Limited | Transport & logistics | 2017 |
| DS Fuels Limited | Wholesale & retail | 2021 |
| DTC Mentorship Limited | Education | 2024 |
| DTC Ventures Ltd | Wholesale & retail | 2022 |
| Duffy E-Commerce Limited | Wholesale & retail | 2024 |
| Dunamanagh and District Community Association Limited | Real estate | 1994 |
| Duncan Commercials Ltd | Wholesale & retail | 2024 |
| Duncan Motors (Melmount) Ltd | Wholesale & retail | 2022 |
| Dunlix Investments (UK) Limited | Professional & scientific | 2005 |
| Dunlix Investments IRE Ltd | Real estate | 2023 |
| E Gallen Foods UK Ltd | Manufacturing | 2023 |
| Easilink Community Transport | Transport & logistics | 2011 |
| Eatmor Foods Ltd | Extraterritorial | 2025 |
| Echo POS Consultancy Ltd | Other services | 2025 |
| Eco Wood Processing Limited | Manufacturing | 2023 |
| Ecotec(Ni) Limited | Manufacturing | 2022 |
| Eden Painting & Decorating Ltd | Construction | 2012 |
| Eggtek Limited | Wholesale & retail | 2020 |
| Ekme Limited | Real estate | 2016 |
| EL Chuchi Limited | Hospitality | 2026 |
| Elas Construction Ltd | Construction | 2020 |
| Elcaco Ltd | Information & communication | 2022 |
| Elite Plant Hire & Sales Limited | Construction | 2024 |
| Elite Plumbing Strabane Ltd | Construction | 2019 |
| Elite Properties & Maintenance Ltd | Real estate | 2025 |
| Elite Strength & Conditioning Ireland Limited | Education | 2019 |
| Elite Tyre Services (Ireland) Ltd | Wholesale & retail | 2010 |
| ELM Contracts Ltd | Construction | 2025 |
| Elysiam Limited | Professional & scientific | 2019 |
| EMD Contracts Ltd | Construction | 2026 |
| Emerald Autoparts Ltd | Wholesale & retail | 2015 |
| Emerald Lifestyle Ltd | Administrative & support | 2024 |
| Energy in Motion Personal & Online Coaching Ltd | Education | 2019 |
| Enhance Cosmetics by Lisa Peoples Ltd | Health & social care | 2021 |
| Enniskillen Pest Control Ltd | Administrative & support | 2025 |
| Esps Developments Limited | Construction | 2014 |
| Esps Holdco Limited | Construction | 2025 |
| Esps Propco Limited | Real estate | 2025 |
| ESS Contracts Limited | Construction | 2015 |
| ETF Contracts Ltd | Construction | 2025 |
| Eutopia Strategy Ltd | Professional & scientific | 2017 |
| Everybody Clap Productions Ltd | Arts & recreation | 2017 |
| Excel Tiling Limited | Construction | 2017 |
| Excel Trading Ireland Ltd | Wholesale & retail | 2022 |
| Fallup NI Ltd | Health & social care | 2018 |
| Fandango Events Limited | Professional & scientific | 2019 |
| Farrell Group Ltd | Financial services | 2019 |
| Farrell Holdings Ltd | Real estate | 2019 |
| Farrell Plant Ltd | Administrative & support | 2019 |
| Farrell Trailer Services Limited | Wholesale & retail | 2015 |
| Fatboyz Strabane Ltd | Hospitality | 2024 |
| FIR Trees Hotel Strabane Limited | Hospitality | 2000 |
| FL Propertyco Limited | Real estate | 2018 |
| Flakey Dove Ltd | Hospitality | 2019 |
| Flanagan Electrics Ltd | Construction | 2017 |