| Eco Maniax Ltd | Wholesale & retail | 2019 |
| Eco Smart Systems Limited | Manufacturing | 2019 |
| Eco-Eco Stationery Limited | Wholesale & retail | 2015 |
| Ecom Essence Ltd | Wholesale & retail | 2025 |
| Economical Living Solutions Ltd | Real estate | 2018 |
| ED Global Limited | Hospitality | 2026 |
| Eden Court (Lower Gornal) Management Company Limited | Households | 2022 |
| Edgebourn Building Contracts Limited | Construction | 1964 |
| Edgebourn Management Limited | Financial services | 2020 |
| Edges Solutions Ltd | Real estate | 2020 |
| Edmunds Estates Ltd | Real estate | 2022 |
| Edox Properties Limited | Real estate | 2016 |
| Education Tuition Ltd | Education | 2020 |
| Educational Psychology for Everyone Limited | Education | 2014 |
| Edwardsandwhitehouse Ltd | Wholesale & retail | 2022 |
| Edydav Ltd | Transport & logistics | 2021 |
| Eeles Ltd | Professional & scientific | 2021 |
| Effinity Associates Limited | Manufacturing | 2019 |
| Effinity Food Service Equipment Ltd | Hospitality | 2025 |
| Effinity Holdings Limited | Financial services | 2025 |
| EGL Engineering Limited | Professional & scientific | 2012 |
| EHQ Management Ltd | Real estate | 2023 |
| Ehsq Consultancy Ltd | Professional & scientific | 2024 |
| EJR Consultancy Ltd | Real estate | 2021 |
| EKA Heating Services Ltd | Construction | 2022 |
| Ekho Collective CIC | Administrative & support | 2022 |
| EL Pearson 26 Limited | Hospitality | 2026 |
| Elan AI Autovector Limited | Information & communication | 2026 |
| Electromac Ltd | Manufacturing | 2025 |
| Electronic Services and Distribution Limited | Real estate | 2013 |
| ELEV8 Marketing Studios Ltd | Professional & scientific | 2024 |
| Elevate Performance Academy Ltd | Arts & recreation | 2024 |
| Elevate Resin Ltd | Construction | 2026 |
| Elevated Leadership Ltd | Professional & scientific | 2024 |
| ELEVEN10CREATIVE Ltd | Professional & scientific | 2014 |
| Elia Horizon Investments Ltd | Real estate | 2026 |
| Eliga Consulting Limited | Information & communication | 2004 |
| Elite Access & Electrical Limited | Manufacturing | 2021 |
| Elite Cricket Coaching Limited | Arts & recreation | 2018 |
| Elite Dance and Acrobatics Ltd | Arts & recreation | 2021 |
| Elite Kitchens and Interiors Limited | Manufacturing | 2024 |
| Elite Landscaping Contractors Ltd | Construction | 2026 |
| Elite Repairs (West Midlands) Limited | Wholesale & retail | 2003 |
| Elite Transfers Ltd | Transport & logistics | 2022 |
| Elixir Smoothies Limited | Manufacturing | 2024 |
| Elixir Systems (UK) Ltd | Administrative & support | 2014 |
| Ella Property Investments Limited | Real estate | 2015 |
| Elleenor Ltd | Professional & scientific | 2023 |
| Ellie Preece Enterprises Ltd | Health & social care | 2011 |
| Elliot & Coleman Ltd | Administrative & support | 2023 |
| Ellis & Co Holdings Limited | Financial services | 2022 |
| Ellis Live Limited | Hospitality | 2016 |
| Ellissord Ltd | Real estate | 2024 |
| Elmbank Nursing Home Limited | Health & social care | 1994 |
| Elmfield Rudolf Steiner School Limited | Education | 1973 |
| Elpeeda Limited | Information & communication | 2023 |
| Elsamor Consulting Limited | Professional & scientific | 2026 |
| Embroidery Services Ltd | Wholesale & retail | 2021 |
| Emerald Stag Management Ltd | Professional & scientific | 2022 |
| Emily S B Limited | Hospitality | 2024 |
| EML Properties Limited | Construction | 2014 |
| Emma Baker Catering & Events Ltd | Hospitality | 2026 |
| Empire Fitness Gym Ltd | Arts & recreation | 2019 |
| Empire Sheds Limited | Manufacturing | 2011 |
| Emporium International Ltd | Wholesale & retail | 2022 |
| Empresa Enterprises Ltd | Real estate | 2023 |
| EMS Evesham Motor Sales Limited | Wholesale & retail | 2017 |
| EMS Evesham Motor Services Limited | Wholesale & retail | 2011 |
| Enaaye Healthcare Ltd | Health & social care | 2020 |
| Enablemint Limited | Information & communication | 2025 |
| Encompass Network Systems Ltd | Information & communication | 2021 |
| Endless Agency Ltd | Information & communication | 2022 |
| Energy Survey Performance Ltd | Other services | 2023 |
| English Crown Green Bowling Association Ltd | Extraterritorial | 2013 |
| English Crown Green Bowls Association Ltd | Extraterritorial | 2013 |
| Englishgcse.Co.Uk Limited | Education | 2024 |
| Enjoy Barbering Co Limited | Other services | 2018 |
| Enterprise Pipework Services Limited | Construction | 2006 |
| Enterprise Trading Ltd | Wholesale & retail | 2018 |
| Enville Ales Limited | Manufacturing | 1998 |
| Enville Brewery Limited | Extraterritorial | 2007 |
| Enville Consultancy Limited | Financial services | 2012 |
| Enville Manor Limited | Other services | 2004 |
| Enville Manor RTM Company Limited | Households | 2004 |
| Enville News Ltd | Wholesale & retail | 2020 |
| Enviro-Regs.Net Ltd | Professional & scientific | 2013 |
| Envirocare FMC Ltd | Construction | 2025 |
| Envirocare Maintenance Limited | Construction | 2002 |
| Envirosolutions - Support and Training Limited | Professional & scientific | 2011 |
| Envision Your Money Ltd | Information & communication | 2016 |
| Eotey Ltd | Financial services | 2015 |
| Epic Convenience Ltd | Wholesale & retail | 2026 |
| Equanimity CBT Limited | Health & social care | 2009 |
| Equip Health Limited | Education | 2017 |
| Equisec Limited | Administrative & support | 2024 |
| Erable Investments Ltd | Professional & scientific | 2024 |
| ERB Commerce Ltd | Wholesale & retail | 2025 |
| Erdington Administration Services Limited | Professional & scientific | 1988 |
| Ergo Films Ltd | Information & communication | 2016 |
| Eriditum Ltd | Professional & scientific | 2014 |