| DE Malsi Ltd | Real estate | 2015 |
| Dead Duck Support Ltd | Information & communication | 2019 |
| Deaf Dog Media Ltd | Arts & recreation | 2026 |
| Deafscope Link CIC | Other services | 2019 |
| Deafscope Services Ltd | Professional & scientific | 2026 |
| DEC Services UK Ltd | Administrative & support | 2009 |
| Declaro Support Limited | Information & communication | 2016 |
| Decor Central Limited | Wholesale & retail | 2025 |
| Defigo Consulting Limited | Information & communication | 2008 |
| DELILAH19 Ltd | Hospitality | 2019 |
| Deloffee Properties Limited | Hospitality | 2026 |
| Delphine Bevan LLP | | 2018 |
| Delphine Investments 5457HS Limited | Real estate | 2017 |
| Delphine Investments Limited | Real estate | 2017 |
| Delta Eccomerce Ltd | Wholesale & retail | 2025 |
| Delta Properties (Midlands) Limited | Real estate | 2012 |
| Denant Electrical Services Limited | Construction | 2012 |
| Denis N David Ltd | Transport & logistics | 2025 |
| Dennis Street Management Co. Limited | Households | 1983 |
| Dental Advisor Limited | Education | 2020 |
| Dental Professional Education Ltd. | Education | 2017 |
| Dentelle Therapy Ltd | Health & social care | 2022 |
| Derek M Carter Limited | Professional & scientific | 2021 |
| Dermacea Ltd | Wholesale & retail | 2007 |
| Dermar Management Services Limited | Households | 2019 |
| Deshmukh Homes Ltd | Real estate | 2025 |
| Design a Mortgage Ltd | Financial services | 2021 |
| Design IT Wise Limited | Information & communication | 2017 |
| Design to Build (2015) Limited | Professional & scientific | 2015 |
| Designed by SJC Ltd | Manufacturing | 2025 |
| Designer Paws Cosmetics Ltd | Wholesale & retail | 2023 |
| Detroit Donuts Ltd | Hospitality | 2017 |
| Device Services Ltd | Extraterritorial | 2025 |
| DEW Mortgages Limited | Professional & scientific | 2017 |
| DEW Projects Limited | Construction | 2013 |
| DGI Music Limited | Education | 2002 |
| DH Blinds Limited | Manufacturing | 2013 |
| Dhanvika Private Limited | Wholesale & retail | 2025 |
| Dhillon Food & Drinks Ltd | Hospitality | 2026 |
| DHV Accountancy Ltd | Professional & scientific | 2016 |
| Dial Estates Limited | Real estate | 2019 |
| Diamond Court Developments Limited | Real estate | 2010 |
| Diamond Creatan Limited | Other services | 2025 |
| Diamond Scissors (Stourbridge) Ltd | Other services | 2023 |
| Digester Ltd | Water & waste | 2024 |
| Digetl Ltd | Information & communication | 2021 |
| Digimux Ltd | Information & communication | 2020 |
| Digipulse Ltd | Professional & scientific | 2018 |
| Digital AGE Professionals Enterprise Limited | Wholesale & retail | 2022 |
| Digital Outdoor Media Limited | Professional & scientific | 2009 |
| Digital Productions Worldwide Limited | Manufacturing | 2013 |
| Digital Refineries Limited | Wholesale & retail | 2026 |
| Digital Sign Solutions Ltd | Information & communication | 2019 |
| Digital Supplies Ltd | Professional & scientific | 2005 |
| Digitalsprout Ltd | Information & communication | 2025 |
| Dignipets Cambridge Ltd | Professional & scientific | 2025 |
| Dignipets Holdings Limited | Financial services | 2021 |
| Dignipets Leicester Limited | Professional & scientific | 2023 |
| Dignipets Limited | Professional & scientific | 2018 |
| Dignipets Partners Limited | Professional & scientific | 2021 |
| Dignipets Stoke & Crewe Limited | Professional & scientific | 2024 |
| Dignipets Taunton Ltd | Professional & scientific | 2025 |
| Dignipets Telford Holdings Limited | Financial services | 2021 |
| Dignipets Telford Limited | Professional & scientific | 2021 |
| Dignipets Worcester Limited | Professional & scientific | 2024 |
| Dijstra Ltd | Information & communication | 2014 |
| Dingles Soil Ltd | Wholesale & retail | 2022 |
| Dinyard Ltd | Administrative & support | 2018 |
| Dion (Stourbridge) Limited | Hospitality | 2021 |
| Dippons Residents Association Limited (the) | Real estate | 1972 |
| Direct 2U.COM Limited | Extraterritorial | 2008 |
| Direct Ducting Limited | Professional & scientific | 2011 |
| DIRECT2PRINT Limited | Manufacturing | 2003 |
| Disconnected Bodies Ltd | Professional & scientific | 2020 |
| Discovery Plant and Tool Hire Limited | Administrative & support | 2022 |
| Diskin Drainage Solutions Ltd | Construction | 2008 |
| Distinction Consultancy Limited | Administrative & support | 2018 |
| Distribution Direct Ltd | Transport & logistics | 2007 |
| DJ Matty Entertainments Ltd | Arts & recreation | 2020 |
| DJB International Limited | Transport & logistics | 2024 |
| DJB Roofing Services Limited | Construction | 2025 |
| DJD Orthopaedics Ltd | Health & social care | 2019 |
| DJP Investments (UK) Limited | Professional & scientific | 2012 |
| DJW Property Investments Limited | Real estate | 2025 |
| DK Healthcare Limited | Health & social care | 2015 |
| DKO Services Ltd | Administrative & support | 2026 |
| DLB Foods Limited | Wholesale & retail | 2026 |
| Dlgpropertygroup Ltd | Real estate | 2025 |
| DLH Decorating Limited | Construction | 2014 |
| DLH Services Ltd | Professional & scientific | 2024 |
| DLW Europe Limited | Wholesale & retail | 2025 |
| DM Hale Limited | Financial services | 2024 |
| DM Media Services Limited | Information & communication | 2025 |
| DMA Couriers Ltd | Transport & logistics | 2025 |
| DMH Socials Ltd | Arts & recreation | 2024 |
| DMS Cafe Ltd | Hospitality | 2026 |
| DMW Interiors Limited | Construction | 2002 |
| DO OR DIE Adventures Ltd | Administrative & support | 2026 |
| Doctors Dose Ltd | Wholesale & retail | 2021 |
| Doddz Enterprises Ltd | Financial services | 2025 |