| Freshwinds | Health & social care | 2000 |
| Fried HUT ST1 Limited | Hospitality | 2019 |
| Friends Hardware & Tools Trading UK Ltd | Wholesale & retail | 2020 |
| Frift Ltd | Information & communication | 2022 |
| Fringe Hair (Stoke-On-Trent) Limited | Other services | 2013 |
| FRM Consultancy Ltd | Information & communication | 2015 |
| Frodoco Limited | Real estate | 2021 |
| Frog Solutions Limited | Manufacturing | 2010 |
| Frogsuit Limited | Wholesale & retail | 2016 |
| From Longton and Proud CIC | Arts & recreation | 2024 |
| From Longton and Proud New and Preloved Goods Ltd | Wholesale & retail | 2025 |
| From the Stork Bespoke Baby Ltd | Wholesale & retail | 2021 |
| Frontier Property Co. Ltd | Real estate | 2023 |
| Frontline Care Group Ltd | Administrative & support | 2022 |
| Frontline Healthcare Solutions Ltd | Administrative & support | 2018 |
| Frontline Recruits and Training Ltd | Administrative & support | 2021 |
| Frontlinedance | Arts & recreation | 2001 |
| Frost Consult Ltd | Professional & scientific | 2021 |
| Frost Maintenance & Property Ltd | Real estate | 2026 |
| Frost Properties (JLF) Ltd | Real estate | 2021 |
| Frostbound Ltd | Wholesale & retail | 2024 |
| FRS Property Developments Ltd. | Real estate | 2024 |
| Frumi Delicatese Ltd | Hospitality | 2024 |
| Fruntelata Aurel Ltd | Transport & logistics | 2020 |
| Frydays Golden FRY Ltd | Manufacturing | 2025 |
| FS Food Group Limited | Wholesale & retail | 2023 |
| FS Interiors Limited | Construction | 2018 |
| FSL Shkambi Diners Ltd | Hospitality | 2025 |
| FTG Care and Consultancy Services Limited | Administrative & support | 2022 |
| FTG Care Services Ltd | Administrative & support | 2025 |
| FTG Childcaring Services Ltd | Health & social care | 2024 |
| Fuego Handyman Ltd | Administrative & support | 2023 |
| Fuel Buyers UK Ltd | Transport & logistics | 2017 |
| Fuel Force Ltd | Other services | 2023 |
| Fufu's CUT (Hanley) Ltd | Other services | 2020 |
| Fuji Cars Ltd | Wholesale & retail | 2026 |
| Full Circle Care Ltd | Health & social care | 2008 |
| Full Circle Performance Ltd | Other services | 2019 |
| Full Circle Sports Limited | Professional & scientific | 2024 |
| Full Send People Limited | Professional & scientific | 2025 |
| Full Stretch Goalkeeping Ltd | Arts & recreation | 2022 |
| Full Throttle Finishes Limited | Wholesale & retail | 2024 |
| FUN Fair Ride Hire Limited | Administrative & support | 2015 |
| Funded Street Ltd | Financial services | 2026 |
| Funding PIE Ltd | Financial services | 2013 |
| Funeral Support Services (UK) Ltd | Other services | 2022 |
| Funky Chicken Meir Ltd | Hospitality | 2025 |
| Funky Fashions Ltd | Wholesale & retail | 2023 |
| Furlong Mills Ltd | Manufacturing | 1898 |
| Furnitechs Upholstery Ltd | Other services | 2016 |
| Furniture Solutions (SOT) Limited | Wholesale & retail | 2007 |
| Fused Sport Holdings Ltd | Financial services | 2025 |
| Fused Sports Limited | Wholesale & retail | 2017 |
| Fusible Systems Ltd | Wholesale & retail | 1996 |
| Fusion FC CIC | Arts & recreation | 2025 |
| Fusion Football Club Ltd | Arts & recreation | 2025 |
| Fusion UK Data Limited | Information & communication | 2004 |
| Future Accountancy Services Limited | Extraterritorial | 2024 |
| Future Aerospace Engineering Ltd. | Information & communication | 2014 |
| Future AI Ltd | Information & communication | 2021 |
| Future Classics Limited | Wholesale & retail | 2025 |
| Future Driveways and Patios Ltd | Construction | 2025 |
| Future Evolved Group Limited | Information & communication | 2019 |
| Future Financial Services Ltd | Real estate | 2025 |
| Future First Farming Ltd | Agriculture & fishing | 2026 |
| Future Homes Developments Limited | Construction | 2017 |
| Future Mapping Services Limited | Professional & scientific | 1999 |
| Future Play (Staffs) Ltd | Construction | 2023 |
| Future Tooling Limited | Wholesale & retail | 2009 |
| Futureflow Logistics Ltd | Transport & logistics | 2025 |
| Futurify Technologies Ltd | Administrative & support | 2024 |
| Futuristic Thinking Ltd | Administrative & support | 2023 |
| Futzone Ltd | Information & communication | 2025 |
| Fuzi FC Ltd | Manufacturing | 2025 |
| FVP 163 Ltd | Information & communication | 2016 |
| FWB Holdings Limited | Professional & scientific | 1996 |
| FWB Products Holdings Limited | Financial services | 2024 |
| FWB Properties Limited | Real estate | 1996 |
| FWB Property Holdings Limited | Financial services | 2024 |
| FWD Electric Limited | Construction | 2012 |
| FWM Medical Services Limited | Real estate | 2018 |
| Fynne AI Ltd | Information & communication | 2025 |
| FZ Solutions Ltd | Information & communication | 2015 |
| Félag Ltd | Professional & scientific | 2024 |
| G & D Lockett Investments Limited | Financial services | 2026 |
| G & S J Johnson (Engineering) Limited | Manufacturing | 2002 |
| G & SR Regeneration Ltd | Agriculture & fishing | 2018 |
| G & Turners Landscapes Limited | Administrative & support | 2025 |
| G Adelaja Limited | Administrative & support | 2018 |
| G and E Property Limited | Real estate | 2022 |
| G Bromley Plumbing & Heating Limited | Administrative & support | 2025 |
| G Cooke Ltd | Manufacturing | 2014 |
| G E D Environmental Services Ltd | Water & waste | 2016 |
| G H Gregory Ltd | Administrative & support | 2025 |
| G J Plumb and Build Limited | Construction | 2024 |
| G Jones Signalling Limited | Construction | 2017 |
| G K Developments (Staffs) Ltd | Construction | 2009 |
| G K GAS and Electrical Limited | Manufacturing | 2009 |
| G Plant (Midlands) Limited | Construction | 2012 |
| G Richardson Agri Limited | Wholesale & retail | 2019 |