| E1GHTY ON3 Limited | Real estate | 2025 |
| E2 Contract Lighting Ltd | Financial services | 2018 |
| EAG Food Limited | Hospitality | 2026 |
| Eagle Energy Ltd | Professional & scientific | 2022 |
| Eagle EYE Haulage Ltd | Transport & logistics | 2025 |
| Eagle Travel Express Ltd | Transport & logistics | 2022 |
| Eagleway Enterprise Limited | Hospitality | 2012 |
| Earley Sunshine Property Investments and Solutions Limited | Real estate | 2019 |
| Earlsdale Ltd | Agriculture & fishing | 2016 |
| Early Days (Staffordshire) Limited | Education | 2003 |
| Earth Systems Conservation Ltd | Agriculture & fishing | 2024 |
| Earth Trusted Ltd | Manufacturing | 2025 |
| Earthworx Recycling Limited | Water & waste | 2018 |
| EAS Partnership Ltd | Construction | 2024 |
| Easat Radar Systems Ltd | Manufacturing | 1986 |
| Easily Dunne Properties Ltd | Real estate | 2022 |
| East Midlands Fuels Limited | Wholesale & retail | 2014 |
| East Staffordshire Primary Care Partnership Limited | Other services | 2017 |
| East Town Tea Ltd | Wholesale & retail | 2026 |
| East West Residential Ltd | Real estate | 2021 |
| East West Travels (Stoke-On-Trent) Ltd. | Administrative & support | 2015 |
| EAST2EAST Claim Solutions Limited | Construction | 2024 |
| Easter EGG Ltd | Professional & scientific | 2016 |
| Eastern Delight Limited | Hospitality | 2018 |
| Eastern Delight Tunstall Ltd | Hospitality | 2025 |
| Eastern Express (ATR) Limited | Hospitality | 2021 |
| Eastern Express Estates Limited | Real estate | 2023 |
| Eastern Express Global Limited | Financial services | 2021 |
| Eastern Express Snacks Limited | Financial services | 2021 |
| Eastern Square Ltd | Wholesale & retail | 2024 |
| Easton Coffee Company Limited | Hospitality | 2019 |
| Eastview Group Limited | Construction | 2025 |
| Easy Clothes Limited | Wholesale & retail | 2019 |
| Easy Finance Car Company Limited | Professional & scientific | 2011 |
| Easy Goods Ltd | Wholesale & retail | 2013 |
| Easy Hire (Midlands) Ltd | Administrative & support | 2024 |
| Easy Mart Distribution Ltd | Wholesale & retail | 2025 |
| Easy Move (UK) Ltd | Real estate | 2014 |
| Easy Move Property Agent Ltd | Extraterritorial | 2020 |
| Easy Staff Solutions Limited | Administrative & support | 2025 |
| Easybus Limited | Transport & logistics | 2022 |
| Easydream Beds Limited | Extraterritorial | 1999 |
| Easyfone Limited | Extraterritorial | 2000 |
| Easylay Systems Limited | Construction | 2018 |
| Easylight Limited | Households | 1987 |
| Easylinks Holdings Limited | Professional & scientific | 2001 |
| Easyshop Emporium Ltd | Wholesale & retail | 2024 |
| EAT & Bite Restaurant and Takeaway Ltd | Hospitality | 2026 |
| EAT & Go Shelton Ltd | Hospitality | 2025 |
| EAT FLY and BE Happy Ltd | Transport & logistics | 2025 |
| EAT House 2026 Ltd | Hospitality | 2026 |
| EAT India Kompany Limited | Hospitality | 2020 |
| EAT Today Ltd | Hospitality | 2023 |
| Eatngo Limited | Hospitality | 2019 |
| Eaton Drafting Ltd | Administrative & support | 2007 |
| Eazy Dynamics Limited | Information & communication | 2024 |
| Ebay Seller Limited | Wholesale & retail | 2025 |
| Ebay Treasure Ltd Ltd | Wholesale & retail | 2025 |
| EBB & Flow Global Limited | Professional & scientific | 2021 |
| Eburaci Ltd | Real estate | 2024 |
| Ebuyzen Limited | Wholesale & retail | 2026 |
| Ecam Engineering Holdings Limited | Financial services | 2013 |
| Ecigswag Limited | Wholesale & retail | 2015 |
| Eclipse Access Solutions Limited | Construction | 2005 |
| Eclipse Database Consultants Limited | Information & communication | 1999 |
| Eclipse Packaging Limited | Administrative & support | 1996 |
| Ecnl Ltd | Professional & scientific | 2024 |
| Eco Fit Facilities Management Limited | Mining & quarrying | 2023 |
| Eco GAS Limited | Construction | 2019 |
| Eco Innovate Ltd | Manufacturing | 2022 |
| Eco Pet Parcel Ltd | Administrative & support | 2021 |
| Eco Revolver Ltd | Wholesale & retail | 2020 |
| Eco Support Care Ltd | Health & social care | 2026 |
| Eco Travel Private Hire Ltd | Transport & logistics | 2022 |
| Eco Window Home Solutions Limited | Wholesale & retail | 2014 |
| Eco-Fec Ltd | Professional & scientific | 2025 |
| Ecolineuk Ltd | Construction | 2019 |
| Ecomhas Commerce Ltd | Wholesale & retail | 2026 |
| Ecommify Solutions Ltd | Information & communication | 2024 |
| Ecomscape Limited | Wholesale & retail | 2024 |
| Ecostore (Staffordshire) Ltd | Administrative & support | 2017 |
| Ecotax Accounting Services Ltd | Professional & scientific | 2024 |
| Ecovan Solutions Limited | Wholesale & retail | 2023 |
| Ecowyse Ltd | Water & waste | 2025 |
| Ecrubox Digital Ltd | Professional & scientific | 2016 |
| Ecsu Ltd | Wholesale & retail | 2025 |
| Ectc Services Ltd | Construction | 2025 |
| ED Law Holdings Limited | Financial services | 2024 |
| Edainia Kennels Ltd | Wholesale & retail | 2021 |
| Edainia Property Ltd | Real estate | 2025 |
| Eden Childrens Care Ltd | Health & social care | 2024 |
| Eden Conquest Limited | Financial services | 2026 |
| Eden Enterprises Investment Ltd | Hospitality | 2022 |
| Eden Garden Rooms Ltd | Construction | 2012 |
| Eden Garden Studios Ltd | Construction | 2020 |
| Eden Hills Properties Limited | Real estate | 2022 |
| Eden Holistic Group Limited | Financial services | 2017 |
| Eden Holistic Pet Foods Limited | Manufacturing | 2013 |
| Eden House Living Limited | Health & social care | 2023 |
| Eden Leisure Birmingham Ltd | Hospitality | 2024 |