| Docwel Ltd | Real estate | 2023 |
| Dodd & Shone Limited | Real estate | 2013 |
| Dodsleigh Consulting Ltd | Professional & scientific | 2023 |
| DOE Perfumes Ltd | Wholesale & retail | 2025 |
| Doforno Limited | Hospitality | 2026 |
| Dog & Bone Properties Ltd | Real estate | 2000 |
| Dog & Bone Property Services Limited | Real estate | 2011 |
| Dog and Bone Projects Limited | Real estate | 2013 |
| Dog Transit Limited | Manufacturing | 2010 |
| Doherty Property Developments Limited | Real estate | 2022 |
| Dojo Property Ltd | Real estate | 2024 |
| Dolan Designs Limited | Professional & scientific | 2014 |
| Dolly's Giftware Limited | Manufacturing | 2025 |
| Domestic Appliances Corporate Limited | Construction | 2024 |
| Domestic Improvements 4 YOU Ltd | Construction | 2015 |
| Dominic & Andra Transport Ltd | Transport & logistics | 2019 |
| Dominic Logistic Ltd | Transport & logistics | 2019 |
| Dominion Deep Cleaning Limited | Administrative & support | 2025 |
| Dominion Plus Care Services Limited | Health & social care | 2021 |
| Domino N&S Ltd | Transport & logistics | 2017 |
| Dommy Controls Ltd | Manufacturing | 2024 |
| Dommy Scrab Ltd | Wholesale & retail | 2025 |
| Domus Property Services Ltd | Real estate | 2005 |
| Dona-Trans Ltd | Transport & logistics | 2017 |
| Donald Bradley Limited | Real estate | 1954 |
| Dong YIN Limited | Hospitality | 2025 |
| Donmac Solutions Group Ltd | Construction | 2017 |
| Donmini (UK) Limited | Manufacturing | 1995 |
| Donnerism Manchester Limited | Hospitality | 2023 |
| Donum DEI Management Ltd | Households | 2024 |
| Door Maintenance Specialists (Stoke on Trent) Limited | Manufacturing | 2004 |
| Door Maintenance Specialists Ltd | Manufacturing | 2020 |
| DOOR2DOOR Transport Ltd | Transport & logistics | 2023 |
| Doors Supreme Ltd | Construction | 2023 |
| Dorian Spencer Jones Limited | Construction | 2020 |
| Doriana Trans Ltd | Transport & logistics | 2019 |
| Dorick Investments Ltd | Professional & scientific | 2020 |
| Dorsete Maidstone Ltd | Construction | 2020 |
| Dorsett Holding Ltd | Financial services | 2024 |
| Dorsett Investments Ltd | Real estate | 2025 |
| Dost Holdings Ltd | Financial services | 2025 |
| DOT Dispatch Ltd | Transport & logistics | 2024 |
| DOT Garage Ltd | Wholesale & retail | 2024 |
| Dothings Ltd | Information & communication | 2018 |
| Double Apple Cafe Limited | Hospitality | 2026 |
| Double Crown Investments Ltd | Other services | 2025 |
| Double Deuce Levi Ltd | Hospitality | 2024 |
| Double N Trans Ltd | Transport & logistics | 2023 |
| Double Street Consulting Limited | Professional & scientific | 2017 |
| Double Top Properties Ltd | Real estate | 2025 |
| Double U Ventures Ltd | Real estate | 2025 |
| Dough Haven Bakery Ltd | Manufacturing | 2026 |
| Doval Gardens Management Company Limited | Hospitality | 2003 |
| Dove Valley Holdings Limited | Professional & scientific | 2006 |
| Dovercourt Motor Company Limited(The) | Extraterritorial | 1959 |
| Dovison Properties Limited | Real estate | 2017 |
| Down to Earth Designs Limited | Administrative & support | 2002 |
| Downes Equine Ltd | Agriculture & fishing | 2021 |
| Downtown Auto Repair Ltd | Wholesale & retail | 2025 |
| Doyen's Bar Restaurant Ltd. | Hospitality | 2024 |
| DP Elite Transport Ltd | Transport & logistics | 2025 |
| DP Hairdressing Limited | Other services | 2006 |
| DP Software and Services Ltd | Information & communication | 2006 |
| DPC Accountants Limited | Professional & scientific | 2007 |
| DPF Flash & Cleaning Ltd | Wholesale & retail | 2025 |
| DPG Engineering Developments Limited | Administrative & support | 2010 |
| Dpgdistributions Ltd | Wholesale & retail | 2023 |
| DPH Guillotine Services Limited | Manufacturing | 2008 |
| DPH Machine Services Limited | Manufacturing | 2016 |
| DPI Properties Limited | Real estate | 2015 |
| DPJ Norwood Holdings Ltd | Financial services | 2024 |
| DPM Stoke Ltd | Hospitality | 2025 |
| DPP Link Limited | Information & communication | 2025 |
| DPS Electrics Limited | Wholesale & retail | 1998 |
| Dpse Limited | Financial services | 2017 |
| DR Construction Staffordshire Ltd | Construction | 2020 |
| DR Data Limited | Information & communication | 2004 |
| DR Davies Medical Limited | Health & social care | 2022 |
| DR E Arshad Ltd | Health & social care | 2025 |
| DR Jayesh Shah Limited | Health & social care | 2011 |
| DR Raph Driving School Limited | Education | 2026 |
| DR Ryan Consultancy Limited | Health & social care | 2025 |
| DR Sukhera Limited | Health & social care | 2019 |
| DR Tiles Ltd | Wholesale & retail | 2025 |
| DR WJL Ltd | Health & social care | 2014 |
| Draco Rental Properties Limited | Real estate | 2020 |
| Dragcou Holdings Ltd | Extraterritorial | 2021 |
| Dragon Group Solutions Ltd | Administrative & support | 2021 |
| Dragon Triad Studios Limited | Information & communication | 2020 |
| Dragontail Dwellings Ltd | Construction | 2024 |
| Drakespur Limited | Manufacturing | 1996 |
| Draper & Co Properties Ltd | Real estate | 2020 |
| Draycott Nurseries and Landscape Sales Limited | Administrative & support | 2016 |
| Draycott Sports Centre Limited | Arts & recreation | 1972 |
| Drayton Group Limited | Wholesale & retail | 2001 |
| DRB Designs Group Ltd | Professional & scientific | 2022 |
| Drbs Developments Ltd | Professional & scientific | 2024 |
| Dream Build Construction Ltd | Construction | 2021 |
| Dream Fare Ltd | Administrative & support | 2024 |
| Dream Roomz Ltd | Other services | 2023 |