| Care Connect (North East) Ltd | Administrative & support | 2025 |
| Care Home Management Limited | Professional & scientific | 2004 |
| Care PAR Excellence Ltd | Health & social care | 2025 |
| Care Promotion Ltd | Health & social care | 2018 |
| Careerstone Ltd | Administrative & support | 2013 |
| Careys Credit Services Limited | Financial services | 2000 |
| Carmabrook Limited | Hospitality | 2001 |
| Carol Mitchell Financial Services Limited | Financial services | 2012 |
| Carpet Fresh North East Limited | Administrative & support | 2019 |
| Carroll & Meynell Transformers Limited | Manufacturing | 2005 |
| Carson Industrial Services Ltd | Construction | 2025 |
| Carter Body and Paint Ltd | Construction | 2025 |
| Carter Paint Ltd | Construction | 2017 |
| Carter Process Engineering Limited | Professional & scientific | 2007 |
| Carter Property Sourcing Limited | Real estate | 2015 |
| Carter Steel Holdings Limited | Financial services | 2024 |
| Carter Steel Limited | Wholesale & retail | 1970 |
| Casa Clothing Ltd | Wholesale & retail | 2019 |
| Casa Joinery Solutions Ltd | Construction | 2013 |
| Casayoga Ltd | Other services | 2019 |
| Casey Mechanical Services Ltd | Wholesale & retail | 2024 |
| Casey Waring Personal Training Ltd | Arts & recreation | 2025 |
| Cash OUT Entertainment Ltd | Arts & recreation | 2025 |
| Cask & Barrel Ltd | Hospitality | 2025 |
| Cass Building Services Ltd | Construction | 2025 |
| Cassanovas Ltd | Hospitality | 2024 |
| Castaway Chic Limited | Wholesale & retail | 2010 |
| Castle Haulage Ltd | Transport & logistics | 2023 |
| Castle Timber Buildings Ltd | Construction | 2026 |
| Castlegate Marine Club Limited | Other services | 2000 |
| Castlemartin HSE Services Limited | Professional & scientific | 2014 |
| Catalyst Stockton-On-Tees Limited | Other services | 2000 |
| Catering CI Supplies Ltd | Hospitality | 2026 |
| Catering for ALL Occasions Ltd | Hospitality | 2023 |
| Catford (Hartlepool) Limited | Professional & scientific | 1992 |
| Catherine Court (Burton-On-Trent) Management Company Limited | Real estate | 2010 |
| Catkind Group Ltd | Wholesale & retail | 2025 |
| Cayden Kian Limited | Manufacturing | 2024 |
| Caygill’S Deliveries Ltd | Transport & logistics | 2026 |
| CB Consultants Limited | Financial services | 2022 |
| CB Energy Solutions Limited | Construction | 2025 |
| CB Engineering Services Limited | Professional & scientific | 2007 |
| CB Telecoms Limited | Information & communication | 2018 |
| CBD by Better Day's Ltd | Other services | 2020 |
| CBD Sure Health Ltd | Other services | 2018 |
| Cbmpgroundworks Ltd | Construction | 2026 |
| CBS Partnership LLP | | 2025 |
| CCG Cables Ltd Ltd | Construction | 2025 |
| CCS GAS Specialist Ltd | Construction | 2020 |
| CD Engineering Holdings Limited | Financial services | 2020 |
| CD Engineering Services Limited | Construction | 2008 |
| CDE Fire Limited | Construction | 2026 |
| CDE Renewables Limited | Construction | 2026 |
| CDI High Access Limited | Construction | 2017 |
| CDL Leisure Ltd | Administrative & support | 2019 |
| CDR Holdings Limited | Financial services | 2022 |
| CDR M&E Services Ltd | Construction | 2021 |
| CDR Property Investments Limited | Real estate | 2022 |
| CDR Realisations 2024 Limited | Information & communication | 1998 |
| Ceatta Limited | Financial services | 2008 |
| Cedar Building Company Limited | Construction | 2000 |
| Cedar Northern Ltd | Construction | 2025 |
| Ceekay Global Ventures Limited | Wholesale & retail | 2025 |
| CEF Energy Solutions Ltd | Construction | 2018 |
| CEL Direct Ltd | Wholesale & retail | 2025 |
| Celestial Cart Ltd | Wholesale & retail | 2025 |
| Cell FIX NE Ltd | Information & communication | 2024 |
| Celtic Cleaning Services Ltd | Administrative & support | 2015 |
| Cendyn Limited | Information & communication | 2015 |
| Central Media Ltd | Other services | 2019 |
| Cephacharis Ltd | Manufacturing | 2025 |
| Ceratops Ltd | Information & communication | 2025 |
| Cerberus Games Ltd | Information & communication | 2021 |
| CF Accountancy Services Ltd | Professional & scientific | 2022 |
| CG Construction NE Ltd | Construction | 2022 |
| CGC Stockton Ltd | Hospitality | 2025 |
| CGD Plumbing & Heating Ltd | Construction | 2021 |
| CGR Property Group Limited | Hospitality | 2023 |
| CH Offshore Services Ltd | Manufacturing | 2021 |
| CH4 Sense (Services) Ltd | Professional & scientific | 2018 |
| CH4 Sense Limited | Other services | 2013 |
| Chahal Capital Portfolio Limited | Financial services | 2026 |
| Challeng (NE) Ltd | Professional & scientific | 2023 |
| Chamberlain & Company Limited | Information & communication | 2012 |
| Chameleon Cleaning Limited | Administrative & support | 2025 |
| Chamelia Ltd | Other services | 2024 |
| Chan Commercial Ltd | Wholesale & retail | 1988 |
| Chan Property Group Limited | Real estate | 2016 |
| Chandan Shouri Limited | Health & social care | 2024 |
| Chanprop Services Ltd | Administrative & support | 2018 |
| Chapeau Limited | Real estate | 2005 |
| Chapman Properties NE Ltd | Real estate | 2025 |
| Chapter 17 Linthorpe Ltd | Hospitality | 2024 |
| Chapter Four Properties Ltd | Real estate | 2025 |
| Chapters & Chai Limited | Wholesale & retail | 2025 |
| Charge Offshore Limited | Professional & scientific | 2024 |
| Charge on the Go Ltd | Professional & scientific | 2015 |
| Charis Resources Ltd | Wholesale & retail | 2024 |
| Charles Barn Recruitment Ltd | Administrative & support | 2025 |
| Charlie Gardner Communications Ltd | Information & communication | 2018 |