| DP Herts Constrution Limited | Construction | 2025 |
| DPH Properties Limited | Real estate | 2021 |
| DR Adamson Consulting Services Ltd | Health & social care | 2024 |
| DR Alexander Health & Aesthetics Ltd | Health & social care | 2024 |
| DR Armitage Ltd | Other services | 2020 |
| DR Investment Management Ltd | Administrative & support | 2011 |
| DR Kashif Jarral Limited | Health & social care | 2024 |
| DR Kaushliya Katechia Ltd | Health & social care | 2021 |
| DR R Daureeawoo Ltd | Health & social care | 2022 |
| DR Sriharsha Yatham Ltd | Health & social care | 2024 |
| DR Walters Consultancy Limited | Health & social care | 2025 |
| Dragapp.Com Limited | Information & communication | 2017 |
| Dragon Fire Audio Limited | Extraterritorial | 2018 |
| Drainbusters London Limited | Water & waste | 2004 |
| Draintech Solutions South Ltd | Other services | 2022 |
| Dream Automotive Ltd | Manufacturing | 2013 |
| Dream Colour Gifts Ltd | Extraterritorial | 2016 |
| Dream Super Tuning Limited | Manufacturing | 2019 |
| Dreamersclub Ltd | Manufacturing | 2016 |
| Dreamsands Travel Limited | Administrative & support | 2025 |
| Drew Seymour Limited | Information & communication | 2003 |
| Dripora Ltd | Wholesale & retail | 2026 |
| Drive in DIG in Limited | Hospitality | 2023 |
| Drive Logic Limited | Construction | 2016 |
| Driven by YOU Limited | Transport & logistics | 2004 |
| Driver Require Group Limited | Professional & scientific | 2014 |
| Driver Require Limited | Administrative & support | 2001 |
| Driveuk Ltd | Transport & logistics | 2024 |
| DRJ Home Improvements Limited | Construction | 2023 |
| DRL Consultancy Ltd | Health & social care | 2024 |
| DRM Build & Maintain Limited | Construction | 2025 |
| DRM Skills Limited | Other services | 2015 |
| Droid IT Systems Limited | Information & communication | 2010 |
| Drop Kerb Expert Limited | Construction | 2018 |
| Drowned Books Ltd | Arts & recreation | 2023 |
| DSA Plumbing + Heating Ltd | Construction | 2023 |
| DSJ Lettings Ltd | Real estate | 2017 |
| DSK Health Limited | Health & social care | 2019 |
| DSN Property Developments Limited | Construction | 2022 |
| DT Plumbing and Heating Services Ltd | Construction | 2018 |
| Dtba Property Group Ltd | Households | 2025 |
| DU Pont (U.K.) Industrial Limited | Manufacturing | 2000 |
| DU Pont (U.K.) Limited | Manufacturing | 2002 |
| DU Pont (U.K.) Trustees Limited | Extraterritorial | 1994 |
| Duality Ltd | Information & communication | 2022 |
| DUE North Agency Ltd | Information & communication | 2018 |
| DUE Process Ltd | Administrative & support | 2016 |
| Dulao Trans Ltd | Transport & logistics | 2014 |
| Duncan Clark (Insurance Brokers) Limited | Financial services | 1979 |
| Duncan Close Residents Association Limited | Households | 1989 |
| Duncan Plumbing Ltd | Construction | 2021 |
| Dungeon Works Ltd | Manufacturing | 2026 |
| Dunroamin Limited | Construction | 2023 |
| Duro Property Management Ltd | Administrative & support | 2025 |
| Dusque Limited | Manufacturing | 2006 |
| Dusties Cleaning Services Ltd | Administrative & support | 2024 |
| Dutchies Caribbean Kitchen Limited | Hospitality | 2025 |
| Dutty MIX Productions Ltd | Information & communication | 2023 |
| DW Consultancy Ltd | Professional & scientific | 2002 |
| DW GAS and Heating Limited | Administrative & support | 2025 |
| DW General Services Limited | Construction | 2022 |
| DW Racing Limited | Arts & recreation | 2021 |
| Dwilson Property Ltd | Real estate | 2019 |
| DWJ Consultants Ltd | Professional & scientific | 2013 |
| DWS Electrical Services Limited | Professional & scientific | 2018 |
| DX Telecoms Ltd | Information & communication | 2026 |
| Dyeverse Dollys Hairdressing Ltd | Other services | 2021 |
| Dynamic Climate Properties Ltd | Other services | 2022 |
| Dynamic Physiotherapy Limited | Education | 2009 |
| Dynamic Pro Ltd | Other services | 2022 |
| Dynamite Plates Ltd | Wholesale & retail | 2026 |
| Dyno Surveys Ltd | Professional & scientific | 2022 |
| DZ Building Ltd | Construction | 2019 |
| E a Windows & Doors Limited | Construction | 2023 |
| E Coulson Carpentry & Building Ltd | Construction | 2014 |
| E Coulson Property Limited | Other services | 2020 |
| E J Bartholomew Limited | Wholesale & retail | 2014 |
| E Marketing Support Ltd | Professional & scientific | 2023 |
| E P S Site Solutions Limited | Construction | 2011 |
| E-Niche Ltd | Wholesale & retail | 2015 |
| E-Pension Limited | Administrative & support | 2006 |
| Eagle Project Consulting Ltd | Administrative & support | 2022 |
| Eagle VR Ltd | Transport & logistics | 2019 |
| Eagles WINGS24 Ltd | Health & social care | 2023 |
| Ealing Broadway (Oxford Road) Management Company Limited | Real estate | 1984 |
| EAR Sock Ltd | Wholesale & retail | 2024 |
| Earl Style Limited | Other services | 2020 |
| Earldin Limited | Wholesale & retail | 1991 |
| Earth Haulage Limited | Construction | 2021 |
| East Sparks Ltd | Transport & logistics | 2021 |
| Eastern European Consultancy Ltd | Other services | 2000 |
| Eastgate Court (Dunstable) Management Company Limited | Households | 2006 |
| Easthill Faraday Limited | Construction | 2006 |
| Easthill Holdings Limited | Other services | 2016 |
| Easton Holdings Limited | Professional & scientific | 2019 |
| Easton IT Limited | Professional & scientific | 2022 |
| Easy Liners Limited | Manufacturing | 2011 |
| Easy to Learn Technology Ltd | Information & communication | 2023 |
| Easyrentuk SPV Ltd | Real estate | 2024 |
| Easytolearntech Limited | Information & communication | 2018 |