| Structurepreneur Ltd | Professional & scientific | 2025 |
| STS Electrical Limited | Construction | 2010 |
| STS Travel Service Ltd | Transport & logistics | 2026 |
| Stubbs Hall Farm Limited | Agriculture & fishing | 2021 |
| Student Media Solutions (SLP) Limited | Extraterritorial | 2013 |
| Student Media Solutions Limited | Information & communication | 2011 |
| Studio 2BR Limited | Professional & scientific | 1998 |
| Studio JPS Limited | Other services | 2015 |
| Studio Palermo Limited | Professional & scientific | 2016 |
| STUDLAND6 Limited | Real estate | 2020 |
| Style Occasions Limited | Professional & scientific | 2009 |
| Stylistic Trading Limited | Extraterritorial | 2016 |
| Styx and Stone Ltd | Wholesale & retail | 2024 |
| Subject Support Limited | Education | 2010 |
| Suda Star Construction Ltd | Construction | 2026 |
| Suda Star Ltd | Real estate | 2022 |
| Sudarshan Enterprises Ltd | Wholesale & retail | 2026 |
| Sudbury Property Development Limited | Construction | 2017 |
| Suffolk OWL Sanctuary | Arts & recreation | 2001 |
| Sujay Capital Ltd | Real estate | 2024 |
| Sujay Designs Ltd | Wholesale & retail | 2024 |
| Sujay Holdings Ltd | Financial services | 2024 |
| Sukaina Nutrition Ltd | Hospitality | 2020 |
| Sukh Shanti CIC | Health & social care | 2022 |
| Sultan's Food Limited | Hospitality | 2024 |
| Sumaria Consulting Ltd | Professional & scientific | 2021 |
| Sumi Beauty Limited | Other services | 2023 |
| Sumi Designs Ltd | Professional & scientific | 2022 |
| Summit International Education Limited | Administrative & support | 2017 |
| Sun City Auto Ltd | Wholesale & retail | 2023 |
| Sun Information Tech Ltd | Information & communication | 2025 |
| Sun Information Technology Ltd | Information & communication | 2021 |
| Suncare Consulting Ltd | Health & social care | 2024 |
| Suncoast Express Ltd | Transport & logistics | 2022 |
| Suncos Limited | Real estate | 2014 |
| Sundar Box Limited | Wholesale & retail | 2025 |
| Sunderland Group Limited | Financial services | 2019 |
| Sunflowerzero Limited | Administrative & support | 2025 |
| Sunil Foto's Ltd | Professional & scientific | 2026 |
| Sunkissed Tanning and Spa Ltd | Other services | 2024 |
| Sunninghill School Ltd | Education | 2023 |
| Sunny Enterprises Property Limited | Real estate | 2021 |
| Sunny Patel Coaching Limited | Other services | 2021 |
| Sunsan Properties Ltd | Real estate | 2014 |
| Sunterra Ltd | Mining & quarrying | 2019 |
| Super 4X4 Ltd | Wholesale & retail | 2020 |
| Super Express Store Ltd | Wholesale & retail | 2011 |
| Super Pixel Ltd | Information & communication | 2011 |
| Superabbey Limited | Construction | 1979 |
| Superior Stone Limited | Manufacturing | 1999 |
| Supply Chain and Procurement Consulting Ltd | Professional & scientific | 2009 |
| Supreme Plastering Services Ltd | Construction | 2015 |
| Surak Estates Ltd | Real estate | 2022 |
| Suresale Ltd | Real estate | 2016 |
| Surgi and Medic International Limited | Other services | 1996 |
| Surin Solutions Ltd | Information & communication | 2023 |
| Surjj Legal Limited | Professional & scientific | 2008 |
| Surjj Limited | Extraterritorial | 2008 |
| Surv Legal Limited | Professional & scientific | 2025 |
| SUS Power Consultants and Supply Ltd | Professional & scientific | 2022 |
| Susan Bosier Limited | Professional & scientific | 2003 |
| Sussex Technics Limited | Information & communication | 2024 |
| Sussex Tikvah | Extraterritorial | 1983 |
| Sussexgate Limited | Administrative & support | 1983 |
| Sustainable Business Hub Limited | Information & communication | 2022 |
| Sustained Enterprises Limited | Real estate | 2022 |
| Sutra LDN Ltd | Wholesale & retail | 2026 |
| Sutton Oak Properties Limited | Real estate | 2020 |
| Suvi Supply Ltd | Wholesale & retail | 2023 |
| SVB Consultants Limited | Information & communication | 2014 |
| SVB Estate Limited | Real estate | 2019 |
| SVL Store Ltd | Wholesale & retail | 2025 |
| SVS Investments Limited | Real estate | 1998 |
| Svsr Enterprise Limited | Hospitality | 2024 |
| Svtano Limited | Hospitality | 2018 |
| SW (FPA) Investments Limited | Administrative & support | 2020 |
| SW Advisors Limited | Professional & scientific | 2019 |
| SW4 Properties Limited | Real estate | 2007 |
| Swachh Enterprises Ltd | Information & communication | 2015 |
| Swades Estates Ltd | Professional & scientific | 2009 |
| Swaha Music Ltd | Arts & recreation | 2015 |
| Swan Care Group Ltd | Administrative & support | 2018 |
| Swan Lodge Barns Developments LLP | | 2006 |
| Swancap Services and Solutions Ltd | Information & communication | 2018 |
| Swanley Skylight LLP | | 2018 |
| Swanrose Property Limited | Construction | 2008 |
| Sweet Arrangements Ltd | Other services | 2011 |
| Sweet Resistance Chocolates Ltd | Manufacturing | 2026 |
| Swell Nell Ltd | Real estate | 2025 |
| Swift Motors Ltd | Wholesale & retail | 2022 |
| Swift Operations Limited | Construction | 2025 |
| Swift Property Auctions Ltd | Real estate | 2023 |
| Swiftdeeds Limited | Information & communication | 2025 |
| Swiftquill Limited | Administrative & support | 2004 |
| Switch Business Limited | Administrative & support | 2012 |
| Switch Business Supply Ltd | Wholesale & retail | 2019 |
| Swts Jewellery Limited | Administrative & support | 2008 |
| SXA. Ltd | Construction | 2018 |
| Syan Properties Ltd | Real estate | 2024 |
| Sybarite Jewellery UK Limited | Wholesale & retail | 2012 |