| DPS Pubs Ltd | Hospitality | 2025 |
| DR Abdullah Ltd | Health & social care | 2025 |
| DR Doshi Limited | Health & social care | 2020 |
| DR DW Holdings Limited | Health & social care | 2025 |
| DR LS Wellness Ltd | Health & social care | 2025 |
| DR Maryam Clinic Ltd | Health & social care | 2016 |
| DR Roberto Tirabosco Limited | Health & social care | 2017 |
| DR YAZ Limited | Health & social care | 2015 |
| Dragon FLY Ventura Capital Ltd | Wholesale & retail | 2016 |
| Dragonfly Scenics Limited | Information & communication | 2026 |
| Draught Design Ltd | Professional & scientific | 2017 |
| Drawbridge Investments Ltd | Households | 2014 |
| Draybridge Limited | Households | 1983 |
| Draycott House Management Company Limited | Real estate | 2005 |
| Drayton Towers Limited | Real estate | 2025 |
| Drazhi Prestige Ltd | Construction | 2025 |
| Dream Street Film Productions Limited | Information & communication | 2013 |
| Dream Team London Ltd | Construction | 2011 |
| Dreams at Key Limited | Construction | 2022 |
| Dreams Consultancy Limited | Information & communication | 2004 |
| DRG Medical Consulting Ltd | Health & social care | 2019 |
| DRG Properties Limited | Real estate | 2015 |
| Drive (Edgware) Ltd. | Construction | 2000 |
| Drive Construction Ltd. | Extraterritorial | 2011 |
| Drive Fusion Transport Ltd | Transport & logistics | 2024 |
| Drive Rail Services Ltd. | Extraterritorial | 2005 |
| Drivedale Developments Ltd. | Construction | 2007 |
| Drivify Ltd | Other services | 2024 |
| Drre Investments Ltd | Real estate | 2017 |
| Drrima Ltd | Health & social care | 2023 |
| Drylining Fixers Limited | Construction | 2017 |
| DS Compliance Consulting Services Ltd | Professional & scientific | 2021 |
| DS Design Build Ltd | Construction | 2017 |
| DS Innovation Limited | Professional & scientific | 2010 |
| DSC Superstore Ltd | Real estate | 2017 |
| DSD Construct Ltd | Construction | 2026 |
| DTR (Pinner) Ltd | Hospitality | 2018 |
| Dual Fuel Technology UK Limited | Professional & scientific | 2025 |
| Dualmatter Computing Limited | Information & communication | 2020 |
| Dublanc Studio Limited | Professional & scientific | 2001 |
| Duct Technologies Limited | Energy | 2023 |
| Duncan Professionals Limited | Administrative & support | 2011 |
| Dune Ventures Ltd | Administrative & support | 2022 |
| Duneane Asset Management Ltd | Real estate | 2019 |
| Dunton Cine Ltd | Manufacturing | 2023 |
| Dunton Green Restaurant Limited | Hospitality | 2022 |
| Dunwoody LLP | | 2006 |
| Dutch-Engels Consulting Ltd | Professional & scientific | 2011 |
| DV Security Limited | Information & communication | 2015 |
| Dv-Pharm Limited | Wholesale & retail | 2009 |
| Dvqt Limited | Other services | 2022 |
| DVX Motor Group Ltd | Wholesale & retail | 2022 |
| DW Finchley Road Limited | Health & social care | 2026 |
| DW Hill Group Limited | Health & social care | 2025 |
| Dwarkesh Bawa Ltd | Wholesale & retail | 2022 |
| DXG Privé Limited | Transport & logistics | 2025 |
| Dylre Limited | Health & social care | 2025 |
| Dynamic Friends Limited | Wholesale & retail | 2013 |
| Dynamic Marketing Services Limited | Other services | 2005 |
| Dynamite Audio Limited | Administrative & support | 2007 |
| Dynateck Limited | Wholesale & retail | 2001 |
| Dzimbadzamabwe Ltd | Hospitality | 2025 |
| E C Data Investments Ltd | Other services | 2013 |
| E Shima Transport Ltd | Transport & logistics | 2026 |
| E&K Associates Limited | Real estate | 2024 |
| E-Commerce Corporation LLP | | 2015 |
| E-Force Corporation LLP | | 2013 |
| E-Magine Blue Limited | Professional & scientific | 2013 |
| E.L. Treatments Limited | Other services | 2000 |
| E.V.H. Limited | Health & social care | 1990 |
| EA Nest Ltd | Real estate | 2019 |
| Eagle EYE QS Limited | Professional & scientific | 2023 |
| Eagle Star Aviation Limited | Professional & scientific | 2024 |
| Eagles Electrical Contractors Ltd | Construction | 2023 |
| EAK Capital Ventures Ltd | Real estate | 2024 |
| Earlyworld Estates Limited | Financial services | 1987 |
| Earlyworld Property Holdings Limited | Professional & scientific | 2008 |
| Earndrive 1 Limited | Extraterritorial | 2003 |
| Earndrive 2 Limited | Extraterritorial | 2003 |
| Earndrive 3 Limited | Extraterritorial | 2003 |
| Earndrive Limited | Real estate | 2003 |
| East Heath Holdings Ltd | Financial services | 2025 |
| East London Shoes Limited | Real estate | 1992 |
| Eastern Esplanade (Cliftonville) Management Company Limited | Professional & scientific | 1988 |
| Eastlane (UK) LLP | | 2011 |
| Eastside Investments Limited | Real estate | 2004 |
| Eastway Estates Limited | Real estate | 1998 |
| Easy Take Away Limited | Transport & logistics | 2018 |
| Easyfix Rubber (UK) Limited | Manufacturing | 2019 |
| Easylane Rentals Limited | Administrative & support | 2024 |
| Easymart Limited | Real estate | 2000 |
| Eatco Foods Limited | Wholesale & retail | 2021 |
| EBA Estates Ltd | Real estate | 2022 |
| Ebberns Holdings Limited | Professional & scientific | 2005 |
| Ebberns Limited | Wholesale & retail | 1985 |
| Ebnz Limited | Professional & scientific | 2004 |
| EC Francis Services Limited | Construction | 2014 |
| Eccentric Professionals Ltd | Wholesale & retail | 2011 |
| ECG Catering Services Ltd | Hospitality | 2019 |
| ECG Contract Services Limited | Construction | 2019 |