| Toxicdragon Ltd | Information & communication | 2025 |
| Tracey Hamilton Hairdressing Ltd | Other services | 2002 |
| Trade Car Centre Limited | Administrative & support | 2014 |
| Trade Cutting Formes Limited | Manufacturing | 1988 |
| Triple JW Limited | Real estate | 2024 |
| Triple Threat Consultancy Ltd | Administrative & support | 2016 |
| TRS Auto Centre Ltd | Wholesale & retail | 2024 |
| TS Johnson Vauxhall Spares Limited | Wholesale & retail | 2009 |
| Tsec Limited | Manufacturing | 2005 |
| Tt&St Stores Ltd | Wholesale & retail | 2025 |
| TTT Construction Limited | Construction | 2011 |
| Turnmill Engineering Limited | Professional & scientific | 2017 |
| Tuvec Ltd | Health & social care | 2016 |
| TW Solutions Group Limited | Financial services | 2023 |
| Tweed Civil Engineering and Construction Ltd | Construction | 2018 |
| Twin Regency Limited | Real estate | 2020 |
| Tyne Sentinel Ltd | Administrative & support | 2026 |
| Tyne Vale Pharm Ltd | Wholesale & retail | 2025 |
| Tyne Valley Land & Development Ltd | Professional & scientific | 2024 |
| UK American Football Live Ltd | Arts & recreation | 2018 |
| UK FM Traders Limited | Financial services | 2012 |
| UK Pizza & Kebab (NE) Ltd | Hospitality | 2018 |
| UK Pizza Stanley Ltd | Hospitality | 2026 |
| Ukcex Ltd | Wholesale & retail | 2017 |
| Ultimate Bounce Ltd | Arts & recreation | 2025 |
| UMH Linx Ltd | Construction | 2025 |
| Union JAB CIC | Health & social care | 2022 |
| Unique Group International Ltd | Arts & recreation | 2018 |
| United Industrial Limited | Real estate | 2001 |
| Unitylogic Ltd | Information & communication | 2024 |
| Urban East Ltd | Real estate | 2019 |
| Urpeth Farms Limited | Agriculture & fishing | 1960 |
| Valley View Cafe Ltd | Hospitality | 2025 |
| Value Heating Services UK Ltd | Construction | 2021 |
| Vane Tempest Locomotive Group Limited | Manufacturing | 2025 |
| Vconnect Group Domiciliary Care Services Limited | Health & social care | 2025 |
| Vconnect Group Limited | Administrative & support | 2025 |
| Velvet Rose Floristry Limited | Wholesale & retail | 2025 |
| Veridian Estates Limited | Real estate | 2026 |
| Versatile Construction Ltd | Construction | 2022 |
| Vertex Media UK Limited | Professional & scientific | 2010 |
| Victory Business Services Ltd | Real estate | 2024 |
| View Windows Limited | Construction | 1997 |
| VIR Fish and Chips Ltd | Hospitality | 2024 |
| Vrhk Co. Ltd | Real estate | 2020 |
| W B Tyne & Wear Limited | Education | 2008 |
| W F Leisure UK Limited | Arts & recreation | 2007 |
| Wagtail Equine Therapy CIC | Health & social care | 2025 |
| Walk on UK Property Limited | Professional & scientific | 2024 |
| Wan's Property Limited | Real estate | 2020 |
| Waste Brothers Ltd | Water & waste | 2021 |
| Watson's Solutions Group Ltd | Transport & logistics | 2023 |
| Wayne Ellis Holdings Limited | Financial services | 2025 |
| Wealthy Homes Limited | Real estate | 2020 |
| Weathertight Developments Limited | Financial services | 2025 |
| West END Prep Limited | Arts & recreation | 2020 |
| West Pizza Stanley Ltd | Hospitality | 2024 |
| Westport Hospitality Ltd | Hospitality | 2025 |
| Weymouth British Vape Company Ltd | Wholesale & retail | 2024 |
| Whickham Chiropractic Clinic Limited | Health & social care | 2004 |
| White-Le-Head Cottages Ltd | Hospitality | 2019 |
| Whitfield and Lindsay Limited | Wholesale & retail | 1972 |
| WHY AI Ltd | Professional & scientific | 2026 |
| WHY Ltd | Wholesale & retail | 2004 |
| Wilgrow Nursery Limited | Wholesale & retail | 2024 |
| Wilson Developments NE Ltd | Extraterritorial | 2024 |
| Winegum & Winegut Limited | Real estate | 2021 |
| Winson Consultancy Limited | Professional & scientific | 2020 |
| Wired Systems Ltd | Information & communication | 2024 |
| Wolf Solutions Limited | Administrative & support | 2025 |
| Womani Limited | Manufacturing | 2026 |
| Woodlea Property Management Limited | Households | 2018 |
| Wreckreation Ltd | Wholesale & retail | 2017 |
| Writesound Creative Ltd | Professional & scientific | 2019 |
| WTR Utilities Ltd | Professional & scientific | 2026 |
| Wynyard Health Ltd | Health & social care | 2023 |
| Wynyard Health Provider Ltd | Health & social care | 2025 |
| Wyvern Installations Limited | Arts & recreation | 2026 |
| XL Escapes Ltd | Households | 2024 |
| Xperior Limited | Professional & scientific | 2017 |
| Yalini Convenience Store Ltd | Wholesale & retail | 2026 |
| Yellow Timber Limited | Real estate | 2020 |
| Yellow-Red Ltd | Professional & scientific | 2025 |
| Yonin + G Limited | Real estate | 2020 |
| York Charms Limited | Wholesale & retail | 2023 |
| Your Roofing Solutions Limited | Construction | 2015 |
| Your Startup Coach Ltd | Professional & scientific | 2025 |
| Yoyo Pizza Ltd | Hospitality | 2020 |
| Yoyo Solutions Limited | Information & communication | 2022 |
| YU & LEE Props Limited | Real estate | 2020 |
| ZAC Graham Brickworks Ltd | Construction | 2026 |
| Zand Newcastle Ltd | Hospitality | 2026 |
| Zarcade Limited | Arts & recreation | 2019 |
| Zentro Profinish Ltd | Construction | 2026 |
| ZIT Care Ltd | Health & social care | 2025 |
| Zplus Company Limited | Real estate | 2020 |