| M Wakefield Property Limited | Real estate | 2025 |
| M&K Medical Partners Limited | Health & social care | 2026 |
| M&Q Food Limited | Hospitality | 2023 |
| M. J. Delaney Holdings Limited | Real estate | 1995 |
| M.G Insurance Consultants Limited | Financial services | 1997 |
| M.J. Delaney & Co (Developments) Limited | Real estate | 1985 |
| M.J. Delaney & Co. Limited | Construction | 1982 |
| M1 Money Limited | Financial services | 2021 |
| M24 Engineering Solutions Ltd | Professional & scientific | 2024 |
| M35 Rail Limited | Manufacturing | 2020 |
| M51 Operations Limited | Hospitality | 2025 |
| MA Psychiatrist Limited | Health & social care | 2024 |
| MAC Trading Europe Limited | Administrative & support | 2005 |
| Mactapes Limited | Manufacturing | 2004 |
| Magoo Media Limited | Professional & scientific | 2017 |
| Magpies Nest Limited | Wholesale & retail | 2017 |
| Mailbox Limited | Manufacturing | 1986 |
| Mainframe North Limited | Administrative & support | 2008 |
| Malwa Brother Ltd | Transport & logistics | 2025 |
| Manchester Best Choice Ltd | Wholesale & retail | 2018 |
| Manchester Cultural Foundation Ltd | Health & social care | 2024 |
| Manchester Engineering Ltd | Manufacturing | 2023 |
| Manchester Logistics Solutions Ltd | Transport & logistics | 2020 |
| Manchester Precision Engineering Limited | Professional & scientific | 1993 |
| Manchester Property Repairs Ltd | Households | 2025 |
| Manchester Video Limited | Professional & scientific | 2007 |
| Manimousse Ltd | Wholesale & retail | 2025 |
| Manlec Electrical (Manchester) Limited | Construction | 1977 |
| Manor Self Storage (NW) Ltd | Real estate | 2025 |
| Marco Boldini Notary Limited | Professional & scientific | 2023 |
| Mariner Jack Ltd | Manufacturing | 2016 |
| Mark Smith Pro Golf Limited | Arts & recreation | 2010 |
| Marsland Commissioning Services Limited | Construction | 2024 |
| Maru Projects Limited | Construction | 2025 |
| Mason Family Properties Limited | Real estate | 2016 |
| Masterclass Soccer Limited | Education | 2024 |
| Matchmaker Properties Ltd | Real estate | 2026 |
| Matt Cowley Racing Ltd | Arts & recreation | 2019 |
| Matthew James Insurance Brokers Ltd | Financial services | 2019 |
| Mattify Ltd | Wholesale & retail | 2024 |
| MB Landscape & Garden Services Limited | Construction | 2022 |
| MB Landscape Services (North West) Limited | Construction | 2014 |
| MCA Property Management Limited | Real estate | 2016 |
| MCD Construction Consultancy Limited | Administrative & support | 2010 |
| Mcgiffen Masonry Limited | Construction | 2016 |
| Mcgrail Holdings Limited | Real estate | 2019 |
| Mckenna Gordon Limited | Education | 2015 |
| Mcmanus Properties Limited | Real estate | 2025 |
| MCR Dance Ltd | Arts & recreation | 2022 |
| MCR Events & Catering Ltd | Hospitality | 2023 |
| Mcveigh Highland Limited | Financial services | 2020 |
| Mcveigh Offsite Limited | Construction | 2012 |
| Mcveigh Projects Limited | Construction | 2012 |
| MD Audio & AV Ltd | Wholesale & retail | 2014 |
| Medipath Ltd | Education | 2024 |
| Medstor Limited | Administrative & support | 1983 |
| Melandra Castle Limited | Construction | 2018 |
| Memories Funeral Service Limited | Other services | 2018 |
| Memories Limousines Limited | Transport & logistics | 2020 |
| Memories Support Services Limited | Other services | 2023 |
| MEP Revit Limited | Professional & scientific | 2024 |
| MET 24 Limited | Manufacturing | 2024 |
| Mexdel Ltd | Transport & logistics | 2024 |
| MFP Professional Ltd | Health & social care | 2019 |
| Mgic Holdings Limited | Real estate | 2011 |
| Mi:Q-Skin Ltd | Wholesale & retail | 2021 |
| Michele Tighe-Mistry Solutions Limited | Professional & scientific | 2022 |
| Mickeys Local Ltd | Wholesale & retail | 2023 |
| MID Atlantic Growth Consultants Ltd. | Wholesale & retail | 2012 |
| Mikes Landscaping Services Ltd | Administrative & support | 2023 |
| Milcon Manchester Limited | Wholesale & retail | 2015 |
| Milkomilk-O-Licious Ltd | Extraterritorial | 2017 |
| Millwood Wellness Centre CIC | Other services | 2025 |
| Milton Rose Consulting Ltd | Professional & scientific | 2019 |
| Mimosa Fashion Limited | Wholesale & retail | 2019 |
| Mind First Care Solutions Ltd | Health & social care | 2025 |
| Miru Living Limited | Hospitality | 2025 |
| Misurati Limited | Health & social care | 2023 |
| MJ Pharmaceuticals Ltd | Health & social care | 2021 |
| MJS Consultants Limited | Construction | 2021 |
| MK Moss Properties Ltd | Construction | 2026 |
| MK Planning Ltd | Construction | 2016 |
| Mlxv Consulting Ltd | Professional & scientific | 2024 |
| Mlxv Properties Ltd | Real estate | 2024 |
| Mochan Developments Limited | Construction | 2016 |
| Moda IT Services (UK) Limited | Information & communication | 2021 |
| Monarch Mortgage Solutions Ltd | Financial services | 2018 |
| Monetra Ltd | Wholesale & retail | 2024 |
| Monk Bretton Estates Ltd | Construction | 2020 |
| Montgomery Joshua Limited | Administrative & support | 2016 |
| Moody Motors Ltd | Wholesale & retail | 2019 |
| Moonchild Enterprise Ltd | Construction | 2020 |
| Moorland Homes North West Ltd | Construction | 2021 |
| Moorlands Human Capital Ltd | Administrative & support | 2011 |
| Morley Waste Traders Limited | Wholesale & retail | 1959 |
| Mortins Services Ltd | Administrative & support | 2025 |
| Mossley Developments Ltd | Real estate | 2025 |
| Mossley Juniors F.C. Limited | Arts & recreation | 2020 |
| Mossley Plumbing Limited | Construction | 2012 |
| Mottram Commercial Properties Limited | Construction | 2017 |