| R T Macfarlane Ltd | Real estate | 2018 |
| R&A Brothers Ltd | Real estate | 2018 |
| R&D Developments (Staffordshire) Ltd | Real estate | 2024 |
| R&J Studios Ltd | Information & communication | 2024 |
| R&R Render Solutions Ltd | Construction | 2026 |
| R.A.P. Agricultural and Garden Services Limited | Other services | 2007 |
| R.D. Hunt Limited | Construction | 1975 |
| R.H.S Carpentry Services Ltd | Construction | 2019 |
| R.H.S Property Development Ltd | Real estate | 2020 |
| R.J.Young Properties(Stafford)Limited | Real estate | 1962 |
| R.L. Davies Surfacing Limited | Construction | 1997 |
| R2 (UK) Limited | Professional & scientific | 1998 |
| R4 Consulting Ltd | Professional & scientific | 2021 |
| RA Edwards Group Limited | Financial services | 2017 |
| Ra-Networks Limited | Information & communication | 2002 |
| RAB Auto Services Limited | Wholesale & retail | 2024 |
| Rackd Fitness Limited | Information & communication | 2026 |
| Radcoda Limited | Education | 2026 |
| Radford Rise Maintenance Limited | Administrative & support | 2015 |
| Radio Waves (Penkridge) Limited | Information & communication | 2014 |
| Radmore Contracts Ltd | Other services | 2004 |
| Radtec Limited | Professional & scientific | 2000 |
| RAE ANN Homes Limited | Real estate | 2024 |
| RAF Enterprise Limited | Hospitality | 2013 |
| Rafat International Co., Ltd | Wholesale & retail | 2024 |
| RAH Psychiatry & Healthcare Limited | Health & social care | 2016 |
| Raheem’S Concierge Ltd | Administrative & support | 2026 |
| Rail Vehicle Design Limited | Professional & scientific | 2026 |
| Railability Limited | Manufacturing | 1998 |
| Railway & Tramway Engineering Ltd | Professional & scientific | 2017 |
| Railway (Stafford) Ltd | Hospitality | 2023 |
| Rainbow Estate Management Limited | Real estate | 2024 |
| Rainbow Financial Limited | Financial services | 2019 |
| Rainbow Holdings Staffordshire Limited | Financial services | 2026 |
| Rainbow Property Management Staffordshire Limited | Real estate | 2026 |
| Rajntaj Limited | Real estate | 2025 |
| Raleigh 2016 Limited | Real estate | 2002 |
| Ralphs Studio Ltd | Professional & scientific | 2021 |
| Ramhair Lichfield Ltd | Other services | 2024 |
| Ramsey Bars Ltd | Hospitality | 2022 |
| Ramu Impex Global Ltd | Wholesale & retail | 2025 |
| Ranton Trout Fishery Limited | Agriculture & fishing | 2023 |
| Rapid Merchandising Limited | Wholesale & retail | 2013 |
| Rapid Response Roofing Ltd | Construction | 2021 |
| Rapid Web Services Limited | Information & communication | 2018 |
| Rapidracerproducts Limited | Manufacturing | 2007 |
| Rare Moves Limited | Transport & logistics | 2021 |
| Rarechart Limited | Real estate | 1987 |
| Rasvinder Singh Sudan LLP | | 2026 |
| Rattray Milne Ltd | Hospitality | 2013 |
| Rattylogistics Limited | Other services | 2020 |
| RAW Recruitment (East Midlands) Limited | Administrative & support | 2026 |
| RAY PAY Technology Ltd | Wholesale & retail | 2025 |
| Rayan Halal Store Ltd | Wholesale & retail | 2026 |
| Raybert Ltd | Hospitality | 2022 |
| Raying Technology Co., Ltd | Manufacturing | 2022 |
| Rayshine Global Academy Limited | Administrative & support | 2024 |
| RB & Sons Plumbing & Heating Ltd | Construction | 2024 |
| RB Accounts Limited | Professional & scientific | 2006 |
| Rbolesta Ltd | Transport & logistics | 2021 |
| RCR Limited | Extraterritorial | 2002 |
| RD Lyme Limited | Wholesale & retail | 2017 |
| RDA2023TRADING Limited | Education | 2023 |
| Rdlsharpe Limited | Construction | 2026 |
| Rdsmidlands Ltd | Transport & logistics | 2024 |
| RDW Business and Accountancy Services Ltd | Professional & scientific | 2025 |
| Re-Solv Charity | Health & social care | 1984 |
| Reade Property Limited | Real estate | 2020 |
| Reb-Tek UK Limited | Real estate | 2017 |
| Rebel Records and Toys Limited | Wholesale & retail | 2021 |
| Rebenx Engineering & Supplies Ltd | Extraterritorial | 2015 |
| Recovapack Ltd | Health & social care | 2026 |
| Recreations by Centenary Lounge Limited | Manufacturing | 2010 |
| Recruit DNA Ltd | Administrative & support | 2026 |
| Red Bear Retails Limited | Wholesale & retail | 2026 |
| Red Box Web Design Limited | Information & communication | 2014 |
| Red Button Films Limited | Information & communication | 2005 |
| Red Camels Trding Limited | Wholesale & retail | 2025 |
| Red FOX Audit & Accountancy Limited | Extraterritorial | 2023 |
| Red FOX Networks Limited | Extraterritorial | 2023 |
| Red Moto Ltd | Manufacturing | 2017 |
| Red Room Bars Limited | Hospitality | 2025 |
| Red Squirrel Taverns Limited | Hospitality | 2026 |
| Redas Ltd | Construction | 2023 |
| Redco 66 Ltd | Professional & scientific | 2021 |
| Redeemed Christian Church of GOD Harvest Centre Stafford Limited | Other services | 2025 |
| Redefining Real Estate Limited | Construction | 2021 |
| Redler Properties Limited | Real estate | 2020 |
| Redmondhewitt Ltd | Manufacturing | 2020 |
| Reedowen Construction Management Ltd | Professional & scientific | 2016 |
| Reel Breaks Ltd | Hospitality | 2025 |
| Reep & MAX Development UK Limited | Manufacturing | 2022 |
| Reespect PR Ltd | Administrative & support | 2004 |
| Reeves Testing Ltd | Information & communication | 2019 |
| Refined Network Technology Co., Ltd. | Information & communication | 2025 |
| Reflections (2020) Limited | Other services | 2020 |
| Regal Care Services Limited | Health & social care | 2019 |
| Regenerate World Co., Ltd | Wholesale & retail | 2023 |
| Regenerative Health Clinic Ltd | Health & social care | 2022 |
| Regenerative Health Ltd | Health & social care | 2018 |