| ME Technologies Ltd | Professional & scientific | 2014 |
| Meadowbank Engineering Limited | Professional & scientific | 2026 |
| Mean Peach Ltd | Information & communication | 2000 |
| Mears Transport Ltd | Wholesale & retail | 2018 |
| Meat Freaks Ltd | Hospitality | 2025 |
| MEB Labs Ltd | Information & communication | 2025 |
| MEC COM Limited | Manufacturing | 2000 |
| Medfriend Co., Ltd | Wholesale & retail | 2010 |
| Media Car Promotions Limited | Professional & scientific | 2022 |
| Media Message (Midlands) Limited | Professional & scientific | 2008 |
| Medianet Systems Limited | Information & communication | 2011 |
| Medrano Technology Ltd | Wholesale & retail | 2025 |
| Medsafe Limited | Manufacturing | 2024 |
| Medusa Direct Communications Ltd | Arts & recreation | 2025 |
| Medwin ETH Trading Co., Ltd | Wholesale & retail | 2024 |
| MEE Refurb Limited | Construction | 2002 |
| Meeizzicog Ltd | Wholesale & retail | 2025 |
| Mega Metals Ltd | Water & waste | 2019 |
| Mele Outdoor Furniture Co., Ltd | Extraterritorial | 2015 |
| Meli Property Solutions Limited | Construction | 2013 |
| Melior Esse Limited | Professional & scientific | 2022 |
| Mellifluous International Trade Co., Ltd | Wholesale & retail | 2025 |
| Mellish Park Management Company Limited | Administrative & support | 2006 |
| Mellons Holdings Limited | Professional & scientific | 2020 |
| Mend Your Motor Limited | Wholesale & retail | 2013 |
| Meniq Elegance Limited | Manufacturing | 2026 |
| Meravix Ltd | Wholesale & retail | 2025 |
| Mercian Facilities Limited | Professional & scientific | 2025 |
| Mercian Grounds Management Limited | Administrative & support | 2025 |
| Mercian Groundworks Limited | Administrative & support | 2025 |
| Mere Lane Farm Ltd | Wholesale & retail | 2025 |
| Meridian Consult Ltd | Professional & scientific | 2003 |
| Meritflow Trading Limited | Wholesale & retail | 2025 |
| Merlio Commerce Ltd | Wholesale & retail | 2025 |
| Meroy Funk Ltd | Wholesale & retail | 2025 |
| Merryn Properties Limited | Real estate | 2016 |
| Mescell Petroleum Company Ltd | Mining & quarrying | 2022 |
| Mesh Wiring Systems Ltd | Professional & scientific | 2020 |
| Meta Graphite Ltd | Hospitality | 2021 |
| Meta Jewellery Ltd | Wholesale & retail | 2019 |
| Meta-Noia Group Ltd | Wholesale & retail | 2024 |
| Metal Beds Holdings Limited | Wholesale & retail | 2017 |
| Metal Beds Limited | Wholesale & retail | 2004 |
| Metal Import and Export Co., Ltd | Wholesale & retail | 2021 |
| Metaland UK Ltd | Wholesale & retail | 2018 |
| Metaverse Capital Holdings Ltd | Financial services | 2021 |
| Metro Express Stores Ltd | Wholesale & retail | 2019 |
| Metrocad (UK) Ltd | Professional & scientific | 2011 |
| Mexsol Limited | Information & communication | 2004 |
| MFS Energy Limited | Construction | 2026 |
| MGK Trade Limited | Wholesale & retail | 2023 |
| MI AMI Property Ltd | Real estate | 2017 |
| Michael Brough Electric Limited | Construction | 2010 |
| Michelle Gomes Interiors Limited | Professional & scientific | 2017 |
| Michville Ltd | Information & communication | 2010 |
| Micklewood Liveries Limited | Other services | 2019 |
| Micro Passion Ltd | Information & communication | 2012 |
| MID - Staffordshire Medical Education Centre | Education | 1994 |
| MID Staffs Transport Ltd | Transport & logistics | 2015 |
| Middle Coppice Management Limited | Real estate | 2014 |
| Middle Well Industrial Co., Ltd | Extraterritorial | 2023 |
| Midland Aluminium Ltd | Construction | 2017 |
| Midland Collaborative Pictures Ltd | Information & communication | 2023 |
| Midland Control System Integrators Ltd | Manufacturing | 2015 |
| Midland Home Surveys Limited | Professional & scientific | 2025 |
| Midland Machine Tools Ltd | Wholesale & retail | 2015 |
| Midland Master Sweeps & Home Fires Ltd | Administrative & support | 2026 |
| Midland Property Company (Walsall) Limited | | 1959 |
| Midland School Services Limited | Administrative & support | 2017 |
| Midland Service Contractor Limited | Manufacturing | 2026 |
| Midland Tax Solutions Limited | Extraterritorial | 2012 |
| Midland Testing Ltd | Information & communication | 2016 |
| Midland Travel Trade Club Ltd | Administrative & support | 2012 |
| Midland Utility Services Limited | Construction | 2014 |
| Midlands Aesthetics Training Academy Limited | Extraterritorial | 2022 |
| Midlands Building Maintenance Ltd | Construction | 2024 |
| Midlands Community Services Ltd | Health & social care | 2005 |
| Midlands Driver Supply Limited | Transport & logistics | 2016 |
| Midlands Finance Limited | Financial services | 2004 |
| Midlands Floor Screeding Limited | Construction | 2012 |
| Midlands Liquid Screeding Limited | Construction | 2021 |
| Midlands Magazines Limited | Manufacturing | 2018 |
| Midlands Portable Buildings Limited | Construction | 2005 |
| Midlands Psychology C.I.C | Health & social care | 2008 |
| Midlands Radio Holdings Limited | Information & communication | 2025 |
| Midlands Recycle Limited | Water & waste | 2025 |
| Midlands Van Centre Ltd | Wholesale & retail | 2023 |
| Midway Boats Limited | Manufacturing | 1997 |
| Midway Property Group Ltd | Real estate | 2025 |
| Mifa Trading Co., Ltd | Manufacturing | 2022 |
| Mihai Virgil Ltd | Transport & logistics | 2022 |
| Mike Emmons Ltd | Administrative & support | 2022 |
| Mikzon Trading Co., Ltd | Wholesale & retail | 2023 |
| Mileburne Charollais Ltd | Agriculture & fishing | 2013 |
| Milestone Minibuses Limited | Transport & logistics | 2025 |
| Milford Group Ltd | Hospitality | 2020 |
| Militree ARB Ltd | Administrative & support | 2024 |
| Mill Bank Surgery GPF Limited | Professional & scientific | 2013 |
| Mill Farm Recycling Limited | Water & waste | 2024 |
| Mill Meece Barns Management Limited | Households | 2019 |